Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT05294029Recruiting
Study of movement and aging in adults with neuromotor disability
This study looks at how neuro-related movement problems change as people age. It may help improve care plans for adults with neuromotor disabilities by learning what happens over time.
GarchesAges 18 years+ - NCT05663008Recruiting
Testing nerve-to-muscle signal changes to diagnose movement diseases
This study measures how nerves communicate with muscles, using recordings and gels. It aims to spot early, personalized signs of conditions like ALS and related diseases, and to improve diagnosis.
Dublin, LeinsterAges 18 years+ - NCT05685706Recruiting
Study of spine alignment after hip or knee replacement
This study looks at how the alignment of your spine relates to your walking and posture after hip or knee replacement surgery for wear-and-tear arthritis. It may help doctors better understand how to monitor recovery and long-term function.
Taichung, North DistrictAges Any age - NCT04858347Recruiting
Study of a specific knee implant and recovery outcomes
This trial looks at how well a particular knee replacement (a GEMINI SL fixed-bearing prosthesis) works and how people function after surgery. It may help doctors learn what to expect for recovery and long-term results with this implant.
Cali, Valle del Cauca DepartmentAges 18–80 - NCT05683314Recruiting
Surgery comparison for unstable pelvic and hip socket fractures
This study looks at how to best surgically fix unstable pelvic and acetabular (hip socket) fractures, comparing different operative approaches. You might benefit if your goal is stable healing with a less invasive internal fixation method, but the study requires specific fracture types and long follow-up time.
Taichung, North DistrictAges Any age - NCT05701592Recruiting
Testing two-bundle surgery for a torn knee ligament
This trial studies outcomes after a specific type of knee surgery for a torn ligament in the back of the knee. It may help people with a confirmed ligament tear who have pain and instability, by improving how well the knee works after reconstruction.
Bełchatów, Łódź VoivodeshipAges 18 years+ - NCT05044767Recruiting
Hip replacement study using specific implant brands
This study checks how safe and how well specific hip replacement implants work after hip replacement surgery. You might be eligible if your surgeon plans to use an ATF Implants and/or Lapé Médical prosthesis and you don’t have certain health issues that can make surgery riskier.
BordeauxAges Any age - NCT04607538Recruiting
Study of knee joint shape and patella dislocations in Faroese teens
This study looks at how knee joint shape differences may relate to repeated kneecap (patella) instability or near-dislocation, and what that means long-term. It specifically includes teens from the Faroe Islands and asks about symptoms and knee function over time.
HvidovreAges 15–20 - NCT02653079Recruiting
Blood testing and low-dose radiation for painful joint conditions
This study collects blood samples and treats certain painful joint/soft-tissue problems with low-dose local radiation therapy. It aims to understand disease features and how patients may respond to this treatment.
Erlangen, BavariaAges 18 years+ - NCT05734651Recruiting
Study of PROMIS stem in hip replacement patients
This study looks at people who had a hip replacement (total hip arthroplasty) using the PROMIS stem. The goal is to evaluate how this specific hip part performs in real-world use.
Sankt Johann in Tirol, TyrolAges 18 years+ - NCT05713149Recruiting
Treating pressure sores with surgery and anti-bacterial medicines
This study looks at whether combining a surgical skin flap with anti-bacterial treatment can improve pressure sores that are complicated by bone infection (osteomyelitis). It targets adults who have nerve/movement problems that put them at high risk for these sores.
GarchesAges 18 years+ - NCT05574582Recruiting
Keyhole versus open surgery for an unhealed scaphoid bone
This study compares two surgical approaches—keyhole surgery versus open surgery—for scaphoid fractures that are not healing on their own. It aims to see which approach better helps the scaphoid heal after a delay or complete non-healing.
HellerupAges 18–68 - NCT04462458Recruiting
Study tracking outcomes after ACL reconstruction surgery
This is a study that follows adults who had an ACL tear treated with ACL reconstruction. It helps understand how the surgical device/material performs in real-world care.
InnsbruckAges 18 years+ - NCT04236492Recruiting
Fresh cartilage graft study for large knee joint damage
This trial studies how well a fresh cartilage and bone graft works to repair large, full-thickness defects in the knee. It also looks at imaging results (pictures of the knee) to see how the repair is healing over time.
Barcelona, CataloniaAges 15–50 - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT05781763Recruiting
High-intensity exercise for spondyloarthritis pain and stiffness
This study tests whether a structured, high-intensity exercise program can improve symptoms in people with axial spondyloarthritis. It compares the exercise approach against another group to see if it helps function and well-being.
Halmstad, Halland CountyAges 18–67 - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT00390104Recruiting
Study uses blood and skin samples to learn muscular disease causes
This study looks at samples from people with muscular dystrophy and from close relatives, to better understand neuromuscular diseases. You may be asked to provide a skin biopsy for research to help with genetic and molecular analysis.
Boston, MassachusettsAges 1 week–100 years - NCT03608280Recruiting
3D-printed implant vs own bone for rebuilding eye socket
This study compares two ways to rebuild part of the eye socket bone: a 3D-printed implant versus using the patient’s own bone. It may help show which approach works better to restore eye position and symptoms like double vision after an injury or surgery.
Pierre-BéniteAges 18–90 - NCT05868434Recruiting
Surgery for unstable kneecap after dislocation
This trial looks at a surgical repair to stop a kneecap (patella) that keeps slipping out of place after a lateral dislocation. It’s intended for people whose symptoms did not improve with non-surgical treatments.
Bełchatów, Łódź VoivodeshipAges 18 years+ - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT05231343Recruiting
Dual small-plate vs single plate for broken collarbones
This trial compares two surgical plate methods to fix a broken collarbone in the middle part (midshaft). The goal is to see which method works better for healing and function after an acute, fully displaced fracture.
Toronto, OntarioAges 18–65 - NCT05882591Recruiting
Treating a specific inner-knee cartilage and meniscus problem
This trial looks at a treatment for a specific knee alignment and tissue problem inside the inner (medial) part of your knee. It may help people whose deep-squat knee pain is caused by rubbing (“impingement”) between the femur and the back part of the medial meniscus.
Bełchatów, Łódź VoivodeshipAges 18–70 - NCT05883995Recruiting
Phage therapy clinic program in Lyon
This trial is an organized clinic to help patients request bacteriophage (phage) therapy. It mainly checks that you were referred to the Lyon hospital for a phage therapy request and that you agree to be part of the program.
LyonAges Any age
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.