Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT07343674Recruiting
Studying a new heart valve replacement system for aortic stenosis
This trial is testing a new heart valve system (Medtronic Evolut FX+) for people with severe aortic stenosis—a condition where the heart's main valve is narrowed. The study aims to see how well the valve works and improve your care journey.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT07343895Recruiting
Atrial fibrillation screening in people with high NT-proBNP
This study is checking people over 40 who have a higher-than-average heart stress marker (NT-proBNP) to see if they have undiagnosed atrial fibrillation. You'll use a smartphone to track your heart rhythm at home.
TromsøAges 40 years+ - NCT07344012Recruiting
Parenting hopes in women with Turner syndrome
This study looks at women with Turner syndrome who wanted to become parents. It aims to understand what support they received and what happened with their parenting plans.
StrasbourgAges 18–40 - NCT07344480Recruiting
Study on heart disease in children with RASopathy
This study looks at medical records of children with a genetic condition called RASopathy who developed thickened heart muscle and needed hospital care for heart failure in their first six months of life. The goal is to understand how the heart condition progresses over time.
MünchenAges Any age - NCT07344610Recruiting
Short-term high-dose statin therapy after stroke
This trial tests whether starting a high dose of a statin (a cholesterol-lowering medicine) soon after a stroke can improve your cholesterol levels. It is for people who have had a stroke or have significant narrowing of arteries in the brain or neck.
Shenyang, LiaoningAges 18 years+ - NCT07344961Recruiting
Micra AV2 study: tracking heart rhythm and AFib
This study looks at how well the Micra AV2 pacemaker tracks your heart’s natural rhythm and detects brief episodes of atrial fibrillation (a fast, irregular heartbeat). It is for people who already have or will get this pacemaker and have had AFib that comes and goes.
New Hyde Park, New YorkAges 18 years+ - NCT07345325RecruitingPhase 3
Comparing antibiotic treatments for heart valve infections
This trial tests whether a treatment without rifampin works as well as one with rifampin for a type of heart valve infection caused by staph bacteria. It aims to find a simpler and safer option for patients with an infected artificial heart valve.
Aix-les-BainsAges 18 years+ - NCT07345533Recruiting
Heart Failure Monitoring with a Chest Sensor
This study tests a small chest sensor that tracks your heart activity while you're in the hospital. It may help doctors better manage heart failure and prevent future crises.
CaenAges 18–90 - NCT07345559Recruiting
Personalized blood pressure targets for cardiogenic shock
This trial tests whether setting a personalized blood pressure goal for each person in cardiogenic shock improves recovery compared to standard care. It may help if you have severe shock and can be enrolled within the first 24 hours.
AmiensAges 18 years+ - NCT07465627Recruiting
Vessel recoil study for below-knee artery disease
This study tests a new device called the Spur to open blocked arteries below the knee in people with severe leg pain or minor wounds. It is specifically for people who also have diabetes or are on dialysis.
GrazAges 18 years+ - NCT06965621RecruitingPhase 2
Heart Nerve Imaging in Heart Failure with ICD
This study uses a special imaging agent (18F-mFBG) to take pictures of the nerves in your heart. It aims to better understand heart function in people with heart failure and an ICD.
Houston, TexasAges 18 years+ - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT04916327Recruiting
Exercise program study for mental health and blood vessel health
This study tests whether an exercise training program can improve how well your blood vessels work in people with certain mental health conditions. You may join as someone with PTSD, someone with generalized anxiety, or as a healthy control group.
Richmond, VirginiaAges 18–35 - NCT05946564RecruitingPhase 3
Pioglitazone to protect kidney function in ANCA vasculitis
This Phase 3 trial tests whether pioglitazone can help protect kidney function in people with newly diagnosed or relapsing ANCA-associated vasculitis that is actively affecting the kidneys. It aims to improve “renal tolerance,” meaning your kidneys may be better able to tolerate the disease and treatment.
AmiensAges 18–80 - NCT04800276Recruiting
Exercise program for leg artery disease
This trial tests a supervised exercise program for people with leg pain when walking caused by narrowed leg arteries. The goal is to see if exercise can improve walking ability and quality of life.
Le MansAges 18 years+ - NCT06781034Recruiting
MRI appearance of brain bleeds in different small vessel diseases
This study looks at how different types of small blood vessel disease in the brain affect the appearance of a recent brain bleed on MRI. It may help doctors better understand and manage these bleeds.
Nîmes, GardAges 18 years+ - NCT07678697Recruiting
Laser and injection treatment for spider and reticular veins
This trial compares two types of laser treatments combined with injection therapy for small leg veins (spider veins and reticular veins). It aims to find which approach works better for cosmetic improvement.
CairoAges 18–60 - NCT07292272Recruiting
Slowing Aging in Blood Cancer Survivors
This study tests a program to help people who have survived a blood cancer stay healthier as they age. It involves exercise and check-ups to see if we can slow down some effects of aging.
Omaha, NebraskaAges 50 years+ - NCT06322732Recruiting
Better care for newborns with severe asphyxia at birth
This study looks at how routine hospital care for full-term or near-term newborns with severe oxygen deprivation at birth can be improved. It aims to find where care can be optimized to reduce complications.
Paris, Île-de-France RegionAges Up to 1 month - NCT05136131Recruiting
Quality-of-life support after cardioversion for persistent AF
This study looks at how a heart rhythm procedure (cardioversion) affects quality of life in people with persistent atrial fibrillation (AF). It may help you understand whether a specific approach can improve day-to-day symptoms and well-being after treatment.
Newmarket, OntarioAges 18 years+ - NCT06299514Recruiting
Pacemaker and ablation for heart failure with atrial fibrillation
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Victoria, British ColumbiaAges 18 years+ - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT06841198Recruiting
Heart and blood vessel health after spinal cord injury
This study looks at how the heart and blood vessels change in the first year after a spinal cord injury. It also tests if electrical stimulation can help improve low blood pressure, which is common after injury.
West Orange, New JerseyAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.