Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05808478Recruiting
Eye-tracking tool for kids who cannot speak well
This trial tests an eye-tracking technology that lets children communicate by using where they look on a screen. It may help children with severe communication needs do tasks and use simple functions without needing speech or hand control.
MessinaAges 3–17 - NCT05322824Recruiting
Study for adults with narrowed brain or neck arteries
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05129748RecruitingPhase 2
Prevent hearing damage during cisplatin chemotherapy
This Phase 2 trial tests whether sodium thiosulfate and mannitol can reduce hearing damage (ototoxicity) in adults receiving cisplatin chemotherapy. It may help protect hearing while you get cancer treatment.
Toronto, OntarioAges 18 years+ - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT04844060Recruiting
Study collecting spinal fluid from patients needing a lumbar puncture
This study collects cerebrospinal fluid (the fluid around the brain and spinal cord) during a lumbar puncture. It aims to improve how doctors use this information for accurate diagnosis in patients who need the procedure.
StrasbourgAges Any age - NCT00390104Recruiting
Study uses blood and skin samples to learn muscular disease causes
This study looks at samples from people with muscular dystrophy and from close relatives, to better understand neuromuscular diseases. You may be asked to provide a skin biopsy for research to help with genetic and molecular analysis.
Boston, MassachusettsAges 1 week–100 years - NCT04805255Recruiting
Study brain-targeted radiation for limited brain metastases
This study looks at people with a small number of brain metastases who are treated with a focused, staged form of radiation after surgery or to treat the cancer. It may help doctors better understand how well this approach works and who benefits most.
TaoyuanAges 18–84 - NCT05839418Recruiting
Registry study for people with status epilepticus
This study records information about people who are in the hospital with status epilepticus (prolonged seizure activity) to better understand care for refractory cases. If you qualify, your team may collect your clinical details during your hospital stay rather than giving a new treatment as part of the study.
LinzAges 18 years+ - NCT05630586RecruitingPhase 2
Semaglutide shot for early stroke recovery
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
AarhusAges 18 years+ - NCT05835674Recruiting
Early brain screening and therapy planning for babies at CP risk
This trial aims to find and support babies who are at risk of cerebral palsy (CP) as early as possible. It checks specific early signs and brain or health risk factors, then helps determine whether early intervention might improve outcomes.
AalborgAges 3 months–1 year - NCT05834855RecruitingPhase 3
Rituximab versus ocrelizumab for relapsing multiple sclerosis
This Phase 3 trial compares two similar immune therapies—rituximab and ocrelizumab—to see if rituximab works about as well for relapsing multiple sclerosis. It may help you and researchers understand which option is equally effective and safe for preventing relapses and disease activity.
AmsterdamAges 18 years+ - NCT02504788Recruiting
Protect the brain’s memory area during whole-brain radiation
This study tests whether avoiding the hippocampus (a part of the brain important for memory) during whole-brain radiotherapy can slow down thinking and memory decline. It may help some people preserve neurocognitive function while still treating brain metastases.
TaoyuanAges 18–84 - NCT02448992RecruitingPhase 2/Phase 3
Brain radiation that avoids the memory area in lung cancer
This trial studies a “prophylactic” (preventive) type of brain radiation for people with lung cancer that has spread to nearby lymph nodes but not to the brain. It aims to lower the chance of brain metastases while protecting the hippocampus, an area linked to memory.
TaoyuanAges 18–80 - NCT04006561Recruiting
Brain lymphoma study using targeted whole-brain radiation
This trial studies how newly diagnosed primary central nervous system (brain) non-Hodgkin lymphoma responds to a specific type of radiation to the whole brain, and it also looks at changes in thinking, mood, and behavior. It may help doctors understand how this treatment affects day-to-day brain function.
TaoyuanAges 18–80 - NCT05727111Recruiting
Home therapy program for people with long-term stroke
This trial tests a structured therapy program done at home to help with movement after chronic stroke. It may help if you have lasting arm/hand problems and can follow simple instructions with a caregiver’s daily support.
BrusselsAges 18–100 - NCT05853796Recruiting
Studying stroke warning signs in young adults
This observational study follows people ages 18–50 who had a first TIA (“mini-stroke”) or an acute ischemic stroke to better understand what happens after the event. It may help improve future care by tracking symptoms, imaging findings, and recovery over time.
Nijmegen, GelderlandAges 18–50 - NCT02686229Recruiting
Registry study for adults with suspected low-grade brain tumor
This study records health details about adults who may have a low-grade glioma (a slower-growing brain tumor) based on scan results. Researchers use these data to better understand disease patterns and outcomes, and help connect individual patients to future research.
UlmAges 18 years+ - NCT05561088Recruiting
Head acupuncture after stroke clot removal
This trial studies whether doing head acupuncture after a procedure to remove a stroke-causing blood clot can improve recovery and safety. You may be considered if you had endovascular clot removal within 24 hours and meet specific brain-scan and stroke-severity measures.
Xi'an, ShaanxiAges 18–100 - NCT03245866Recruiting
Study for bleeding caused by a brain aneurysm rupture
This study is for people admitted with a confirmed brain bleeding caused by a ruptured aneurysm. The goal is to better understand this specific cause of bleeding, which may help improve care for patients with aneurysm-related subarachnoid hemorrhage.
Aarau, Canton of AargauAges Any age - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT04862507Recruiting
Thrombectomy treatment for severe stroke with low ASPECTS
This trial studies an approach for removing a blockage using thrombectomy in people with an acute ischemic stroke that shows a low ASPECTS score. It may help restore blood flow in strokes that have significant early changes on brain imaging.
BerlinAges 18 years+ - NCT05878002Recruiting
Tests thinking, movement, and sleep after clot removal stroke
This study looks at thinking skills, body movement, and sleep patterns in adults after a specific type of stroke treated with a clot-removing procedure. It may help doctors better understand what changes happen after treatment and how to measure them.
RomeAges 18 years+ - NCT02900521Recruiting
Brest stroke and clot registry for local adults
This study is a population registry that records information from people in a specific area of Brest who had certain types of brain blood vessel events. It helps researchers understand how these conditions happen in the real world and may improve future care planning.
BrestAges 15 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.