Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05585411Recruiting
Pacemaker type test to reduce heart worsening and death risk
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
Bucheon-siAges 19 years+ - NCT05586282Recruiting
Study proteins that may worsen fluid leaks in shock
This trial studies specific body proteins to understand why fluid can leak from blood vessels during dangerous shock after infection or heart problems. If you (or your representative) qualify, your team will collect information and possibly samples to see whether these proteins relate to recovery and treatment response.
ParisAges 18 years+ - NCT05588024Recruiting
Device-assisted CPR with head and chest elevation during arrest
This trial studies a CPR method that uses a device to help raise the head and chest during active resuscitation after cardiac arrest. It may help guide whether this technique improves outcomes for people who are not breathing normally and do not have a pulse.
Minneapolis, MinnesotaAges 18 years+ - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT05590871Recruiting
Kidney nerve ablation to treat hard-to-control blood pressure
This trial tests a procedure that targets nerves near the kidney (renal denervation) to help lower blood pressure in people whose hypertension is not controlled despite medication. It uses a special 3D mapping system to guide the procedure.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05591196Recruiting
Electrical spinal stimulation to improve arm movement after stroke
This study tests a non-invasive electrical stimulation treatment meant to help people regain hand and arm movement after a stroke. You would attend frequent therapy-style sessions, and the team would track your arm function over about eight months.
Seattle, WashingtonAges 21–80 - NCT05591118RecruitingPhase 3
Catheter treatment to remove blood clots in the lungs
This Phase 3 trial tests a catheter-based procedure to remove a lung blood clot (pulmonary embolism) and reduce strain on the heart. It may help people who have specific CT scan signs of right-heart strain.
Birmingham, AlabamaAges 18 years+ - NCT05591040Recruiting
Biofeedback to help swallow problems after stroke
This trial studies whether using “biofeedback” (seeing your body’s muscle signals on a screen) along with standard care can improve swallowing after a stroke. You might be eligible if you have ongoing swallow trouble and can safely do the training sessions.
Venice-LidoAges 18–89 - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05593679Recruiting
Registry study for heart PYP scans in possible ATTR amyloidosis
This study collects information from adults who have been diagnosed with, or are being checked for, ATTR amyloidosis (a condition where abnormal protein builds up in the body) using a heart PYP scan. Your participation may help doctors better understand how these scans relate to diagnosis and follow-up over time.
New Taipei CityAges 20 years+ - NCT05594797RecruitingPhase 2
BCMA CAR-T for multiple myeloma that came back or stopped working
This trial tests a one-time BCMA CAR-T cell treatment for people with multiple myeloma that relapsed or did not respond well to prior treatments. It may help by training your own immune cells to recognize and attack myeloma cells.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05595668Recruiting
Home computer therapy for brain neglect after stroke
This trial tests an at-home, phone/computer-based therapy to help people who have “neglect” after a stroke, using visual tasks to retrain attention. It may help improve how you notice and respond to the space on one side of your world.
Bedford, Nova ScotiaAges Any age - NCT05596773Recruiting
Village health worker program for chronic disease care in Lesotho
This study tests a community-based care approach using trained village health workers to support people with chronic (long-term) health conditions. It may help your village get easier access to ongoing support, using a tablet-based tool and coaching from health professionals.
MaseruAges Any age - NCT05597345RecruitingPhase 2
Selinexor for higher-risk smoldering myeloma
This trial studies selinexor, a medicine taken by mouth, to slow or treat intermediate- or high-risk smoldering multiple myeloma before it becomes symptomatic. It may help some people reduce disease progression, based on how well the treatment controls the abnormal plasma cells.
Rochester, New YorkAges 18 years+ - NCT05598879Recruiting
New heart-cancer visit registry for adults
This study is a “registry,” meaning it collects health information from adults who are getting a new heart (cardio) evaluation related to cancer. It helps doctors better understand heart risks and care needs for different cancer types and treatments.
Weston, FloridaAges 18 years+ - NCT05599022Recruiting
Testing TcMS to stop dangerous fast heart rhythms
This trial tests a treatment called TcMS to reduce episodes of dangerous fast heart rhythm (VT) or shocks from an implanted heart device. It may help people who keep having these episodes even after taking at least one anti-arrhythmia medicine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT05599438Recruiting
Fitness and drug use study in recreational athletes
This study follows recreational athletes to understand how past and current anabolic-androgenic steroid (AAS) use relates to fitness changes over time. If you have used these substances in the past (and stopped more than 3 months ago), or you have never used them, you may be able to join.
CopenhagenAges 18 years+ - NCT05600374Recruiting
Brain stimulation timed to brain rhythms after recent stroke
This trial tests a special brain-stimulation approach that targets your brain’s natural 8–12 Hz rhythm to improve arm and hand recovery after stroke. It’s designed for people in the early days after an ischemic stroke, when motor recovery is still changing quickly.
Frankfurt a.M., Frankfurt a.M.Ages 18 years+ - NCT05602363RecruitingPhase 1
Docirbrutinib for CLL or lymphoma after prior treatments
This Phase 1 study tests docirbrutinib, a targeted pill treatment, in people with CLL/SLL or certain other B-cell lymphomas that have come back or didn’t respond to earlier therapy. The goal is to see whether it’s safe and whether it can control the disease after standard treatments have failed.
Orange, CaliforniaAges 18 years+ - NCT05603026Recruiting
MRI study for people getting a valve replacement
This study uses MRI (a type of scan) in people who are scheduled for a catheter-based aortic valve replacement through the groin. It aims to see how well MRI can work for these patients and potentially improve care planning around the procedure.
Cleveland, OhioAges 18–105 - NCT05603520Recruiting
Study of how the aorta varies in healthy people and patients
This study uses MRI scans to understand how different parts of the aorta look and behave, including in healthy volunteers and people with aortic problems. It may help researchers better describe differences in the aorta that could improve future diagnosis or treatment planning.
DüsseldorfAges 18 years+ - NCT05604638RecruitingPhase 3
Tirofiban soon after tenecteplase for acute stroke flare
This trial tests whether starting tirofiban soon after tenecteplase can improve outcomes for people whose stroke symptoms temporarily get worse after treatment. It aims to see if the added medicine can reduce harmful clot-related changes after initial thrombolysis.
Chuzhou, AnhuiAges 18 years+ - NCT05606809Recruiting
Score brain injury after cardiac arrest ICU admission
This study compares different scoring methods to estimate early brain injury when people are admitted to the ICU after a cardiac arrest. It may help doctors choose the best early assessment approach for patients who are in a coma.
Nantes, Pays de LoireAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.