Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07304817RecruitingPhase 2
Comparing two heart and kidney medicines in heart failure
This study tests if a new medicine (vicadrostat) works differently than an older one (spironolactone) in people with heart failure or heart disease and reduced kidney function. It aims to understand how they affect proteins in the blood and kidney blood flow.
Groningen, Provincie GroningenAges 18 years+ - NCT07299812Recruiting
Protecting the heart during breast cancer radiation
This trial tests whether a special breathing technique (called Active Breathing Coordinator) can help keep radiation away from the heart while treating breast cancer with radiation therapy. If you can hold your breath briefly during treatment, this might lower the risk of heart damage.
Pavia, LombardyAges 18 years+ - NCT07304193Enrolling by invitation
Study of sex chromosome disorders in fetuses
This study looks at the genetics of fetuses with sex chromosome disorders. It compares them to fetuses without these conditions to understand more about how these disorders affect development.
AarhusAges 3 months–5 months - NCT07299227Recruiting
Study on heart and lung effects of BPA in CTEPH
This study uses special heart scans (CMR with 4D flow) to see how a procedure called BPA affects blood flow in the heart and lungs for people with a rare type of high blood pressure in the lungs (CTEPH). It may help doctors understand how well BPA works beyond just symptoms.
Bad Nauheim, HesseAges 18–99 - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT07302971Recruiting
Telemedicine for stroke care in Chinese hospitals
This study tests if connecting smaller hospitals with stroke experts through telemedicine improves treatment for people having an acute ischemic stroke. It may help you get faster, better care if you live in a less populated area.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07305389Recruiting
Music and exercise in cardiac rehab
This study tests how different types of music affect your mood during exercise in a cardiac rehabilitation program. It may help make your rehab workouts more enjoyable.
GenevaAges 50–75 - NCT07298213Recruiting
Corazones Unidos Study for liver health
This study looks at whether having a family member or close friend join you can help improve liver health in Mexican-origin adults with fatty liver disease. You and your support person will participate together.
Tucson, ArizonaAges 18 years+ - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT07297641Recruiting
Imaging-guided vs X-ray-guided PCI for blocked stents
This trial compares two ways to guide a procedure to reopen a stent that has narrowed again: using a special camera inside the artery (IVUS) versus standard X-ray (angiography). It aims to see which approach works better for people who have a drug-eluting stent that is narrowing for the first time.
Nanjing, JiangsuAges 18–80 - NCT07303816RecruitingPhase 4
Can statins prevent blood clots in cancer patients?
This trial tests whether a daily statin (rosuvastatin) can help prevent dangerous blood clots in people with advanced cancer who are starting new cancer therapy. It is for those at medium or high risk for clots, based on a simple risk score.
Irvine, CaliforniaAges 18 years+ - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+ - NCT07305337Recruiting
AI health education for blood cancer patients
This trial tests if an artificial intelligence (AI) program can help people with blood cancer learn about their condition and treatment. The goal is to see if AI-assisted education improves their understanding and care.
Wuhan, HubeiAges 18–90 - NCT07305116RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a new immune therapy called CAR T-cells that target two proteins (CD19 and BCMA) to treat autoimmune diseases like lupus, nephrotic syndrome, and others. It is for people whose standard treatments have not worked well enough.
Hangzhou, ZhejiangAges 3 years+ - NCT07302009Recruiting
Cooling treatment for brain hemorrhage patients
This trial tests a bladder-based cooling device to see if it can safely control fever in patients with a new brain hemorrhage. It may help prevent further brain injury and improve recovery.
Nanchang, JiangxiAges 18–85 - NCT07298694Enrolling by invitation
Choosing a hypertension medication with helpful defaults
This trial tests whether changing the default options in doctors' ordering systems can help patients get the best medication for high blood pressure. You may be eligible if you are an adult who recently received a prescription for a common blood pressure drug at a participating clinic.
Danville, PennsylvaniaAges 18 years+ - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT06878105Recruiting
Blood management study for surgical patients
This study looks at how hospitals manage your blood during and after planned surgeries that have a moderate to high risk of bleeding. It aims to find better ways to reduce blood loss and the need for transfusions.
BudapestAges 18 years+ - NCT04524637Recruiting
Testing a clotting test in recent traumatic brain injury
This trial tests whether a special blood clotting test called thromboelastography can help assess clotting problems after a head injury. It may help doctors better understand bleeding risk and related complications early after trauma.
ShanghaiAges 18–80 - NCT04029337Recruiting
Transcatheter mitral valve replacement for severe leakage
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
Tucson, ArizonaAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT06588244Recruiting
Registry for chest pain with open arteries
This study is looking at people who have chest pain or shortness of breath but whose heart arteries look fairly open on an angiogram. It aims to understand why they have symptoms and how to improve care. You may qualify if you're having a coronary angiogram and it shows no major blockages.
Naples, ItalyAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.