Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05649904Recruiting
Study for adults needing brain fluid drainage after brain bleeding or infection
This study looks at patients age 18+ who need a procedure to drain brain fluid after certain brain bleeds (like intraventricular or subarachnoid bleeding, or chronic subdural bleeding) or after ventriculitis. It aims to better understand and improve care for people with these serious conditions.
Columbus, OhioAges 18 years+ - NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT05650411Recruiting
Test new drug-eluting stent with less blood thinner
This study compares a new type of “drug-eluting” stent (a tiny scaffold that slowly releases medicine) and a single blood-thinner plan versus the usual two-drug blood thinner plan after stent placement in the left main coronary artery. It aims to see if the simpler plan can work while keeping the stent safe.
Zurich, Canton of ZurichAges 18 years+ - NCT05650658Recruiting
Compare two heart pacing options in people with weak heart function
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
Gilbert, ArizonaAges 18 years+ - NCT05651724Recruiting
MASH screening study for people with diabetes or obesity
This study screens participants for MASH (a type of liver fat inflammation) using information about your health and risk factors. It may help you and your care team learn whether you could have MASH and need follow-up.
Brussels, Vlaams-brabantAges 18–75 - NCT05651945Recruiting
Cardiac rehab program for people after a stroke
This trial studies a supervised cardiac rehabilitation program for people after they have had a stroke. It may help improve heart-related fitness and recovery safety after stroke, especially for patients who need a tailored rehab approach.
Edison, New JerseyAges 18 years+ - NCT05652335RecruitingPhase 1
JNJ-79635322 for hard-to-treat myeloma or amyloidosis
This Phase 1 study tests how safe and how well JNJ-79635322 works in people with multiple myeloma that has come back or is resistant to treatment, or AL amyloidosis that has already been treated. It may help by targeting cancer cells and abnormal proteins driving these diseases.
Duarte, CaliforniaAges 18 years+ - NCT05653141Recruiting
Study for thinking problems after a first stroke
This trial looks at treatments or approaches to improve thinking and memory problems after a first stroke. You may be eligible if your stroke was in the front part of the brain, confirmed by MRI, and you enroll within 10 days.
BernAges 18 years+ - NCT05653440RecruitingPhase 2
Naming therapy training for chronic post-stroke aphasia
This Phase 2 trial studies a speech therapy approach that teaches people with aphasia how to name words, using different learning methods. You may be able to join if your language problem started after a stroke and has lasted more than 6 months.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05653466RecruitingPhase 2
Telehealth therapy schedule for stroke-related aphasia patients
This trial tests an approach that adjusts therapy scheduling for people with long-lasting (over 6 months) language problems after a stroke. It may help some patients by matching the therapy timing to what works best for them.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05654272Recruiting
Testing CIRC imaging technology for people with heart problems
This study is developing and testing CIRC technologies using heart imaging. You may be able to join if you’re an adult with cardiovascular (heart) disease and can safely have the MRI scans.
Cleveland, OhioAges 18 years+ - NCT05655910Recruiting
Nutrition support program for people with LVADs in the hospital
This trial tests whether an enhanced nutrition plan can improve care for adults who already have an LVAD (a heart pumping device). It’s designed for hospitalized patients and looks at who can safely eat by mouth while avoiding high-risk situations.
New York, New YorkAges 18 years+ - NCT05655897Recruiting
Clips for leaky mitral valve in high-surgery-risk heart patients
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
Suzhou, JiangsuAges 18 years+ - NCT05659160Recruiting
Triage approach for certain strokes from blocked large brain arteries
This trial studies a way to sort and treat people with a specific type of acute ischemic stroke (caused by a blockage in a large brain artery). It may help doctors choose the best next steps—either a procedure or medication—faster and more appropriately.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05660811RecruitingPhase 4
Antiplatelet medicines after left atrial closure in dialysis patients
This trial looks at the best blood-thinning (antiplatelet) plan after a left atrial appendage closure procedure in people with kidney failure on dialysis. It may help reduce stroke risk while also lowering medicine-related side effects.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT05660733Recruiting
Study of infections of the aorta and large arteries
This trial studies how to care for infections that involve the aorta or other large blood vessels. If you have signs and test results that fit this diagnosis, you may be invited to help researchers better understand the condition and treatments.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT05662293Recruiting
Study of heart muscle weakness caused by abnormal heart rhythms
This study looks at a condition where an abnormal heart rhythm can weaken the heart muscle (arrhythmia-induced cardiomyopathy). You may be asked questions, have heart tests reviewed, and help researchers better describe who is affected and how it develops.
BaselAges 18 years+ - NCT05663281Recruiting
Imaging treatment plan for blocked brain or neck arteries
This study uses special MRI “vessel wall” imaging to better understand blocked arteries in the brain or neck, confirmed on a scan. It aims to help analyze imaging findings to guide treatment decisions and reduce problems from artery blockage.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05663359Recruiting
Compare two laser treatments for varicose vein reflux
This trial tests whether a 1940 nm or a 1470 nm laser works better for treating varicose veins in the legs. It may help you find a more effective option to reduce vein problems like swelling, heaviness, and visible bulges.
ToulouseAges 18 years+ - NCT05664412Recruiting
Brain stimulation trial to improve thinking in 22q11.2 deletion
This trial tests a non-invasive brain stimulation approach to help improve executive function—skills like planning, attention, and self-control—in people with 22q11.2 deletion syndrome. If you qualify, you would be asked to participate and allow study procedures to see whether this treatment helps.
Geneva, Canton of GenevaAges 14–25 - NCT05664308Recruiting
Watch-based heart rhythm monitoring after heart surgery
This study tests whether a connected watch can help monitor an irregular heart rhythm (atrial fibrillation) after heart surgery. It looks at people who develop new atrial fibrillation after surgery and compares how well monitoring works over the next 12 months.
Nantes, Loire AtlantiqueAges 18 years+ - NCT05665608Recruiting
Prevent sudden death after a heart attack with a defibrillator
This trial studies whether implanting a defibrillator (ICD) soon after a heart attack can lower the risk of sudden cardiac death in people with weaker heart pumping and symptoms of heart failure. It compares strategies around defibrillator implantation, aiming to improve safety and outcomes.
FeldkirchAges 18 years+ - NCT05667519Recruiting
Ultrasound-guided pacemaker lead placement to prevent valve leak
This trial tests a way to place a pacemaker lead using a special ultrasound view through the esophagus (a transesophageal echocardiogram). The goal is to reduce the chance of developing a serious leak in the tricuspid valve caused by the pacemaker lead.
Munich, BavariaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.