Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07564921Enrolling by invitation
Nutrition and Muscle Strength in Multiple Sclerosis With Swallowing Difficulty
This study looks at how nutritional status and muscle function relate to each other in people with multiple sclerosis who have difficulty swallowing. Understanding this connection may help doctors better support patients with MS who struggle with eating and drinking.
Gaziantep, şehitkamilAges 18–65 - NCT07563387Enrolling by invitation
Ear Stimulation to Help Speech Recovery After Stroke or Brain Injury
This study tests whether a gentle electrical stimulation applied to a nerve in the ear can help improve speech and language abilities in people who have had trouble speaking since a stroke or traumatic brain injury. The goal is to see if this non-invasive treatment can help rewire the brain to recover language skills.
Jacksonville, FloridaAges 18–80 - NCT07563101Enrolling by invitation
Understanding Visual Hallucinations in Low Vision Patients
This study investigates Charles Bonnet Syndrome, which causes people with significant vision loss to see things that aren't there (visual hallucinations). Researchers want to better understand why this happens and how it affects patients' quality of life.
RomaAges 40–70 - NCT07560306RecruitingPhase 3
New Heart Scan to Detect Blood Clots in Amyloid Heart Disease
This study tests a new type of imaging scan ([64Cu]FBP8 PET) to detect blood clots that may form in the heart's left atrial appendage (a small pouch in the heart) in patients with amyloid cardiomyopathy (a disease where abnormal protein builds up in heart muscle) who also have irregular heartbeat. The scan may help doctors catch clots earlier and prevent strokes.
Boston, MassachusettsAges 18 years+ - NCT06635291Recruiting
Better Diagnosis for Children with Brain Injury
This study tests new ways to evaluate children with severe brain injuries who are in a vegetative or minimally conscious state. The goal is to improve diagnosis and care for children with serious disorders of consciousness after a brain injury.
Bosisio Parini, LeccoAges 2 months–25 years - NCT06528964Recruiting
Skin protein study for Alzheimer's, Parkinson's, and related disorders
This study looks at the skin of people with memory or movement disorders (like Alzheimer's, Parkinson's, ALS) to find proteins that may help diagnose these conditions. If you have one of these diseases or are a healthy older adult, you may be able to join by giving a small skin sample.
San Luis Potosí CityAges 45 years+ - NCT06643312Recruiting
Treadmill training with spinal stimulation for standing after spinal cord injury
This trial tests whether combining treadmill training with spinal cord stimulation (TPAD) can help people with severe spinal cord injuries regain the ability to stand. It aims to improve standing function and may lead to better recovery.
West Orange, New JerseyAges 18 years+ - NCT06736249Recruiting
Testing a new treatment for muscle loss in sarcopenia
This trial tests a new approach to treat sarcopenia (age-related muscle loss) by targeting a protein called HIF-1α. It compares older adults with sarcopenia to younger adults without it, all of whom are having hip or knee surgery.
Milan, EuropeAges 65–90 - NCT06736951Recruiting
Changing the hospital room to prevent confusion in older adults
This study tests whether changing the hospital room environment can help prevent confusion (delirium) in older adults who are not in intensive care. If you are 70 or older and admitted to a regular hospital unit, you may be able to take part.
Baytown, TexasAges 70 years+ - NCT06734598RecruitingPhase 4
Botox for Jaw Tightness After Head and Neck Radiation
This study tests whether Botox injections into the jaw muscles can help head and neck cancer survivors who have trouble opening their mouths (trismus) after radiation therapy. If you have tight or painful jaw muscles and limited mouth opening, this treatment may offer relief.
TaipeiAges 18 years+ - NCT06730438Recruiting
Sound wave brain treatment for early dementia
This study tests whether a treatment called Transcranial Pulse Stimulation (using targeted sound waves) can help people with early-stage dementia. It aims to find a new way to improve brain function without surgery or drugs.
