Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06875466Recruiting
Can sauna bathing help your heart
This study looks at whether regular sauna bathing can improve health. If you qualify, you would use a sauna several times a week for a set period, and researchers will check your blood pressure and other heart risk factors.
TaurangaAges 18–70 - NCT06882954Recruiting
Managing Asymptomatic Carotid Stenosis
This trial studies the best way to treat people who have a high-grade blockage in their carotid artery but no symptoms. It focuses on blockages greater than 80% with signs of unstable plaque to prevent future strokes.
Roma, RMAges 18 years+ - NCT07284576Enrolling by invitationPhase 2
Low-dose PET scan for heart imaging
This trial tests a very low dose of a radioactive tracer (18F-flurpiridaz) for PET scans of the heart. It aims to see if using less radiation still produces clear images, which may be safer for patients who need repeated scans.
Englewood, New JerseyAges 18–120 - NCT07287345RecruitingPhase 4
Colchicine’s effect on inflammation after heart bypass surgery
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Lexington, KentuckyAges 18–99 - NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT07286227Recruiting
Checking heart function before removing support tubes in heart surgery
This study compares two methods—visual checks and a special ultrasound of the heart—to see which better predicts how well the heart will pump after bypass machine support is removed during elective heart surgery.
ErzurumAges 18–75 - NCT07281131Enrolling by invitation
Medication check before your doctor visit
This study tests if a pre-visit questionnaire helps older adults and their doctors talk about certain medications. You may be asked about taking a statin for heart health or stopping a high-risk medication.
Boston, MassachusettsAges 65 years+ - NCT07281859Recruiting
Heart monitor alert study for new ICD patients
This study tests a heart failure alert system called HeartInsight in people who recently received an ICD or CRT-D device. The goal is to see if the alerts help doctors manage care better. You may qualify if you got a new (not replacement) device less than a year ago.
Mercogliano, AvellinoAges 18 years+ - NCT07283224Recruiting
Using existing data to improve multiple myeloma care
This study uses already collected, de-identified data from past multiple myeloma trials to learn more about the disease. It does not involve any new treatments or procedures.
Bologna, BoAges 18 years+ - NCT07285915Recruiting
Stress and Cortisol in Cardiac Arrest
This study looks at how stress (specifically the hormone cortisol) affects people during a cardiac arrest. It may help doctors understand and improve care.
Pilsen, Czech RepublicAges 18–100 - NCT07285720Recruiting
Language Development in Williams Syndrome
This study looks at how children and adults with Williams syndrome learn language. Researchers want to understand how sounds and word patterns affect language skills in this condition.
AmiensAges 6 years+ - NCT07287059Recruiting
Wearable robot and virtual reality for hand recovery after stroke
This study tests if combining a wearable robotic glove with virtual reality exercises can help improve hand function in people who have had a stroke. It may be a good fit if you have some movement in your hand and arm but need more help.
Istanbul, BeykozAges 30–60 - NCT07285239RecruitingPhase 3
Comparing two drug combinations for newly diagnosed multiple myeloma
This trial compares two different combinations of medications for people with newly diagnosed multiple myeloma who are not planning to have a stem cell transplant. It looks at whether adding a targeted antibody drug is as effective as the standard approach.
La Crosse, WisconsinAges 18–79 - NCT07283289Recruiting
Obstructive sleep apnea in patients with PAD
This study looks at how common obstructive sleep apnea is in people with peripheral artery disease (PAD). Participants will have a sleep test as part of their regular care.
Toulon, VarAges 18 years+ - NCT07286435Recruiting
Vibration therapy after botox for stroke spasticity
This trial tests if adding whole-body vibration therapy to botulinum toxin A (Botox) injections can improve muscle stiffness, balance, and walking in stroke survivors. It may help reduce spasticity and make daily activities easier.
Bursa, BursaAges 18–75 - NCT07279870Recruiting
Comparing heart pacing methods for patients with heart block
This study compares two ways to pace the heart in people who have a slow or blocked heart rhythm. The goal is to find which method works better for patients with certain types of heart block.
BariAges 18 years+ - NCT07282938Recruiting
Robot hand and electrical stimulation for hand function after stroke
This test combines a soft robotic hand and electrical stimulation to help improve hand movement in people recovering from a stroke. It may benefit stroke survivors who have some ability to extend their fingers and are in the early months of recovery.
Lahore, Punjab ProvinceAges 45–65 - NCT07284446Recruiting
Depression, memory, and outcomes in heart failure patients
This study looks at how depression and memory problems affect recovery in people hospitalized with worsening chronic heart failure. It aims to find better ways to support patients during their hospital stay.
KaunasAges 18–85 - NCT07283159RecruitingPhase 2
Tenecteplase plus a second drug for stroke recovery
This study tests whether giving a second drug (urinary kallidinogenase) after the clot-busting drug tenecteplase can help people with moderate to severe ischemic strokes recover better. It is for patients who started treatment within 4.5 hours of symptoms.
ShenyangAges 18 years+ - NCT07283809Recruiting
Heart care study for patients with common heart problems
This study is collecting information about people with common heart conditions to help doctors learn how to offer better care. If you have had a heart attack, heart failure, or atrial fibrillation, your experience can help improve treatment for others.
Montevarchi, AREZZOAges 18 years+ - NCT07279259RecruitingPhase 2
Blood pressure management after stroke clot-dissolving treatment
This trial tests how managing high blood pressure during clot-dissolving treatment for acute ischemic stroke affects recovery. It is for patients who have high blood pressure at the start of treatment.
ShanghaiAges 18–80 - NCT07285187Recruiting
Vein congestion and confusion after heart surgery trial
This trial looks at how blood backing up in veins after heart surgery might relate to delirium (sudden confusion). It uses a special ultrasound to check vein blood flow and then watches for confusion afterward.
Yangzhou, JiangsuAges 18 years+ - NCT07282301Recruiting
Filter to catch debris during leg artery cleaning
This trial tests a special filter that catches debris during a procedure to clear blockages in the leg artery (the one behind the knee). It aims to reduce the risk of debris traveling to smaller blood vessels, which can cause complications. If you have a hardened leg artery and plan to have plaque removal before a stent or balloon, this study may be for you.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07286578Recruiting
Using heart CT scans to guide treatment for blocked arteries
This trial is testing whether a special heart CT scan (coronary CT angiography) can help doctors better understand and treat calcium buildup in your heart arteries. If you have a type of heart disease that might need a stent or other procedure, this study could help decide the best approach.
Boston, MassachusettsAges 18–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.