Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07440316Recruiting
Colorado community health study for diverse groups
This study aims to work with Black, East African, Latino, Hispanic, or Native American communities in specific Colorado regions to improve health. It may help you by focusing on the unique needs of your community.
Aurora, ColoradoAges 18–90 - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+ - NCT07436299Recruiting
New ultrasound method for heart pressure in atrial fibrillation
This study tests a new way to use ultrasound (echocardiogram) to measure heart pressure in people who have both heart failure and atrial fibrillation (irregular heartbeat). Participants will have an ultrasound and a heart catheterization to see if the new ultrasound method can accurately detect elevated pressures.
Cleveland, OhioAges 18 years+ - NCT07435662Recruiting
Improving heart failure care in Denver
This study aims to improve heart failure treatment for people who have limited access to care in Denver. If you have heart failure with reduced pumping ability and are a patient in the Denver Health system, this trial may help find better ways to manage your condition.
Denver, ColoradoAges 18 years+ - NCT07439991Recruiting
Study of blood clot risks after lung cancer surgery
This study looks at why some people develop blood clots after lung cancer surgery. By tracking your recovery for 30 days, researchers hope to find better ways to predict and prevent clots in the future.
Changchun, JilinAges 18 years+ - NCT07436702Recruiting
Best time for treatment in serious pulmonary embolism
This trial looks at when it's best to give treatment to restore blood flow in people with a serious type of pulmonary embolism. It aims to find the optimal time for this procedure to improve outcomes.
Milan, MilanoAges 18 years+ - NCT07438613Recruiting
Ultrasound of neck vein for fluid levels in dialysis
This trial uses ultrasound to check the fluid levels in people on long-term dialysis. It aims to see if this can help doctors better adjust their treatment.
BolognaAges 18 years+ - NCT07438379Enrolling by invitation
Reproductive Health Study for Pregnant Women in Somaliland
This study explores reproductive health in women living in Somaliland who are in early to mid-pregnancy. The goal is to learn more about health needs and experiences during pregnancy.
Hargeisa, MaroodijeehAges Any age - NCT07436429Recruiting
Drug-coated balloon for heart attack treatment
This trial tests if a special balloon that releases medication can be used instead of a stent during emergency angioplasty for certain heart attacks. It may help patients who are having a first-time heart attack and are stable enough for the procedure.
ViennaAges 18 years+ - NCT07435727Recruiting
Comparing Two Steps to Remove Tracheostomy in Stroke Patients
This trial compares two methods (a speaking valve trial vs. a capping trial) to help stroke patients with a tracheostomy safely remove their trach tube. It tests which method works better to prepare you for breathing on your own.
Beijing, Beijing MunicipalityAges 18–80 - NCT07444398RecruitingPhase 1
Vericiguat for worsening heart failure
This trial tests if adding vericiguat to standard heart failure medicines helps people hospitalized with worsening heart failure. It's for those with a weak heart pump and high NT-proBNP levels.
Rawalpindi, Punjab ProvinceAges 25–65 - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07436962Recruiting
Loop recorder for mitral valve heart condition
This trial tests whether a small heart monitor (loop recorder) can help people with a specific mitral valve condition called mitral annular disjunction. It's for patients who have scar tissue in their heart muscle shown on an MRI.
BudapestAges 18–60 - NCT07437222Recruiting
Ginger capsules for inflammation in overweight adults
This study tests whether taking ginger capsules can help reduce inflammation, oxidative stress, and improve blood vessel function in people who are overweight or obese but otherwise healthy. You would take ginger capsules daily for several weeks and have your blood and blood vessel health checked.
Murcia, MurciaAges 23–65 - NCT07439965Recruiting
Studying blood particles from different body areas in aneurysm patients
This trial looks at tiny particles in the blood called extracellular vesicles to see how they differ in patients with brain aneurysms. It may help doctors better understand these aneurysms and improve treatment.
Changchun, JilinAges 18–60 - NCT07440667Recruiting
Fluid amounts during planned C-section and recovery
This trial compares giving less fluid versus more fluid during planned C-section surgery to see which approach leads to better recovery afterward.
Niğde, MerkezAges 18–45 - NCT07441057Recruiting
Studying a therapy for arm movement in kids with stroke
This study tests whether a therapy called CHRIST can help children who've had a stroke improve the movement and function of their affected arm and hand.
Mandi Bahāuddīn, Punjab ProvinceAges 7–12 - NCT07444151Recruiting
Post-stroke fatigue perception study
This study explores fatigue after stroke. If you have ongoing tiredness that you believe stems from your stroke, researchers want to learn from your experience through a questionnaire.
Carouge, Canton of GenevaAges 18 years+ - NCT07444138Recruiting
Beetroot extract for blood pressure and exercise in older women
This study tests whether drinking beetroot extract can help lower blood pressure and improve exercise ability in older women with high blood pressure. It compares beetroot extract to a placebo (a drink with no active ingredient) while participants do light physical activities.
Bauru, São PauloAges 60 years+ - NCT07439380Recruiting
Group care for high blood pressure and diabetes in Nepal
This trial tests whether group-based care can help people manage high blood pressure or diabetes better than standard care. If you live in one of the study areas in Nepal and have high blood pressure or diabetes, you may be able to join.
DhulikhelAges 18 years+ - NCT07442448Enrolling by invitationPhase 4
Study of Finerenone for heart and kidney health in diabetes
This trial tests a medication called Finerenone to see if it can improve heart structure and function in people with both diabetic kidney disease and heart failure. If you have type 2 diabetes, kidney problems, and heart failure with preserved pumping function, this study may explore a new treatment option for you.
TaipeiAges 18 years+ - NCT07444047Recruiting
MRI study of brain lesions in older MS patients
This study uses MRI scans to compare brain lesions in older patients with multiple sclerosis versus those with small vessel disease. It aims to improve how doctors tell apart these conditions and may lead to better treatment choices.
Oslo, OsloAges 50–80 - NCT07438938Recruiting
Lazarus airway opening index trial for cardiac arrest
This study looks at a new measure called the Airway Opening Index (AOI) to see if it can help doctors predict when a person's airway opens during CPR after a heart attack outside the hospital. If you've had a cardiac arrest and needed a breathing tube, this research might help improve how care is given.
Ghent, East-FlandersAges 18 years+ - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.