Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT05715411Recruiting
Light therapy for long sleep-onset insomnia
This trial studies whether timed light exposure can help people who have trouble falling asleep. It aims to improve insomnia symptoms by testing a light-based approach while carefully measuring sleep patterns.
StrasbourgAges 30–60 - NCT06976216RecruitingPhase 3
Study of KarXT plus KarX-EC for Alzheimer's cognitive symptoms
This trial tests a new combination treatment (KarXT plus KarX-EC) to see if it can help with thinking and memory problems caused by Alzheimer's disease. It is for people with mild to moderate Alzheimer's who have a caregiver available.
Long Beach, CaliforniaAges 60–85 - NCT03898804Recruiting
ReHAB brain-computer training for people with arm paralysis
This trial tests whether the ReHAB system can be safely used to help people with “tetraplegia” (arm and hand weakness from spinal cord injury or stroke) control tasks using brain signals. Because it’s an early feasibility study, the main goal is to see if the approach works well enough and is practical to do long-term.
Cleveland, OhioAges 22–65 - NCT07663292Recruiting
Exercise program to improve walking after stroke
This study tests whether a 12-week exercise program can help people who have had a stroke walk better. It focuses on those with a slower walking speed and uses brain scans to see if exercise can trigger positive changes in the brain.
Atlanta, GeorgiaAges 18–80 - NCT07649681Recruiting
AI nutrition help for taste changes from cancer treatment
This study tests whether an AI-powered nutrition program can help people with taste changes caused by cancer therapy. You'll get personalized recipe suggestions and nutrition advice through an online portal to help you eat better during treatment.
Augsburg, BavariaAges 18 years+ - NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+ - NCT06409143Recruiting
Brain stimulation for better arm recovery after stroke
This study tests a gentle form of brain stimulation to help improve arm and hand movement after a stroke. It looks at whether this approach can aid recovery in both recent and long-standing stroke survivors.
HsinchuAges 18 years+ - NCT04292574Recruiting
UK Spinal Muscular Atrophy patient registry
This trial is a registry that collects health information from people with spinal muscular atrophy (SMA). It helps researchers understand the condition better and may support future studies and treatments.
Newcastle upon TyneAges Any age - NCT05789173RecruitingEarly Phase 1
Testing how genetics affect drug levels with methadone
This early study tests how a person’s genetic makeup may change how fast certain medicines move through the body. It compares drug levels when combined with methadone and tizanidine, aiming to understand safer dosing and effects.
Indianapolis, IndianaAges 18–65 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Birmingham, AlabamaAges 18 years+ - NCT06788262Recruiting
Brain health study for female pro soccer players
This study looks at how heading the ball and minor head impacts might affect the brain and thinking skills in female professional soccer players, compared to tennis players. It aims to help understand any long-term effects of playing soccer.
StrasbourgAges 32–65 - NCT04150198Recruiting
PET-MR brain scan study of resilience in Alzheimer’s
This study uses a combined PET and MRI brain scan to understand why some people with Alzheimer’s (and related “focal” types) may cope better than expected. It may help researchers find brain patterns linked to resilience and to different Alzheimer’s subtypes.
OrsayAges 40–80 - NCT05844982RecruitingPhase 3
Eye injections or steroid implant to prevent vision loss
This trial studies ways to prevent worsening vision caused by radiation damage to the retina after plaque brachytherapy for uveal melanoma. You may be randomly assigned to a medication injection, a steroid implant, or observation to see which approach best protects vision.
Palo Alto, CaliforniaAges 18 years+ - NCT07771829Recruiting
Nerve blocks for pain after hip replacement
This trial compares two types of nerve blocks to see which better controls pain after hip replacement surgery and may reduce the need for pain medications. It helps determine the most effective pain management approach for recovery.
Wuhan, HubeiAges 18–70 - NCT07221292RecruitingPhase 3
Study of N-acetyl-L-leucine for CACNA1A disorders
This trial tests a potential treatment for people with CACNA1A disorders, which can cause movement problems, migraine, or seizures. The medication may help improve balance and coordination.
Baltimore, MarylandAges 4 years+ - NCT07067736Recruiting
Cefazolin Dose Before Shunt Surgery: Checking Brain Fluid Levels
This study measures how well the antibiotic cefazolin reaches the fluid around your brain and spine when given right before shunt surgery. It may help doctors choose the best dose to prevent infections.
StrasbourgAges 18 years+ - NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Dothan, AlabamaAges 18 years+ - NCT07741071RecruitingPhase 2
Vitamin B3 supplement for early Alzheimer's disease
This study tests whether a daily supplement (nicotinamide riboside, a form of vitamin B3) can slow the progression of early Alzheimer's disease over two years. It is a randomized, double-blind trial, meaning half the participants will get the supplement and half will get a placebo (a pill with no active ingredient), and neither you nor the doctors will know which you are getting.
BergenAges 50–85 - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT04545502Recruiting
Study of aortic grafts and heart patches after aortic surgery
This study looks at how well certain aortic grafts and cardiovascular patches work after surgery. It may help by improving care for people who need these devices, and by collecting safety and outcome information over time.
Aurora, ColoradoAges 18 years+ - NCT07260864Recruiting
rTMS for fibromyalgia pain
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce pain in people with fibromyalgia. If you join, you'll receive rTMS sessions and we'll monitor your brain activity to see how it affects your pain.
Rochester, New YorkAges 18–65 - NCT05976685Recruiting
Close the left atrial appendage after stroke despite blood thinners
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
BrugesAges 18 years+ - NCT06881407Recruiting
Robot and VR games to improve arm use in kids with cerebral palsy
This study tests if playing virtual reality games with a humanoid robot can help children with cerebral palsy improve arm function. Your child would play fun games while using their arm, which may strengthen movement and coordination.
Atlanta, GeorgiaAges 5–21 - NCT07769814Recruiting
Better CT imaging for brain stent checkups
This study looks at whether a new type of CT scanner can take clearer pictures of stents in the brain. The goal is to help doctors see if the stent is working well after it's been placed.
Beijing, Beijing MunicipalityAges 5–90
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.