L’Aquila, ItalyAges 18 years+ - NCT05315167RecruitingPhase 1/Phase 2
Study drug PRJ1-3024 for advanced solid tumors
This trial tests how safe PRJ1-3024 is and how the body handles it, and it also looks for early signs that it can shrink advanced solid tumors. It may help people whose cancer can’t be treated with standard options.
Zhengzhou, HenanAges 18 years+ - NCT05560724Recruiting
Brain stimulation after stroke to track recovery signals
This study looks at whether brain stimulation and brain scans can help measure recovery after an ischemic stroke. It may help researchers understand who benefits from non-invasive brain stimulation by using brain “signal” markers.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06167239Recruiting
Breathing muscle training for Guillain-Barre patients on ventilators
This trial compares two methods to help people with Guillain-Barre syndrome who are having trouble breathing on their own after being on a ventilator. It tests if adjusting the ventilator's sensitivity or doing specific breathing muscle exercises can improve blood oxygen levels and help them wean off the machine.
CairoAges 20–55 - NCT06727006Recruiting
Rescue stenting and clot-dissolving medicine for severe stroke
This trial tests whether using a stent plus a clot-dissolving drug can improve outcomes for people with a large-vessel stroke who are having a procedure to remove the clot. It is designed for patients who can receive treatment within 24 hours of their first symptoms.
Bergamo, ItalyAges 18 years+ - NCT06737549RecruitingPhase 4
Electroacupuncture and NGF for swallowing problems after stroke
This study tests whether a specific type of electroacupuncture (a gentle needle therapy with mild electrical pulses) plus a nerve growth factor injection can help people who have trouble swallowing after a recent stroke. The goal is to see if this combination improves swallowing function better than standard care.
Hangzhou, ZhejiangAges 18–80 - NCT06730074Recruiting
Robotic exercise for Parkinson's motor and thinking skills
This study tests a new robotic system that combines movement and mental exercises for people with Parkinson's. It may help improve both your physical and thinking skills.
Ofakim, SouthAges 50–75 - NCT06737250RecruitingPhase 2
Testing a new drug combo for relapsed brain lymphoma
This trial tests a combination of three drugs (poseltinib, rituximab, and lenalidomide) for people with primary central nervous system lymphoma that has come back or not responded to earlier treatment. The goal is to see if this new mix can help control the disease.
BusanAges 19–80 - NCT05415501Recruiting
Sentence practice training for people with post-stroke aphasia
This study tests a training program designed to help people with aphasia—trouble making sentences—after a stroke. It may help improve sentence use and communication by practicing targeted sentence production skills.
West Lafayette, IndianaAges 21–85 - NCT05000528Recruiting
Program teaching for long-term insomnia patients
This trial tests whether a structured patient education program helps people with chronic insomnia sleep better and feel better. You would likely learn sleep-focused strategies and receive support aimed at improving sleep habits.
NîmesAges 18 years+ - NCT07559097RecruitingPhase 1/Phase 2
Methotrexate-loaded vesicles injected into spine fluid for lung cancer spread to brain membranes
This study tests a new way to deliver a cancer drug directly into the fluid around your brain and spinal cord to treat lung cancer that has spread to the membranes covering the brain. It may help patients whose cancer hasn't responded to standard treatments.
Zhengzhou, HenanAges 18 years+ - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07558642Recruiting
Nerve Block to Reduce Confusion in Older ICU Patients
This study tests whether a nerve-blocking injection (stellate ganglion block) can reduce confusion and help restore normal sleep-wake cycles in older adults staying in the intensive care unit. Researchers hope this treatment may help patients recover faster and feel more alert.
Antalya, MuratpaşaAges 65–99 - NCT07553338RecruitingPhase 2
Leronlimab Safety and Brain Inflammation in Alzheimer's
This study tests whether a drug called leronlimab is safe and can reduce inflammation in the brains of people with mild-to-moderate Alzheimer's disease or memory problems. Researchers will use special brain scans to see if the drug affects inflammation.
New York, New YorkAges 50 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.