Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06880575Recruiting
Registry for seniors with coronary heart disease (SILVER-China)
This registry study in China is following older adults (75+) with coronary heart disease to learn more about their health over time. It involves sharing your medical information and coming back for check-ups, but no experimental treatments are given.
Beijing, Beijing MunicipalityAges 75 years+ - NCT05777447Recruiting
Study for infected aorta/iliac aneurysm after in-place repair
This study looks at treatment outcomes for people whose aorta or iliac artery aneurysm became infected (a “mycotic” aneurysm) and who were treated with an in-place repair. It may help doctors understand the best way to manage this rare condition after surgery.
Roma, RMAges 18 years+ - NCT05777460Recruiting
Testing custom-made devices for the thoracic aorta
This trial looks at the longer-term results of custom-made devices placed in the thoracic aorta (the main blood vessel in the chest). It may help patients learn how well these tailored devices work over time.
Roma, RMAges 18 years+ - NCT06186973Recruiting
Fetal and newborn heart assessment during labor
This study checks how well a baby's heart works during labor and right after birth. It uses a special monitor (CTG with STAN) to see if the baby's heart responds normally to the stress of labor.
OsloAges birth–1 hour - NCT06740396Recruiting
Depression in heart disease patients in Baghdad
This study looks at how common depression is in people with coronary artery disease and how severe it is. If you have heart disease and are being treated at a hospital in Baghdad, you can help doctors understand the link between heart health and mental health.
BaghdadAges 18 years+ - NCT06877195Recruiting
Vein graft support mesh for bypass surgery
This trial tests a mesh wrap that supports the vein grafts used in bypass surgery. It may help those grafts stay open longer, especially for the right side of the heart.
Roma, RomaAges Any age - NCT06813989Recruiting
Carotid Blood Flow in Pregnant Women
This study measures blood flow in the carotid artery (a major neck artery) during pregnancy and cesarean delivery. It aims to understand how pregnancy affects blood flow, which may help improve care for mothers.
IstanbulAges 20–40 - NCT06859047Recruiting
Comparing heart ultrasound to invasive testing
This study compares results from an invasive heart test (hemodynamic assessment) with a non-invasive ultrasound (echocardiogram) done on the same day. It aims to see if the ultrasound can provide similar information, potentially reducing the need for invasive procedures.
BariAges 18 years+ - NCT06880978Recruiting
Comparing two stent methods for Y-shaped heart blockages
This study compares two stent-placing techniques for people with a specific type of complex heart blockage at a branch point. It aims to see which method is safer and more effective for opening up the artery.
IstanbulAges 18 years+ - NCT04016545Recruiting
Low-profile stent devices for elective TEVAR
This trial studies whether using newer, smaller “low-profile” devices during TEVAR can affect outcomes like complications and survival. If you need an elective TEVAR, this may help doctors compare safety and results with these newer tools.
Roma, RMAges Any age - NCT05569382RecruitingPhase 4
Testing bisoprolol and verapamil in hypertrophic heart disease
This study tests whether two common heart medicines, bisoprolol and verapamil, improve symptoms in adults with non-obstructive hypertrophic cardiomyopathy. It may help you and your care team understand which medicine works better for symptom control and heart function.
Aarhus NAges 18 years+ - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT07281040Recruiting
Online discussion about heart failure treatment experiences
This study brings together people who have recently been in the hospital for heart failure and their caregivers to talk in small online groups about their experiences. The goal is to help doctors learn what matters most to patients and to plan better research on heart failure treatments.
Hull, YorkshireAges 18 years+ - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44 - NCT07279649Recruiting
Studying a stent for blood vessel disease
This study is tracking how well a specific stent (GORE® VIABAHN® VBX) works over time in people who need treatment for narrowed or blocked blood vessels. It aims to see if the stent helps keep blood flowing long-term.
MunichAges 18 years+ - NCT07285655RecruitingPhase 3
Study of L606 for lung disease with high blood pressure in the lungs
This trial tests a new treatment called L606 for people who have both a type of lung disease (ILD) and high blood pressure in the lungs (PH). The goal is to see if it is safe and helps with exercise and breathing.
Phoenix, ArizonaAges 18–80 - NCT07279493RecruitingPhase 2
Testing KPCXM18 injection for acute ischemic stroke within 12 hours
This trial tests an investigational injection called KPCXM18 for people having an acute ischemic stroke. It is given within 12 hours of symptom onset, in addition to standard clot-dissolving treatment, to see if it improves recovery and safety.
Beijing, Beijing MunicipalityAges 18–80 - NCT07280013RecruitingPhase 1
Cemsidomide with elranatamab for multiple myeloma
This trial tests a new drug combination (cemsidomide and elranatamab) for people with multiple myeloma that has come back after previous treatments. The goal is to see if the combination is safe and works better than current options.
Gilbert, ArizonaAges 18 years+ - NCT07285005RecruitingPhase 3
Study of an oral drug for venous, lymphatic, and certain overgrowth syndromes
This trial tests whether the study drug KP-001 can help reduce symptoms like pain, fatigue, or bleeding caused by certain vascular malformations (abnormal blood vessel growths) that can't be surgically removed or haven't responded to other treatments. It's for people age 2 and older with specific conditions such as common venous malformations, lymphatic malformations, or KTS/CLOVES syndrome.
Charleston, South CarolinaAges 2 years+ - NCT07280247Recruiting
AlphaVac System for Treating Acute Pulmonary Embolism
This study tests a device that suctions blood clots from the lungs in people with a moderate-risk pulmonary embolism. The goal is to see if it is safe and effective at removing clots and improving blood flow.
Saint Cloud, MinnesotaAges 18 years+ - NCT07286890Recruiting
Beating Heart Bypass Surgery Study with Getinge Devices
This study follows patients who have a type of heart bypass surgery called 'beating heart' CABG, where a special Getinge device is used to keep the heart pumping during the operation. It helps doctors learn more about how well these devices work in real-world use.
Stockton, CaliforniaAges 22 years+ - NCT07284758RecruitingPhase 2
Cemsidomide and dexamethasone for relapsed/refractory multiple myeloma
This clinical trial tests a new combination of two medicines (cemsidomide and dexamethasone) for people with multiple myeloma that has come back or stopped responding after at least three prior treatments. The goal is to see if this new drug can help control the cancer when other options have stopped working.
Huntsville, AlabamaAges 18 years+ - NCT06884046Recruiting
Supporting parents of babies with heart conditions
This study offers support to parents whose baby is diagnosed with a heart condition before birth and will need surgery shortly after birth. The goal is to help parents manage stress during this difficult time.
Pessac, FranceAges birth–4 weeks
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.