Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03396562Recruiting
Study of early development in babies with extra sex chromosomes
This study follows infants and young children with conditions caused by having an extra sex chromosome (like XXY, XYY, or XXX) to learn how health and development unfold over time. It may help families and doctors understand what to expect and what support could be helpful.
Aurora, ColoradoAges 1 month–1.1 years - NCT03399929Recruiting
Tracking long-term recovery after brain injury or stroke
This study looks at how people do over the long term after a stroke or a traumatic brain injury (brain injury from an accident). It may help researchers understand recovery and improve future support and care.
Encino, CaliforniaAges 18 years+ - NCT03399175Recruiting
Early immune-suppressing treatment for VKH eye disease
This trial studies giving immune-suppressing treatment early in Vogt-Koyanagi-Harada (VKH) disease to see if it improves outcomes. It may help people reduce ongoing eye inflammation if they qualify and can be followed for a longer time.
São Paulo, São PauloAges 10–70 - NCT03400371Recruiting
Study of brain signals in juvenile myoclonic epilepsy
This study looks at EEG brain recordings in people with juvenile myoclonic epilepsy, especially those whose seizures started between ages 10 and 25. It may help researchers better understand how this epilepsy works and improve future care.
New York, New YorkAges 10–40 - NCT03404336Recruiting
Well-being therapy for chronic migraine in outpatients
This study tests whether a “well-being therapy” program can reduce symptoms of chronic migraine compared with a control therapy. You may qualify if you have long-lasting chronic migraine and can follow the study schedule.
Florence, FlorenceAges 18–65 - NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT03401762Recruiting
Wearable device training for stroke arm coordination
This trial tests a wearable device and training task to help improve how stroke-affected arm muscles work together. It may help reduce unwanted “extra muscle effort” and improve control in people with recent or long-term stroke.
Chicago, IllinoisAges 21 years+ - NCT03402854Recruiting
Brain stimulation plus arm therapy for children with one-sided CP
This study tests whether a non-painful brain stimulation treatment plus bimanual (two-hand) arm therapy can improve arm and hand use in children with congenital hemiplegic cerebral palsy. It may help children strengthen and control the affected hand and improve daily movement.
White Plains, New YorkAges 6–18 - NCT03409133Recruiting
Neural feedback training for people with leg amputations
This study tests whether a nerve-based “feedback” system can help people with below-knee or above-knee amputations during standing and walking. It focuses on whether the training and device setup are safe and workable for participants over the study period.
Cleveland, OhioAges 18 years+ - NCT03409003Recruiting
Carbaglu monitoring study for suspected NAGS deficiency
This study follows people who have (or might have) NAGS deficiency and who are taking Carbaglu to treat it. The goal is to better track safety and health outcomes over time.
Washington D.C., District of ColumbiaAges Any age - NCT03416114Recruiting
Registry for people with rare primary headache types
This trial is a registry that collects information about rare types of primary headaches in specialized Italian headache clinics. It may help researchers better understand these conditions and improve future care.
FlorenceAges Any age - NCT03418441Recruiting
Study infections of the brain and spinal fluid in Denmark
This trial focuses on people in Denmark who may have an infection in the brain or the fluid around the brain and spinal cord. Researchers aim to collect and compare diagnostic results for different infection types (viral meningitis, bacterial meningitis, encephalitis, and others) to help confirm the cause and guide care.
AalborgAges 18 years+ - NCT03418961RecruitingPhase 3
Study of heart-risk management for metastatic HER2 breast cancer
This trial follows people with metastatic HER2-positive breast cancer who are at higher risk for heart damage while on HER2-targeted therapy. Some participants are randomly assigned to different monitoring/heart-protection approaches to see what best helps keep the heart safe.
Anchorage, AlaskaAges 18 years+ - NCT03428009Recruiting
Study links dystonia symptoms to genetic and brain differences
This study looks at how different types of dystonia (movement disorders) relate to genetics and brain findings from scans. You might help researchers understand why symptoms look different from person to person and what patterns may matter.
Dallas, TexasAges 11 years+ - NCT03434548Recruiting
Imaging study for early and late Huntington’s disease changes
This study uses repeat brain scans (including PET and MRI) to track changes in the brain caused by Huntington’s disease over time. It may help researchers understand disease progress and test how well the scans reflect early vs later disease.
London, EnglandAges 21–75 - NCT03446326Recruiting
Check how your pacemaker changes heart pumping
This study measures how well the heart pumps at different heart rates in people with pacemakers or defibrillators. It may help doctors understand how pacing settings affect heart function.
Calgary, AlbertaAges 18–70 - NCT03449238RecruitingPhase 1/Phase 2
Pembrolizumab with focused brain radiation for breast cancer brain spread
This trial studies whether pembrolizumab (an immune therapy medicine) plus stereotactic radiosurgery (focused radiation) can better control brain metastases from breast cancer. It may help shrink or slow growth of multiple brain spots with minimal treatment to surrounding tissue.
New York, New YorkAges 19–90 - NCT03445949RecruitingPhase 4
Best blood-thinner plan after a left heart device procedure
This trial compares which two medicines work best after a device closes off a part of the heart called the left atrial appendage. It may help reduce stroke risk while balancing bleeding risk after your procedure.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT03452774Recruiting
AI matches your cancer tests to possible treatment trials
This trial uses an AI system to help match people with certain cancer types and specific tumor test results (like gene or protein markers) to relevant clinical trials. It may help you and your doctor find studies that fit your cancer biology faster.
Birmingham, AlabamaAges Any age - NCT03452202Recruiting
Brain stimulation to improve speech after stroke
This trial studies whether gentle brain stimulation (tDCS) can improve speech after a stroke. It focuses on people with stroke-related apraxia of speech while carefully checking hearing, brain function, and safety with devices or metal.
New York, New YorkAges 18–99 - NCT03457493RecruitingPhase 1/Phase 2
TSPO brain scan study in Parkinson’s disease
This trial looks at brain inflammation in people with Parkinson’s using a special PET scan. The goal is to understand how brain immune activity may relate to Parkinson’s, and how the scan results change over time.
Birmingham, AlabamaAges 30 years+ - NCT03455478Recruiting
Study of adult vision health in Shanghai residents
This study looks at the eye health of adults who live in Shanghai. It may help researchers understand vision problems in the local population and improve future eye care.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT03457831Recruiting
Check a treatment approach for prolonged seizure emergencies
This trial is for adults in the intensive care unit who are having seizures that last at least 5 minutes or keep coming back without fully recovering. It tests a study approach for managing a dangerous seizure emergency and may help doctors improve care for critically ill patients.
AngoulêmeAges 18 years+ - NCT03470467Recruiting
ICU study of a reversible brain swelling condition
This trial looks at Posterior Reversible Encephalopathy Syndrome (PRES) in adults in the ICU. It may help doctors better understand and manage a condition that can cause seizures, confusion, headaches, and vision problems, and that typically shows specific changes on brain scans.
Le ChesnayAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.