Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07387575Enrolling by invitation
Screening for brain aneurysms in high-risk family members
This study uses a special MRI scan to look for unruptured brain aneurysms in people who have a close family member who had a bleeding aneurysm. It aims to find aneurysms early in those who smoke or have high blood pressure.
Novi Sad, VojvodinaAges 18 years+ - NCT07380243Recruiting
Food for Health: A Prevention Trial for Families
This trial tests if giving healthy food to families can improve health and prevent disease. It's for parents with a high BMI who have a child between 6 and 11 years old.
Columbus, OhioAges 6 years+ - NCT07387393Enrolling by invitation
PILI Pasifika Lifestyle Program for Native Hawaiian and Pacific Islander adults
This study tests a 3-month lifestyle program called PILI Pasifika, which includes healthy eating, physical activity, and support for social needs like housing or food. It aims to help Native Hawaiian and Pacific Islander adults with conditions like diabetes or high blood pressure improve their health in real-world settings.
Fayetteville, ArkansasAges 18 years+ - NCT07385092Recruiting
Continuous monitoring after non-cardiac surgery
This trial compares continuous vital sign monitoring with standard spot checks for patients recovering from non-cardiac surgery. It aims to see if constant monitoring can improve safety and outcomes.
Hamburg, Free and Hanseatic City of HamburgAges 45 years+ - NCT07387328Recruiting
Testing new sensor placement for leg muscles in stroke survivors
This study checks if new guidelines for placing sensors on leg muscles work well in people who have had a stroke. It could help improve how we measure muscle activity during walking and other movements.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06313866Recruiting
Herbal sniffing therapy plus acupuncture for stroke-related thinking problems
This trial tests if combining traditional Chinese herbal sniffing therapy with electroacupuncture can improve memory and thinking after a stroke. It may help people who are still in the early recovery phase.
Hangzhou, ZhejiangAges Up to 70 years - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06836986Recruiting
Norepinephrine vs. phenylephrine for blood pressure in C-section
This trial compares two medications, norepinephrine and phenylephrine, to see which works better at preventing low blood pressure during emergency C-sections under spinal anesthesia.
Karachi, SindhAges 18–40 - NCT06838637Recruiting
Spinal cord stimulation at home for blood pressure issues
This trial tests using a gentle electrical device on your spine at home to help with dizziness from low blood pressure (orthostatic hypotension). It is for people with chronic spinal cord injury or multiple system atrophy who live in British Columbia.
Vancouver, British ColumbiaAges 19–70 - NCT05004610RecruitingPhase 2
Hypertonic lactate treatment after cardiac arrest
This trial studies whether giving a specific IV fluid (hypertonic lactate) soon after resuscitation from cardiac arrest can improve recovery. It is for adults who remain in a deep unresponsive state after return of spontaneous circulation.
Brussels, BelgiumAges 18 years+ - NCT05886517Recruiting
Transcatheter aortic valve in patients too high-risk for surgery
This trial looks at placing a new aortic valve through the groin (transfemoral) without needing on-site heart surgery for people who are considered very high risk for standard open-heart valve surgery. It aims to measure early outcomes to see how safe and effective this approach is for frail or complex patients.
Acquaviva delle Fonti, BariAges 75–120 - NCT05629559RecruitingPhase 1/Phase 2
Study drug 4D-310 for Fabry disease with heart problems
This Phase 1/2 study tests how safe and potentially effective 4D-310 is for adults with Fabry disease who have heart involvement. It may help people who can’t tolerate standard treatments like enzyme replacement therapy (ERT) or migalastat, or who still have disease progression.
MelbourneAges 18–65 - NCT06075433Recruiting
One year of blood thinners after a GENOSS stent for heart disease
This study tests whether taking two blood thinners for one year after getting a special GENOSS stent is safe and works well for people with coronary artery disease, especially if the stent placement was complex. The goal is to prevent blood clots and keep your artery open.
Wŏnju, Gangwon StateAges 19 years+ - NCT06075420Recruiting
Shorter blood thinner use after GENOSS stent in heart disease
This trial tests whether a shorter course of dual antiplatelet therapy (two blood thinners) is safe and effective for people who have received a GENOSS stent for coronary artery disease. It aims to reduce the risk of bleeding while still preventing heart attacks.
Wŏnju, Gangwon StateAges 19 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+ - NCT06738381Recruiting
Digital prevention program after heart attack or stroke
This trial tests a digital program (using a smartphone or tablet) to help prevent another heart attack or stroke. It is for people who have already had a heart-related event or have known artery plaque buildup.
Drammen, BuskerudAges 18 years+ - NCT06823778Recruiting
Preventing irregular heartbeat after heart surgery with radiofrequency
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
Moscow, MoscowAges 18 years+ - NCT06839755Recruiting
Stress echo's positive value in heart health
This study looks at how well a stress echocardiogram (heart ultrasound during exercise or medication) predicts future health in people who have some sign of reduced blood flow to the heart. The goal is to confirm that a positive stress echo is a good sign for guiding next steps.
Athens, AtticaAges 18–100 - NCT06839404Recruiting
Fluid bolus effect on heart and blood flow
This study looks at how a standard IV fluid bolus affects blood flow and heart function in ICU patients. It aims to better understand the body's response to this common treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT07375433Recruiting
Heart failure and COPD study for patients aged 50 to 70
This trial looks at how heart failure with preserved pumping function affects people who also have COPD. It aims to understand the course of the disease and long-term outlook.
Kazan'Ages 50–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.