Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT07106970Recruiting
Comparing two ablation approaches for persistent atrial fibrillation
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
BeijingAges 18–80 - NCT07251894Enrolling by invitation
Meals after heart failure hospitalization
This study provides medically tailored meals to people recently hospitalized with heart failure to see if they help recovery. It is testing whether having healthy meals delivered can improve how patients feel and reduce the chance of being readmitted to the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07166133Recruiting
GORE TAG Thoracic Branch Endoprosthesis for Zone 0/1 Study
This study is checking how well the GORE TAG Thoracic Branch Endoprosthesis works for people who need a stent graft in a specific part of the aorta (Zone 0 or 1). It may help if you have an aneurysm or other condition requiring treatment in that area.
Scottsdale, ArizonaAges 18 years+ - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+ - NCT07510438Recruiting
Pulse IVL treatment for hardened arteries in the heart
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries, making them easier to open. It may help people with coronary artery disease who have not had prior stents or recent heart attacks.
Sydney, New South WalesAges 18 years+ - NCT05850234RecruitingPhase 1/Phase 2
Study drug for hard-to-treat multiple myeloma after prior treatments
This Phase 1/2 study tests AZD0120 in people with multiple myeloma that has come back or is not responding to treatment. It may help by targeting the myeloma cells after you’ve already tried several standard therapies.
Birmingham, AlabamaAges 18 years+ - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Birmingham, AlabamaAges 18–100 - NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT07761728Enrolling by invitation
Comparing two heart PET scan tracers
This study compares two types of radioactive tracers used during heart PET scans to see if one is better at detecting blocked arteries. Participation involves receiving one of the tracers during your routine scan and may help improve heart disease diagnosis.
Los Angeles, CaliforniaAges 18 years+ - NCT07764978RecruitingPhase 3
New drug combo for multiple myeloma without stem cell transplant
This trial tests a new drug called AZD0120 added to standard treatments for people newly diagnosed with multiple myeloma who are not eligible for a stem cell transplant. It aims to see if the combination can better control the disease and improve outcomes.
Gilbert, ArizonaAges 18 years+ - NCT06895590Recruiting
Testing a new water-based blood pressure cuff
This trial tests a new, very accurate blood pressure cuff that uses water to get a better reading. It is for adults who already need a standard blood pressure cuff and an arterial line as part of their hospital care.
Boston, MassachusettsAges 18 years+ - NCT06865690Enrolling by invitation
CPR teaching methods for home nurses in Qatar
This study tests two different ways of teaching CPR to private home nurses in Qatar. The goal is to see which method helps you learn and remember CPR skills better, so you can feel more confident in an emergency.
DohaAges Up to 60 years - NCT06857058Recruiting
Drug-eluting stent for brain artery narrowing
This trial tests a drug-coated stent to treat severe narrowing in brain arteries. It may help reduce the risk of stroke in people with hardened arteries in the brain.
ZhengzhouAges 18–80 - NCT06812130Recruiting
Surviving the pediatric intensive care unit
This study looks at how children and their healthy siblings cope after a stay in the pediatric intensive care unit (PICU). It may help doctors and families better understand what support is needed during recovery.
Singapore, SingaporeAges 4 weeks–16 years - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT06421181Recruiting
Effects of Anesthesia on Heart and Blood Pressure
This study looks at how different anesthesia medicines affect your heart and blood pressure during open abdominal surgery. It may help doctors choose safer anesthesia for you.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT06259617Recruiting
Heart health in young athletes over 3 years
This study follows young athletes over three years to see how their hearts adapt to regular training. Researchers will use yearly checkups to learn more about heart health in active kids and teens.
München, BavariaAges 7–18 - NCT05931406Recruiting
Study to reduce sitting time at work for dispatch workers
This study tests how changing work movement—using tools like a sit-stand desk and a stationary bike—may improve health for emergency medical dispatchers and similar workers. It involves people who can give consent and are able to use the equipment at work.
Clermont-FerrandAges 18 years+ - NCT05743673Recruiting
SHAPE test to assess pre-surgery heart and lung risk
This trial studies a quick physical test (called the SHAPE test) given before surgery to help predict your risk of complications. It may help doctors choose safer care and monitoring based on your results.
New Haven, ConnecticutAges 60 years+ - NCT05482386Recruiting
Blood and health traits study in older people on statins
This study looks at blood markers (“biomarkers”) to better understand health risk in older adults who have multiple long-term illnesses and are taking statin medicines. It may help researchers predict outcomes and improve care for people with complex health needs.
BernAges 70 years+ - NCT05346094Recruiting
MRI measurements of normal heart values
This study uses heart MRI scans to create “normal” heart measurement ranges for people who don’t have heart disease. This can help doctors better spot abnormal heart changes in the future.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT05176769Recruiting
AI system to review hospital heart records in Greece
This trial uses a computer program to automatically study heart-care information stored in hospital computer records. It may help hospitals find insights faster from routine medical documentation.
AlexandroupoliAges 18 years+ - NCT03855722Recruiting
Remote heart protection before organ transplant
This study tests whether a simple treatment performed on the donor before organ removal can help transplanted organs work better. It may help patients receiving organs from eligible brain-dead donors at a specific hospital.
HelsinkiAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.