Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT02097758Recruiting
3D heart ultrasound to guide a device closure for ASD
This trial looks at whether a special 3D ultrasound picture helps doctors safely place a small device to close an atrial septal defect (ASD), a hole in the heart’s upper chambers. If you need ASD closure and are suitable for a device, the results could help improve guidance and outcomes.
SeoulAges 18–80 - NCT01372800Recruiting
Study blood adiponectin levels and stroke/heart risk
This study measures a blood marker called adiponectin and looks at how it relates to heart and stroke (cardiovascular and cerebrovascular) problems over time. It may help doctors understand who is at higher risk, especially in Chinese participants.
Xi'an, ShaanxiAges 18–85 - NCT06115759Recruiting
Recovery and activity study after open-heart surgery
This study tests a new recovery plan called T-REX to see if it helps patients feel better and get back to moving sooner after open-heart surgery. It is for people having surgery at Thorax Centrum Twente.
Enschede, OverijsselAges 18 years+ - NCT07431762RecruitingPhase 4
Aspirin vs. Warfarin after bioprosthetic valve surgery
This trial compares aspirin to warfarin in the first six months after receiving a bioprosthetic (tissue) heart valve. It aims to find which treatment better prevents blood clots without causing excessive bleeding.
OsakaAges 19 years+ - NCT07427199Recruiting
Digital nutrition therapy after heart attack
This study tests whether a digital nutrition program (app- or online-based) can improve heart function after a heart attack. It compares the program to standard care for people who have had a STEMI heart attack.
Samsun, AtakumAges 19–65 - NCT07428967Recruiting
Pacemaker after heart procedure for atrial fibrillation
This trial tests a new type of pacemaker for people with atrial fibrillation who are scheduled for a procedure that disconnects the heart's natural electrical pathway. It may help improve symptoms and heart function.
HagenAges 18 years+ - NCT07429721RecruitingEarly Phase 1
Testing QI-019A for multiple myeloma that came back
This trial tests a new drug called QI-019A for people whose multiple myeloma has returned or stopped responding to at least two prior treatments. The goal is to see if it is safe and if it can help control the disease.
Wuhan, HubeiAges 18 years+ - NCT07426484RecruitingPhase 4
Testing cosibelimab for advanced skin cancer in specific patients
This trial tests an immunotherapy drug called cosibelimab for patients with advanced cutaneous squamous cell carcinoma who have either had a kidney transplant or have a blood cancer like lymphoma or myeloma. The goal is to see if it can shrink tumors when surgery or radiation is not an option.
Boston, MassachusettsAges 18 years+ - NCT07427472Recruiting
Follow-up study of heart artery changes in familial high cholesterol
This trial follows people with a genetic high-cholesterol condition (HeFH) who had a heart scan at least 5 years ago. Researchers will do a new scan to see how their heart arteries have changed over time, without any experimental treatments.
ParisAges 30–60 - NCT07432607Recruiting
High-Flow Nasal Oxygen vs Face Mask for Heart Surgery
This trial compares two ways of giving oxygen during a heart surgery that uses small chest cuts. One method is a face mask, the other is a high-flow nasal tube. The study will see which keeps your oxygen levels better while you are awake but relaxed.
Istanbul, KARTALAges 18–75 - NCT07427511Recruiting
Rehab program for stroke recovery
This study tests a rehabilitation program for people who still have arm or leg trouble after a stroke. It aims to see if intensive daily training can improve movement and function.
Vitznau, Canton of LucerneAges 18–85 - NCT07427927Enrolling by invitation
Hemorrhoid surgery patient groups study
This study looks at people who have had surgery for hemorrhoids to find common patterns or groups among them. It may help improve care by better understanding different types of hemorrhoid disease.
San Donato Milanese, MilanAges 18 years+ - NCT07434674Recruiting
Long-Term Atrial Fibrillation After Acute Illness Study
This study is for people who recently had atrial fibrillation (an irregular heartbeat) for the first time while in the hospital or sick. It uses a small implantable heart monitor to see if the irregular heartbeat comes back over the next few years.
La Jolla, CaliforniaAges 18 years+ - NCT07431710Recruiting
AI-guided chest compressions for cardiac arrest in the ER
This trial tests whether artificial intelligence (AI) can help doctors give better chest compressions during CPR for adults whose hearts stopped outside the hospital. The goal is to improve blood flow and outcomes without using special equipment in the ambulance.
New Taipei City, BanqiaoAges 20 years+ - NCT07430553Recruiting
Comparing pacemakers for better heart function in heart failure
This trial compares three types of advanced pacemakers (cardiac resynchronization therapy devices) to see which works best for improving heart function and reducing abnormal heart rhythms in people with heart failure.
London, Greater LondonAges 18 years+ - NCT07427108Recruiting
Road map vs. ultrasound for retrograde leg angioplasty
This trial compares two imaging methods (road map vs. ultrasound) to guide a needle puncture from the ankle area during angioplasty for blocked leg arteries. It aims to see which method is safer and more effective for patients with severe leg wounds or ulcers that need this retrograde approach.
SohagAges 18 years+ - NCT07432204Recruiting
Therapeutic music listening after stroke
This trial tests whether listening to music can help reduce anxiety and depression in people who have had a stroke within the past 3 months. It is designed for those who are experiencing significant emotional distress after their stroke.
PaviaAges 18 years+ - NCT07430813Recruiting
Drone delivery of defibrillators for bystanders
This study tests if drones can deliver a defibrillator to people who witness a cardiac arrest, helping them provide lifesaving care before an ambulance arrives. You may be asked to use a training manikin to see how quickly you can help.
Guildford, SurreyAges 18 years+ - NCT07432126Recruiting
Community health workers manage high blood pressure and diabetes in Nepal
This trial tests whether community health workers can help people in Nepal better manage high blood pressure (also called hypertension) and diabetes. If you have one or both conditions, this study may help you get support closer to home.
Kavre, BagmatiAges 30 years+ - NCT07434726Recruiting
Balloon in aorta to improve CPR for in-hospital cardiac arrest
This trial tests if placing a balloon in the main artery (aorta) during CPR can improve blood flow to the heart and brain. It is for adults who have a cardiac arrest while already in the hospital and have a pulse-check showing some heart activity.
BernAges 18 years+ - NCT07433972Recruiting
Brain stimulation for walking after stroke
This study looks at whether a gentle electrical current applied to the head can improve blood flow in the brain and help with walking after a stroke. You would receive a non-invasive brain stimulation treatment during the study.
Salaya, Changwat Nakhon PathomAges 18–80 - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07428473RecruitingPhase 1
Study of STX-1150 for high cholesterol
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
Clayton, VictoriaAges 18–70 - NCT07428824Recruiting
Action observation with sound for stroke recovery
This study tests whether watching movements and listening to sounds at the same time can help improve walking and moving after a stroke. It is for people who are at least 6 months past their stroke and can already walk a bit.
Lahore, Punjab ProvinceAges 40–60
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.