Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04712591Recruiting
Testing a recovery approach for people with severe brain injury
This study is testing a recovery strategy for adults who are in intensive care after a severe brain injury and are not able to follow commands. It may help doctors learn better ways to support recovery in this critical situation.
Miami, FloridaAges 18 years+ - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04715568RecruitingPhase 4
Testing how smoke exposure affects heart health
This study looks at whether being exposed to secondhand tobacco smoke at work affects heart and blood vessel health. It may help researchers understand which people are at higher risk and how the body responds to that exposure.
San Francisco, CaliforniaAges 40 years+ - NCT04719026Recruiting
Teeth and heart attack link in people with or without heart attacks
This study compares dental health in people who were recently admitted for a heart attack with similar people who have not had a heart attack. It aims to see whether gum and dental health might be related to heart attack risk.
AberdeenAges 20–90 - NCT04722796Recruiting
TAVR for bicuspid aortic valve with a specific device
This study tests a “solution” approach using a self-expanding valve during TAVR (a less invasive way to replace a narrowed aortic valve). It aims to improve how well the valve fits and works in people with a specific heart valve shape (bicuspid aortic stenosis).
Bengbu, AnhuiAges 60 years+ - NCT04725617Recruiting
Smoking-quit program for people with HIV and sleep issues
This study tests a wellness-based smoking-cessation program (including the stop-smoking medicine varenicline) for people living with HIV who want to quit. It aims to help you reduce or stop smoking while monitoring safety, sleep, and mental health during the program.
Phoenix, ArizonaAges 18–75 - NCT04728516RecruitingPhase 4
Eradication treatment versus acid pills to prevent GI bleeding
This trial compares a “dual eradication therapy” (to get rid of H. pylori in the stomach) versus usual acid-reducing pills (PPIs) to lower the risk of gastrointestinal bleeding in people with recent heart artery disease treated with a stent. It may help by reducing stomach infection-related bleeding while you continue needed heart medicines.
Bozhou, AnhuiAges 18 years+ - NCT04731558RecruitingPhase 4
Blood clot prevention before versus after liver surgery
This study compares two approaches to preventing blood clots around the time of liver surgery. If you’re having planned liver surgery, it may help doctors choose the safest timing and method for clot prevention.
HelsinkiAges 18 years+ - NCT04735003Recruiting
Transcatheter heart procedure for tricuspid valve leaking
This trial is studying a heart procedure that is done through catheters (not open-heart surgery) to treat a leaky tricuspid valve. It may help patients who have valve leakage and are candidates for this specific catheter-based approach, and who can return for follow-up visits.
Brescia, LombardyAges 18–100 - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT04737941Recruiting
Study of treatment for leg ulcers from weak leg veins
This study looks at people with a healing or healing-worsening leg ulcer caused by weak veins (venous reflux). It may help improve care for this common type of ulcer and reduce time to healing by testing an approach for venous ulcers.
HelsinkiAges 18 years+ - NCT04741711Recruiting
At-home ultrasound to help manage heart failure
This study tests whether using lung ultrasound at regular visits can help guide care for people with heart failure. It may help doctors spot worsening fluid problems earlier, before symptoms become severe.
BesançonAges 18 years+ - NCT04743180Recruiting
Registry of a drug balloon for leg artery blockages
This study follows people with blocked blood vessels in the thigh and behind the knee to see how well a drug-coated balloon (“Luminor”) works over 5 years. It’s designed to collect real-world results and track safety and outcomes long term.
Bordeaux, New AquitaineAges 18 years+ - NCT04746534Recruiting
Study for blood-flow problems in the intestines
This study follows adults with intestinal blood-flow problems (from artery or vein issues) to better understand these conditions. It may help doctors plan future diagnosis and treatments for people with sudden or long-lasting intestinal ischemia.
ClichyAges 18 years+ - NCT04746677Recruiting
Stent repair for complex aortic problems when standard options fail
This trial tests whether a specially built stent-graft made for your anatomy can be done safely and effectively for complex aortic disease. It may help people who are too risky for open surgery or who cannot wait for a standard custom device to be made.
Boston, MassachusettsAges 21 years+ - NCT04748796RecruitingPhase 3
Landiolol to prevent death in ventilated septic shock patients
This trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can reduce deaths compared with standard care in people in septic shock who have a fast heart rate and strong heart pumping. It is meant for a very specific type of critically ill patient while they are on a breathing machine.
AmiensAges 18 years+ - NCT04747626Recruiting
Stent-based repair for damaged upper aorta segments
This trial studies a specific surgical approach using branched stents to repair multiple damaged parts of the upper (thoracic) aorta. It may help people who need urgent or complex aortic repair and are expected to survive more than two years.
Cleveland, OhioAges 18 years+ - NCT04746820Recruiting
Brain monitoring in unconscious ICU patients after cardiac arrest
This trial tests a bedside brain-monitoring method (near-infrared light and EEG) in people who are unconscious after severe brain injury from cardiac arrest. The goal is to see whether it can help measure brain function during the first week after admission.
Zurich, Canton of ZurichAges 18 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT04750616RecruitingPhase 2
NAD+ for heart injury prevention around non-emergency surgery
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
San Francisco, CaliforniaAges 18 years+ - NCT04749927Recruiting
Image-based eye photos to study heart blood-vessel risks
This study uses deep learning (computer pattern recognition) to analyze retinal photos (pictures of the eye’s blood vessels). It aims to link what’s seen in the eye to heart and blood-vessel disease patterns, especially in people with higher cardiovascular risk.
SeoulAges 20–79 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT04753840Recruiting
Remote arm conditioning and mindfulness for mild high blood pressure
This trial studies whether doing “remote ischemic preconditioning” (repeated brief conditioning of a limb) and mindfulness helps people with mild high blood pressure over the long term. It may help lower blood pressure and improve heart-related health, if you can safely do the required activities.
Zhengzhou, HenanAges 18–80 - NCT04754659Recruiting
Checking kidney function after EVAR stent graft for aneurysm
This study looks at how a stent graft treatment for an abdominal aortic aneurysm affects kidney function over time. It may help doctors choose the safest approach for people whose aneurysm is treated with a procedure called EVAR.
Gothenburg, VastraGotalandAges 18–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.