Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05608317Recruiting
Track healing of draining leg ulcers with a foam dressing
This study follows how a non-bordered foam dressing helps chronic leg ulcers that leak fluid (exuding). It mainly aims to see how the wound changes over time, and whether the dressing is comfortable and effective along with standard care.
San Francisco, CaliforniaAges 18 years+ - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+ - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT05610215Recruiting
Hybrid or catheter ablation for atrial fibrillation in hypertrophic heart
This trial compares two procedures to treat atrial fibrillation (an irregular heartbeat) in people who also have hypertrophic cardiomyopathy (thickened heart muscle). It looks at whether the hybrid approach or a catheter-based approach works better for controlling symptoms and heart rhythm.
BeijingAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Mobile, AlabamaAges 18–79 - NCT05610631Recruiting
Switzerland heart-lung pressure registry for people with PH
This is a registry that collects information from people who have pulmonary hypertension (high blood pressure in the lungs). It helps researchers better understand the condition and may support future studies.
ZurichAges Any age - NCT05610865RecruitingPhase 1
Stem cell treatment for chronic diabetic foot ulcers
This Phase 1 study tests whether stem cells taken from fat tissue (after a small procedure) can help heal a long-lasting diabetic foot ulcer. It mainly aims to help ulcers that are limited to soft tissue and have good blood flow to the foot.
Lahore, Punjab ProvinceAges 20–60 - NCT05611268Recruiting
Pentoxifylline added for Eisenmenger syndrome
This study tests whether adding pentoxifylline to usual care can improve health outcomes in people with Eisenmenger syndrome. It may help reduce problems related to blood flow and vessel function, especially for those not recently hospitalized.
São PauloAges 10–80 - NCT05612945Recruiting
High-intensity versus easier walking exercise for PAD symptoms
This study tests whether harder interval exercise works better than easier, moderate exercise to improve walking symptoms in people with peripheral artery disease (PAD). It may help you compare which exercise level improves your ability to walk comfortably.
Lausanne, Canton of VaudAges 18 years+ - NCT05613985Recruiting
Ultrasound light added to usual care for infected diabetic foot ulcers
This trial tests whether adding the VULNOFAST Plus/VULNOLIGHT system to usual care can heal infected diabetic foot ulcers more safely and effectively. It compares the added treatment plus usual care versus usual care alone.
ArezzoAges 18 years+ - NCT05614193Recruiting
Deep imaging study for suspected stroke patients
This trial studies an advanced way to analyze CT or MRI scans for people who may have had a stroke or reduced blood flow to the brain. It aims to improve how scans are interpreted and shared for better care.
Beijing, Beijing MunicipalityAges 18–100 - NCT05617326Recruiting
Ultrasound screening for abdominal aortic aneurysm in general practice
This study checks whether a portable ultrasound scan in a regular doctor’s office can find abdominal aortic aneurysms (a bulge in a major artery in the belly) early. It may help identify people at risk so doctors can plan next steps sooner.
LyonAges 50–75 - NCT05617456Recruiting
Test new ablation technology for treating irregular heart rhythm
This study tests advanced technology to improve how atrial fibrillation (AFib) is treated with a heart ablation procedure. It may help patients who are already advised to have AFib ablation by seeing how well the approach works in real clinical practice.
PisaAges Any age - NCT05617599Recruiting
Checks safety of a stent used in complex heart artery disease
This study looks at how safe and effective a specific stent (SUPRAFLEX CRUZ) is when used in real-world care for people with heart artery blockages in more than one artery. Some participants will also be selected if their heart pumping strength is reduced.
Elche, AlicanteAges 18 years+ - NCT05618041Recruiting
CAR-T treatment trial for relapsed or hard-to-treat blood cancers
This trial studies whether a CAR-T cell therapy is safe and effective for people with relapsed or refractory lymphoma, leukemia, or myeloma whose tumors have the right target markers. You may qualify if your health (heart, lungs, kidneys, liver) and blood counts are within required limits.
Taiyuan, ShanxiAges 14–75 - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Birmingham, AlabamaAges 18 years+ - NCT05618990Recruiting
Trying optimized MRI scans for clearer imaging
This study tests improved MRI scan settings to get clearer images. You may be able to take part if you’re able to safely have an MRI and you meet basic study consent and contraception rules.
ParisAges 18 years+ - NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT05620095Recruiting
Drug-coated balloon angioplasty for lower leg artery blockages
This trial tests whether a drug-coated balloon can better reopen blocked arteries in the lower leg (below the knee). It may help keep blood flow open and reduce the chance the blockage comes back, after a procedure to cross and open the narrowed area.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05620186Recruiting
Training program for endovascular simulation skills
This is a study that tests a step-by-step training approach for surgical trainees using a simulator. It may help improve how trainees build knowledge and technical skills before working on real procedures.
GhentAges 18 years+ - NCT05620030Recruiting
Testing care plans for single-heart (univentricular) defects
This study follows people with a single-ventricle (univentricular) heart defect who need a multi-step treatment leading to the Fontan procedure. It aims to better understand how this staged care should be delivered and monitored over time.
ErlangenAges 6–60 - NCT05621460Recruiting
Water carbonation and how well you tolerate standing up
This study tests whether drinking carbonated (fizzy) water changes how well your body handles standing up without feeling faint. If you are healthy and don’t have certain heart or nerve problems, you may be able to take part.
Burnaby, British ColumbiaAges 19–50 - NCT05622461Recruiting
Recovery support program for children after traumatic brain injury
This trial supports families during the early weeks after a child’s brain injury and hospital stay. It aims to help caregivers and children move toward recovery with better support after discharge.
Cincinnati, OhioAges 18 years+ - NCT05623137Recruiting
Acu-TENS to improve sleep after stroke
This trial tests a non-drug treatment (Acu-TENS) that uses gentle electrical stimulation on the skin to improve sleep in people who had a stroke. It may help if you have ongoing poor sleep and meet the age, walking, thinking, and health-skin safety requirements.
Hong KongAges 55–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.