Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04924998Recruiting
Study for AL-CM treatment in adults at one hospital
This study is looking at a treatment approach for people diagnosed with AL-CM at a specific hospital. It may help researchers understand whether the treatment is safe and effective for patients like you.
Hangzhou, ZhejiangAges 18–80 - NCT04931550Recruiting
Pacemaker site study to see which placement is best
This study looks at whether placing a pacemaker in different locations affects how patients do afterward. If you recently had a pacemaker implanted and can follow study instructions, you may be able to help researchers compare outcomes.
Hangzhou, ZhejiangAges 18–100 - NCT04935021RecruitingPhase 4
Study of ATTR cardiac amyloidosis in patients and gene carriers
This study looks at ATTR cardiac amyloidosis (a condition caused by an inherited protein change) in people who have the disease or carry the gene. It may help researchers learn how ATTR affects the heart and how care can be improved.
Hangzhou, ZhejiangAges 18–80 - NCT02219984Recruiting
Survey of adults taking blood thinners in a patient registry
This study builds a registry by asking adults who take blood thinners (anticoagulants) about their experiences. It may help improve care by learning how these medicines are used in real life.
Bologna, BOAges 18 years+ - NCT05699629Recruiting
Study of people with coronary heart disease or chest pain
This trial follows people who have coronary heart disease or ongoing chest pain that needs a heart scan called coronary angiography. It also includes healthy volunteers for comparison, to help researchers understand risk factors and outcomes over time.
Jinan, ShandongAges 18 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT02910180Recruiting
Biobank study of genetic and metabolic data in brain blood vessel disease
This study collects genetic and other health information from people with brain blood vessel (cerebrovascular) problems. It aims to help researchers understand causes and patterns that could lead to better care in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05236153Recruiting
Study of heart valve procedure in repaired Tetralogy of Fallot
This study looks at how a transcatheter pulmonary valve replacement works in people with repaired Tetralogy of Fallot or double outlet right ventricle. The goal is to better understand the heart’s anatomy and how it may affect the valve procedure.
Boston, MassachusettsAges Any age - NCT05614193Recruiting
Deep imaging study for suspected stroke patients
This trial studies an advanced way to analyze CT or MRI scans for people who may have had a stroke or reduced blood flow to the brain. It aims to improve how scans are interpreted and shared for better care.
Beijing, Beijing MunicipalityAges 18–100 - NCT03820492Recruiting
Testing imaging tools to assess a narrowed left main artery
This trial compares different heart scans to decide how serious a narrowing is in the left main coronary artery. It may help doctors choose the safest and most accurate way to manage that blockage during a heart catheter procedure.
Clermont-FerrandAges 18 years+ - NCT05719545Recruiting
Study of people getting a heart procedure through the skin
This study follows people who have an acute heart problem and need a heart procedure done through the skin. It may help researchers better understand care for people in this urgent situation.
Jinan, ShandongAges 18–85 - NCT04657783Recruiting
French cohort study of people with type 1 diabetes
This study follows people with type 1 diabetes in France to better understand the condition over time. It may help researchers improve future care, especially for how type 1 diabetes starts and is managed from early diagnosis onward.
ParisAges 6–100 - NCT04029844Recruiting
Transcatheter valve replacement for older adults with severe aortic stenosis
This study tests a new “through-a-vein” heart valve procedure for people age 75+ with severe aortic valve narrowing that causes symptoms. It aims to see if the new valve can be safely implanted and improve outcomes in higher-surgery-risk patients.
LilleAges 75 years+ - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04628078Recruiting
Echocardiogram-guided heart procedure registry for atrial fibrillation
This study keeps a real-world record of people with atrial fibrillation who are planning a procedure to close off the heart’s left atrial appendage. Doctors use echocardiography (heart ultrasound) to guide the closure and track outcomes to improve care.
BernAges 18 years+ - NCT05740397Recruiting
Testing blood pressure targets during heart-lung bypass
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
VeronaAges 18–80 - NCT05718622Recruiting
EECP for people with stable first stroke and blocked artery
This study looks at whether EECP (a non-surgical therapy that helps blood flow) improves outcomes in people who recently had their first ischemic stroke and have a narrowed or blocked artery. It also aims to predict who may benefit most based on health data.
Xi'an, ShaanxiAges 18–80 - NCT02638389RecruitingPhase 3
Sirolimus for hard-to-treat vascular birthmarks
This Phase 3 study tests whether sirolimus helps control complex vascular anomalies that have not responded to standard treatments. It also checks safety by monitoring blood tests, organ function, and overall health during treatment.
Brussels, Brussels CapitalAges 3 months–70 years - NCT05709626RecruitingPhase 4
Testing prasugrel alone after stent placement for heart attack
This study checks whether taking prasugrel by itself, after you get a drug-eluting stent for a heart attack (STEMI), can work as well as the standard approach. It may help prevent blood clots in the stent, but it requires specific blood-thinner plans for 12 months.
Sayama, OsakaAges 18 years+ - NCT05320263Recruiting
Thrombectomy timing: aspiration tube vs stent for basilar stroke
This trial compares two ways to remove a blockage in the brain’s basilar artery: suction (aspiration) versus a retriever stent. It may help doctors learn which approach works better for restoring blood flow in acute stroke patients.
BordeauxAges 18 years+ - NCT05752383Recruiting
Study of how cardiogenic shock patients do in the ICU
This study looks at what happens to people with cardiogenic shock while they are in the intensive care unit (ICU), including how their heart and blood circulation change over time. It may help doctors better understand the course of illness in this specific type of shock and improve care.
AmiensAges 18 years+ - NCT05749250Recruiting
Ultrasound treatment for severe leg artery disease ulcers
This trial studies a specific ultrasound-based treatment aimed at improving healing of severe circulation-related ulcers in the legs. It may help if you have poor blood flow and a wound that hasn’t improved despite usual care.
Charlottesville, VirginiaAges 18 years+ - NCT05754138Recruiting
Testing sports safety with a subcutaneous defibrillator
This study looks at whether it is safe to play sports if you have a specific type of implanted defibrillator under the skin. It will track your device performance and exercise habits, using home monitoring, to understand any risks from sports.
Tel AvivAges 10–60
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.