Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07410039RecruitingPhase 4
Acute treatment for neuromyelitis optica in real-world setting
This study looks at treatments for people with neuromyelitis optica spectrum disorder (NMOSD) who are having a sudden attack affecting their vision or spinal cord. It aims to find out which treatments work best in everyday practice.
BeijingAges 18–65 - NCT07411612Recruiting
Blood markers and confusion after surgery in older adults
This study looks at how inflammation and brain-related substances in the blood after surgery are linked to confusion (delirium) in older adults. It aims to find early warning signs to prevent this common complication.
ViennaAges 65 years+ - NCT06821906RecruitingPhase 2
Stereotactic radiosurgery for essential tremor
This trial tests a precise type of radiation therapy (stereotactic radiosurgery) to treat essential tremor when medications don't work well enough. It aims to reduce shaking without the need for brain surgery.
GliwiceAges 50 years+ - NCT06822920Recruiting
Collagen Patch for Repairing Brain or Spinal Covering
This study is testing a special collagen patch (called Dura Membranes) used by surgeons to repair tears in the outer covering of the brain or spinal cord. If you need this type of repair and don't have a cow collagen allergy, you may be able to join.
Milwaukee, WisconsinAges 18 years+ - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT05198635Recruiting
Cerebral oxygen checks to lower confusion after carotid surgery
This trial looks at whether monitoring oxygen levels in the brain during carotid endarterectomy (a surgery to reduce stroke risk) can help reduce postoperative delirium, a sudden period of confusion after surgery. It may help patients recover more clearly after the operation by identifying risks early and guiding care.
Beijing, Beijing MunicipalityAges Any age - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05632978Recruiting
Study of epilepsy using real-world patient data
This is an observational study that looks at how epilepsy is diagnosed and how people do over time, using information from routine care. It may help doctors better understand epilepsy biology and outcomes using real-world data.
CardiffAges 16 years+ - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05817591Recruiting
Testing how high-dose capsaicin affects nerve pain
This study looks at what “response profiles” different people have after treatment with high-concentration capsaicin for nerve-related pain. It may help doctors predict who benefits from capsaicin by measuring changes in symptoms and nerve sensitivity.
AnnecyAges 18 years+ - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06262594RecruitingPhase 3
Testing a sleep medicine for epilepsy-related insomnia
This study tests a new sleep medicine called lemborexant for people with epilepsy whose seizures happen during sleep and who also have trouble sleeping. The goal is to see if the medicine can help you sleep better without making your seizures worse.
Durham, North CarolinaAges 18 years+ - NCT06797284Recruiting
Light, electrical, and magnetic therapy for sleep issues
This study tests if light, electrical, or magnetic treatments can help people with insomnia, narcolepsy, or REM sleep behavior disorder improve their sleep-wake problems. It compares these gentle brain stimulation methods to understand which works best.
Suzhou, JiangsuAges 8–75 - NCT06825650Recruiting
Turkish adaptation of a pain questionnaire
This study aims to adapt a questionnaire about pain into Turkish and check if it works well. Researchers want to see if the questions are understandable and reliable for people with certain types of pain.
Ankara, AltındağAges 18 years+ - NCT06826287Recruiting
7T MRI study of action watching in cerebral palsy
This study uses a very powerful 7T MRI scanner to look at how your brain responds when you watch actions. It may help doctors understand brain injury in people with cerebral palsy.
Calambrone, PISAAges 11–40 - NCT07403266RecruitingPhase 3
Full-spectrum cannabis oil for seizures in tuberous sclerosis
This trial tests a full-spectrum cannabis extract to see if it reduces seizures in people with tuberous sclerosis complex (TSC) whose seizures have not been controlled by other treatments. If it works, it could offer a new option for managing hard-to-treat epilepsy.
MadridAges 2–65 - NCT07404761Recruiting
Moving your arm after stroke or TBI
This study tests a device that uses mild electrical pulses and augmented reality (a computer overlay on real life) to help people who have arm or hand weakness after a recent stroke or brain injury regain movement.
HaifaAges 18 years+ - NCT07399171RecruitingPhase 2
Testing HT-4253 to prevent Alzheimer's in APOE4 carriers
This trial tests an experimental drug called HT-4253 to see if it can prevent Alzheimer's disease in people who are at higher genetic risk (carry the APOE4 gene) and have early signs of amyloid buildup in the brain. If you qualify, you would take the drug or a placebo and be monitored over time.
Abu Dhabi, Abu Dhabi EmirateAges 50–75 - NCT07398417RecruitingPhase 3
Testing esreboxetine for fibromyalgia relief
This study tests a medicine called esreboxetine to see if it helps people with fibromyalgia. First, everyone gets the medicine, then some may switch to a placebo to see if the medicine keeps working better than no treatment.
Glendale, ArizonaAges 18 years+ - NCT07400731Recruiting
Ear stimulation for Parkinson's symptoms
This study tests whether a device that stimulates the ear can improve Parkinson's symptoms during 'off' periods, when medication wears off. It compares how you feel before and after ear stimulation.
IstanbulAges 44 years+ - NCT07403188Recruiting
Long-Term Follow-Up Study for KYV-101 Participants
This long-term follow-up study checks on the health and safety of people who have already received the experimental cell therapy KYV-101 in a previous clinical trial. It is a way for them to be monitored over time without any additional treatments.
Denver, ColoradoAges 18 years+ - NCT07401121RecruitingPhase 1
Study of CTx1000 for people with ALS
This trial tests a new drug, CTx1000, for people with ALS. It aims to see if the drug is safe and tolerable, and may offer a new treatment option.
Sydney, New South WalesAges 18–80 - NCT07402941Recruiting
Testing inner ear stimulation during awake ear surgery
This study tests a new way to stimulate your hearing nerve during ear surgery while you are awake. It might help doctors better understand hearing loss and improve future treatments.
Cleveland, OhioAges 18 years+ - NCT07406971RecruitingPhase 2
Capsaicin nose spray for acute stroke
This trial tests a capsaicin spray applied inside the nose to stimulate a nerve cluster behind the nose, which may help improve blood flow in people having a moderate to severe stroke within the last 24 hours.
Aguascalientes, AguascalientesAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.