Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04349358Recruiting
PET/CT scan test to find bone lesions in new myeloma
This trial compares two types of PET/CT scans to see which one better finds lesions (areas of disease) in people with newly diagnosed multiple myeloma. If you qualify, you may help doctors choose the most useful scan to guide care.
BesançonAges 18–75 - NCT06090838Recruiting
Balloon angioplasty for blood clots in the lungs after pulmonary embolism
This trial tests whether balloon angioplasty can improve breathing and exercise ability in people who still have symptoms and blood flow problems 3 months or more after a pulmonary embolism. It is for those who have completed a pulmonary rehabilitation program.
Amsterdam, North HollandAges 18–80 - NCT06088927Recruiting
Long-term results of conduction system pacing
This study looks at how well a special type of pacemaker (conduction system pacing) works over time. If you've already had this procedure, joining could help doctors learn how to improve future care for people like you.
CaenAges 18 years+ - NCT06089031Recruiting
Belgian registry for coronary function testing
This study collects information from people having tests to check how well the blood vessels in the heart work. It helps doctors learn more about these tests and improve care for future patients.
Deurne, AntwerpAges 18 years+ - NCT05176132Recruiting
Obesity screening to find hidden weight-related health issues
This study screens adults of different body sizes to find “unrecognized” weight-related health problems. It may help doctors spot issues earlier and understand how common they are across weight groups.
EsbjergAges 18–60 - NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age - NCT06095466Recruiting
Heart check with ultrasound in severe liver disease
This study tests if a simple bedside heart ultrasound (echocardiogram) and blood tests can spot early heart problems in people with severe liver disease (cirrhosis) who are in the intensive care unit. It may help doctors better understand and manage heart complications in cirrhosis.
Sector-12, ChandigarhAges 18–65 - NCT06085612Recruiting
How carotid artery blockage affects blood flow in the retina
This trial examines how a narrowing of the main neck artery (carotid stenosis) impacts blood flow in the retina using a special eye test called automated retinal oximetry. The goal is to better understand how this blockage affects eye health.
OlomoucAges 18 years+ - NCT05573802RecruitingPhase 1/Phase 2
Belantamab and other medicines for new multiple myeloma
This early-phase study tests how safe and effective belantamab mafodotin is when combined with lenalidomide and dexamethasone, plus a medicine called nirogacestat, in people with newly diagnosed multiple myeloma who cannot have stem cell transplant. It may help shrink the cancer and improve outcomes, while doctors track side effects.
AthensAges 18 years+ - NCT06026436Recruiting
Predicting clot and bleeding risk in kidney disease patients after a heart attack
This trial tests whether a blood test looking at platelets and tiny cell particles can help predict future blood clots or bleeding in people who have both chronic kidney disease and a recent heart attack. The goal is to improve treatment safety.
MarseilleAges 18–90 - NCT03916302Recruiting
Pulmonary embolism registry study in Warsaw
This study keeps a registry (record) of people with a confirmed pulmonary embolism. Your information helps doctors better understand the condition and improve care.
WarsawAges 18 years+ - NCT06104033Recruiting
Drug-coated balloon for patients with heart artery disease in multiple vessels
This trial tests whether a drug-coated balloon is a good treatment option for people who have blockages in two or more heart arteries. It aims to see if this approach can safely open blocked arteries without a permanent stent.
SeoulAges 19–100 - NCT06104007Recruiting
Genoss balloon for narrowed heart stents
This study follows patients who have already received a special drug-coated balloon (Genoss® DCB) to treat a re-narrowed heart stent. It aims to see how safe and effective the balloon is in the long term.
SeoulAges 19 years+ - NCT06105242Recruiting
Sex differences in CTEPH heart function and recovery
This study looks at how CTEPH (a type of high blood pressure in the lungs caused by blood clots) affects heart function differently in men and women. It uses heart ultrasounds and pressure measurements to see if recovery after surgery differs by sex.
Murray, UtahAges 18 years+ - NCT04923191Recruiting
Test heart-procedure guidance from scans versus usual care
This study compares two ways of guiding a heart stent procedure: using information from a special angiography scan versus using standard practice. It may help your care team choose the best treatment to improve heart outcomes after stenting.
AalstAges 18 years+ - NCT06132711RecruitingPhase 1/Phase 2
CAR-T therapy for relapsed multiple myeloma
This trial tests a new kind of CAR-T cell therapy (called APRIL-BAFF-Bicephali CAR-T) for people with multiple myeloma that has come back or not responded to treatment. It aims to see if this therapy is safe and can help when other treatments have stopped working.
Xuzhou, JiangsuAges 18–70 - NCT06024759Recruiting
Finding risk factors in left ventricular non-compaction
This study looks at people with left ventricular non-compaction (a condition where the heart muscle is spongy) to find what factors might predict their health risks. By joining, you'll help doctors better understand and care for others with this condition.
London, OntarioAges 18 years+ - NCT06066450Recruiting
OSFIT Stent for Coronary Artery Blockage
This trial tests a special stent (OSFIT) in people with a blockage near the start of a coronary artery. The goal is to see if the stent works well for this specific location.
SuwonAges 19 years+ - NCT03110822RecruitingPhase 1
Ruxolitinib, steroids, and lenalidomide for hard-to-treat myeloma
This Phase 1 trial tests a combination of ruxolitinib plus steroids and lenalidomide in people with relapsed or refractory multiple myeloma. It’s designed for patients who have had at least two prior treatment options and whose myeloma is getting worse or not responding.
Alhambra, CaliforniaAges 18 years+ - NCT04617717Recruiting
Personalized treatment for abnormal heartbeats needing ablation
This trial studies a customized treatment plan for people who have premature ventricular beats (PVCs) and have been referred for a procedure called PVC ablation. It may help doctors choose the best approach for stopping these extra heartbeats.
OsloAges 18–90 - NCT06115096Recruiting
Heart pump blood flow study
This study looks at how blood flows inside your heart while you have a HeartMate 3 heart pump. It aims to understand your heart’s pumping function and may help doctors improve care for people with heart pumps.
Linköping, Östergötland CountyAges 18 years+ - NCT05021614Recruiting
Valveclip repair study for leaking mitral valve in older adults
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
SichuanAges 60 years+ - NCT05494034Recruiting
Monitoring heart rhythms after stroke to guide care
This study uses a small implantable heart monitor to track heart rhythm in people after an acute ischemic stroke or TIA. It aims to learn how often hidden heart rhythm problems show up, which could help doctors choose better stroke prevention treatments.
AthensAges 40–100 - NCT04814212Recruiting
Testing a drug-coated balloon for people with bleeding risk
This trial looks at whether a “drug-coated balloon” used during a heart procedure (PCI) is safer or better for people who are at higher risk of bleeding while on blood thinners. It may help reduce complications around the time of the procedure in people like you.
Jyväskylä, Central FinlandAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.