Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05638464Recruiting
Brain stimulation to help hand movement after stroke
This trial studies whether a noninvasive brain stimulation technique can improve hand and arm function in people whose stroke happened more than 12 months ago. It may help if you have mild-to-moderate hand weakness and can follow training instructions.
Hong KongAges 18 years+ - NCT05638841Recruiting
Study of repeat atrial fibrillation risk after ablation
This study follows adults who have had a procedure to treat an irregular heartbeat, to understand who is more likely to have it return. It may help doctors predict risk and plan follow-up after the procedure.
BeijingAges 18 years+ - NCT05640102Recruiting
Study of zanubrutinib in Waldenström macroglobulinemia
This is an observational study that follows people with Waldenström macroglobulinemia (WM) to learn how well zanubrutinib works and how safe it is. Your results will be tracked in relation to your disease features, including a blood/marrow marker called MYD88.
Huntsville, AlabamaAges 18 years+ - NCT05640752Recruiting
Testing whether better heart imaging planning reduces scans
This trial studies the best way to decide when people need heart imaging tests, with the goal of doing fewer unnecessary scans. It may help patients by avoiding extra radiation and tests while still keeping care safe and appropriate.
Beijing, Beijing MunicipalityAges 30–90 - NCT05641662Recruiting
Video games that get you moving for heart failure inactivity
This study tests whether playing “exergames” (motion-based video games) can help people with heart failure who are mostly inactive spend less time sitting. It checks whether the games are safe and practical and whether they can improve activity over time.
PortoAges 18 years+ - NCT05641142Recruiting
Testing blood thinners in adults with inherited bleeding vessel disease
This study looks at people with Rendu-Osler (hereditary hemorrhagic telangiectasia) who have just started blood-thinning medicines. It aims to understand how antiplatelet and/or anticoagulant therapy affects safety and outcomes soon after starting.
AngersAges 18 years+ - NCT05642884Recruiting
Pre-surgery program for older adults getting stem cell transplant
This study checks whether a “pre-surgery” health coaching program is practical and safe for older people with multiple myeloma who are scheduled for an autologous stem cell transplant. It may help patients prepare better for transplant recovery, and the study will see if the plan can be carried out smoothly.
Birmingham, AlabamaAges 60 years+ - NCT05642858Recruiting
Learn heart health tips for people living with HIV
This study tests a text-message education program to help people living with HIV manage cardiovascular (heart and blood vessel) health. It may be helpful if you are 40 or older and can use a smartphone to receive messages.
San Francisco, CaliforniaAges 40 years+ - NCT05643209Recruiting
Mapping and ablation to treat abnormal heart electrical signals
This study uses detailed 3D heart mapping to find where abnormal electrical activity starts in Brugada syndrome and then performs ablation (a targeted scar or block). It’s mainly for adults who have had concerning symptoms and already have an implanted defibrillator (ICD).
Cotignola, RavennaAges 18 years+ - NCT05643235Recruiting
Loop monitor to watch heart rhythms when starting a BTK inhibitor
This study checks how often abnormal heart rhythms happen when you start a BTK inhibitor (used for certain blood cancers). It uses a small implanted heart monitor to record your rhythm continuously before and after starting the medication, so doctors can detect and manage problems early.
New Hyde Park, New YorkAges 18 years+ - NCT05643651RecruitingPhase 4
Rivaroxaban for kids with large heart artery aneurysms after Kawasaki disease
This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT05644522Recruiting
At-home brace study for leg support and walking
This study tests an at-home wearable activity monitor and brace-related walking support for people who already use a knee-ankle-foot brace. It may help researchers understand how brace use and day-to-day movement relate to walking ability.
Chicago, IllinoisAges 18–89 - NCT05644314Recruiting
Drug-coated stent for narrowed vertebral arteries
This trial studies whether a drug-coated stent placed in a narrowed vertebral artery can improve outcomes for people with artery narrowing from plaque. It also looks at how safe the stent is, since it requires specific blood-thinning medicines around the procedure.
Guangzhou, GuangdongAges 18 years+ - NCT05644548Recruiting
Eye scan study for people with common health conditions
This study uses a special eye scan (OCTA) to look at how blood vessels in the retina change in people with conditions like high blood pressure, diabetes, or abnormal cholesterol. It may help doctors better understand how these common illnesses affect the eyes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05645510Recruiting
Study for people on long-term cancer targeted medicines
This study looks at people who are already taking long-term targeted cancer medicines. It may help researchers understand how these treatments work over time and whether there are ways to improve care.
Edmonton, AlbertaAges 18–90 - NCT05645081Recruiting
Blood test study to predict stroke risk after TIA
This trial studies tiny particles in your blood (called extracellular vesicles) to understand and predict stroke risk after a TIA (a temporary stroke-like episode). It may help doctors identify who is at higher risk using blood samples, rather than only symptoms and scans.
Merthyr TydfilAges 18 years+ - NCT05646381RecruitingPhase 2
Drug study to slow hardening of aortic valve disease
This Phase 2 trial tests pelacarsen (TQJ230), a medication that lowers a blood fat called lipoprotein(a), to see if it slows progression of calcific aortic valve stenosis. It may help people whose valve narrowing is starting to become more severe, especially when their lipoprotein(a) level is high.
Huntsville, AlabamaAges 50–80 - NCT05646394Recruiting
Registry for blood-clot prevention plans in arterial antiphospholipid syndrome
This study keeps a registry to follow people with antiphospholipid syndrome (APS) who have had arterial blood clots (like stroke). It collects information about the treatment approach your clinician chooses to see how different antithrombotic regimens may perform and be tolerated.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT05646576Recruiting
Palliative care support during blood cancer cell therapy
This trial studies whether adding palliative care (comfort-focused care to reduce stress and symptoms) helps people during adoptive cell therapy for blood cancers. It may help improve quality of life while you’re receiving the therapy.
Boston, MassachusettsAges 18 years+ - NCT05646849Recruiting
App-based support to keep exercising after heart rehab
This study tests whether a phone app can help people keep up physical activity after cardiac rehabilitation. If you can use a smartphone and internet, the app support may make it easier to stay active after your rehab program.
CholetAges 18 years+ - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05647876Recruiting
Study how menopause affects heart health risk over time
This study follows people through menopause to better understand how the body changes and how that may affect heart health risk. You may be asked for health checks over time, as researchers look for factors that increase or protect against heart problems.
CopenhagenAges 40–61 - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05649670Recruiting
Compare starting stroke clot-busting before vs after hospital
This study tests whether starting clot-busting treatment by the emergency team before hospital arrival works better than starting it after you reach the hospital. It may help doctors improve speed and outcomes after an acute stroke.
GarchesAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.