Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,473 recruiting studies in this area right now.
By phase
- Not applicable9,815
- Phase 2785
- Phase 1573
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia152
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California674
- Massachusetts306
- New York293
- Florida277
- Texas270
- Maryland245
- Arizona213
- Alabama212
- Illinois193
- Pennsylvania177
Recruiting studies12,471 total
- NCT07018336Recruiting
Mirror therapy vs virtual reality for arm recovery after stroke
This study compares two therapies—mirror therapy and virtual reality—to help improve arm and hand function in people who have had a stroke. It aims to find which approach works better for recovery.
Istanbul, GaziosmanpaşaAges 18–75 - NCT07018557RecruitingPhase 4
Eszopiclone for sleep and blood pressure in insomnia with high blood pressure
This trial tests if a sleep medication (eszopiclone) can lower blood pressure in people who have both insomnia and high blood pressure. You may qualify if you have trouble sleeping and your blood pressure is not well controlled despite treatment.
São Paulo, São PauloAges 30–75 - NCT07019233Recruiting
Can a pressure controller help with nerve pain from chemo?
This trial tests a device that applies real-time pressure to see if it can reduce numbness, tingling, or pain caused by a chemotherapy drug called albumin paclitaxel. It may help people starting this treatment for the first time.
TianjinAges 18–75 - NCT07019493Recruiting
Young stroke recovery study for ages 18 to 55
This study looks at how young adults recover from a stroke. Researchers want to learn more about what helps recovery in the first few months after a stroke.
Heidelberg, VictoriaAges 18–55 - NCT07019519Recruiting
Gut hormones and blood flow in POTS
This study looks at how gut hormones control blood flow after eating in people with POTS. It may help explain symptoms like dizziness and rapid heartbeat after meals.
CopenhagenAges 18–50 - NCT07019558Recruiting
Eye disorders in dominant spinal-cerebellar ataxias
This trial looks for eye problems in people with certain genetic forms of spinocerebellar ataxia (SCA1, SCA2, SCA3, or SCA27B). You have to be between 18 and 80 years old and have a specific genetic mutation. You can join if you already have symptoms or if you are at risk but do not have symptoms yet.
Montpellier, HéraultAges 18–80 - NCT07020026RecruitingPhase 2
Tau brain scan study for Parkinson's and related disorders
This study uses a special PET scan to measure tau protein buildup in the brain of people with Parkinson's disease (including those with a LRRK2 gene mutation), Progressive Supranuclear Palsy, or Corticobasal Syndrome. It aims to better understand how tau relates to these conditions.
New Haven, ConnecticutAges 45–85 - NCT07020819RecruitingPhase 3
Study of tanruprubart for people with Guillain-Barré syndrome
This trial tests a new medicine, tanruprubart (also called ANX005), for people with Guillain-Barré syndrome. It aims to see if the drug can help improve recovery when given soon after symptoms start.
Phoenix, ArizonaAges 12–85 - NCT07021040Recruiting
Nasal biopsy study for Alzheimer's and smell disorders
This study takes a small tissue sample from inside your nose to look for changes linked to Alzheimer's disease or smell problems. It may help us better understand how these conditions affect the brain.
Durham, North CarolinaAges 18 years+ - NCT07021638Recruiting
Walking training at home in virtual reality for children with chronic illnesses
This trial tests a home-based walking program using virtual reality games to help children with chronic conditions like cerebral palsy, obesity, or neuromuscular disease improve their walking and physical activity. It's designed to see if training at home with VR is effective and enjoyable.
AngersAges 6–17 - NCT07021820Recruiting
New light-based imaging for centronuclear myopathy
This study tests a new type of imaging that uses light and sound to look at muscles in people with centronuclear myopathy. It may help doctors see muscle changes more clearly. It does not involve any treatment or medicine.
Erlangen, BavariaAges 2 years+ - NCT07021859Recruiting
Migraine with aura study using CGRP to trigger attacks
This study tests whether a substance called CGRP (a protein linked to migraines) can safely trigger a migraine with aura in people who already have this condition. You'll receive an infusion and be monitored to see how your body responds.
Glostrup MunicipalityAges 18–65 - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT07022522Recruiting
Brain stimulation frequencies for impulse control in Parkinson's
This study tests whether stimulating specific parts of the brain's subthalamic nucleus at different frequencies can improve control over unwanted movements or impulses in people with Parkinson's disease. If you are planning to have DBS surgery, this trial may help find a better way to use the device.
Beijing, Beijing MunicipalityAges 40–80 - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT07022808Recruiting
Exercise program for people with spinal cord injury
This trial tests a home-based exercise program for people with spinal cord injury. You join live video exercise classes and work with a trainer to improve your strength and movement.
Philadelphia, PennsylvaniaAges 18–75 - NCT07023224Recruiting
Turkish Parkinson's Dyskinesia Scale Reliability Study
This study is testing a Turkish version of a scale that measures dyskinesias (involuntary, jerky movements caused by Parkinson's medication). If you have Parkinson's, experience dyskinesias, and are at a mild to moderate stage, you may be able to help researchers see if the translated scale works well.
Izmir, İ̇zmi̇rAges Any age - NCT07023523Recruiting
Controlling brain activity for chronic pain
This study tests if people with fibromyalgia can learn to control their own brain activity using real-time feedback from an MRI machine to reduce pain. It is designed to help those with long-term chronic pain find new ways to manage it.
Boston, MassachusettsAges 18–65 - NCT07024875Recruiting
Brain imaging study for Parkinson's disease
This study uses brain scans to understand Parkinson's disease. It compares people with Parkinson's to healthy volunteers to learn how the brain changes.
St Louis, MissouriAges 40 years+ - NCT07025005RecruitingPhase 4
Fenofibrate to prevent nerve damage from multiple myeloma treatment
This trial tests if adding fenofibrate to standard treatment (VRd) can prevent nerve damage (peripheral neuropathy) caused by bortezomib in patients with newly diagnosed multiple myeloma. If you are starting VRd therapy, this study may help reduce pain or numbness from the chemotherapy.
Damanhur, El- BehiraAges 18 years+ - NCT07025070Recruiting
Exercise and brain health in active vs. inactive adults
This study looks at how physical activity affects brain health in healthy adults. It compares people who exercise regularly with those who are not very active, to see if staying active helps keep the brain sharp.
Madrid, MadridAges 40–75 - NCT07025317Recruiting
Study on concussions and brain training in older adults
This study looks at how repeated concussions affect the brain as we age. It tests a computer-based brain training program and uses MRI scans to see if training can help improve thinking and memory.
Victoria, British ColumbiaAges 60 years+ - NCT07025694Recruiting
Exercise training for children with cerebral palsy
This study looks at whether a supervised exercise program can improve health and well-being in children with mild cerebral palsy. It compares them with typically developing children who are not already in a regular exercise routine.
Lund, Skåne CountyAges 10–16 - NCT07026253Recruiting
Delirium risk in older adults given common antibiotics
This study looks at whether certain antibiotics (ceftazidime, cefepime, or ceftriaxone) raise the chance of confusion or delirium in hospitalized adults 65 and older. The goal is to find out which antibiotic might be safest for the brain.
Alexandria, EgyptAges 65 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,473 recruiting neurology studies from the U.S. registry right now, out of 19,792 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.