Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT02699957Recruiting
Left Atrial Appendage Closure Registry Study
This study tracks patients who have a minimally invasive procedure to close off a small pouch in the heart called the left atrial appendage. The procedure aims to reduce stroke risk, and this registry collects information about how patients do after the procedure.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02696135Recruiting
Study of Chinese people with hypertrophic cardiomyopathy
This study looks at people with hypertrophic cardiomyopathy (HCM), a heart condition that causes part of the heart muscle to thicken for no clear reason. It will compare how HCM is identified and studied, which may help doctors better understand and manage the condition in Chinese patients.
Beijing, Beijing MunicipalityAges Any age - NCT02323581Recruiting
Stent procedure for large aortic aneurysms with custom grafts
This trial studies a less invasive “through-the-blood-vessel” stent graft procedure for large aneurysms in the main aorta or the aortic arch. It may help reduce the risk of aneurysm rupture while avoiding open surgery for people at higher surgical risk.
New York, New YorkAges 18 years+ - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+ - NCT02347111RecruitingPhase 4
Genetic study to guide antiarrhythmic drugs for atrial fibrillation
This study looks at how a person’s genetics may affect how well and safely antiarrhythmic medicines work for atrial fibrillation (AF). If you join, you may get medicine options like flecainide or sotalol, and researchers compare outcomes to genetic information.
Chicago, IllinoisAges 18–100 - NCT02453919Recruiting
Study of heart complications in people living with HIV
This study looks back at people with HIV to understand how often and why heart problems happen. It may help doctors better track heart risk and complications over time.
ParisAges 18 years+ - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT02387255Recruiting
MRI test for abdominal aortic aneurysms using a pressure-sound scan
This trial uses a special MRI scan called magnetic resonance elastography to study abdominal aortic aneurysms. It may help doctors better measure and understand how the aneurysm tissue behaves.
Columbus, OhioAges 20 years+ - NCT02558699Recruiting
Virtual mapping guided catheter ablation for atrial fibrillation
This trial tests whether a “virtual” computer map created from your heart scans can help doctors do catheter ablation to treat atrial fibrillation (AF). It aims to improve the procedure for people whose AF symptoms were not controlled well with anti-arrhythmia medicines.
SeoulAges 19–80 - NCT02691689Recruiting
Genetics study in families with congenital heart defects and PAH
This study looks at genes that may contribute to pulmonary arterial hypertension (PAH) in people born with certain heart “shunts” (holes between heart chambers). If you have (or your family has) ASD or VSD and PAH confirmed by a heart pressure test, you may be invited to share genetic and health information to help researchers understand risk and better target future care.
LeuvenAges 18 years+ - NCT02472028RecruitingPhase 4
Lower blood pressure to protect the brain in older adults
This study tests whether better blood pressure control can slow changes seen on brain scans in older people. It focuses on people with high blood pressure and “wear-and-tear” type brain lesions on MRI.
Bordeaux, Pellegrin Hospital GroupAges 60–88 - NCT02708134Recruiting
Study of CPR quality in children and young adults
This trial looks at how well CPR (chest compressions) is done during an emergency resuscitation in children and young adults. The goal is to understand what helps improve care during life-saving resuscitation.
Los Angeles, CaliforniaAges birth–18 years - NCT02541435Recruiting
Breast cancer radiotherapy side effects study
This study looks at heart and blood-vessel side effects after modern radiation treatment for breast cancer, both soon after and years later. It may help doctors understand who is at risk and how to monitor heart health over time.
ÅlesundAges 30–70 - NCT02638701RecruitingPhase 1/Phase 2
Infliximab for hard-to-treat brain blood vessel aneurysms
This Phase 1/2 trial tests infliximab, a medicine that calms inflammation, for dolichoectactic aneurysms in the vertebral/basilar brain blood vessels that usually cannot be treated with standard surgery or procedures. The goal is to see if it can improve safety and how the aneurysm behaves over time.
San Francisco, CaliforniaAges 18 years+ - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT02641145Recruiting
PET/MRI scans in light-chain amyloid heart disease
This study uses special PET and heart MRI scans to better understand light-chain amyloidosis affecting the heart. The scans may help researchers see how the disease behaves in different patient groups and treatment states.
Boston, MassachusettsAges 18–99 - NCT02648009RecruitingPhase 1
Heart metabolic MRI using a special injected tracer
This Phase 1 study tests whether a specialized heart MRI injection can show how the heart uses energy. It may help researchers better understand heart muscle thickening and related conditions, and identify heart-related changes early.
Toronto, OntarioAges 19–75 - NCT02793999Recruiting
Near-infrared monitoring to guide cooling in newborns
This study tests a special, non-invasive sensor (near-infrared light) to help doctors choose the best cooling treatment for some newborns after brain injury. It may improve how well cooling works and how safely it’s managed in the first week of life.
Boston, MassachusettsAges Up to 2 years - NCT02693509Recruiting
Hospitalized heart failure patients can join a heart study registry
This study collects information from people who are hospitalized for congestive heart failure. It helps researchers understand how heart failure is treated in real-world care and may improve future guidelines.
Dallas, TexasAges 18–125 - NCT02693223Recruiting
Get With the Guidelines Stroke Registry for people with recent stroke
This study collects health information from people who were recently treated for certain types of stroke or “TIA” (a warning stroke). It helps doctors understand care and improve future treatment, and you may be included if you were treated in the hospital for one of these conditions.
Dallas, TexasAges 18–125 - NCT02693548Recruiting
Study of families with familial high cholesterol
This is a study that follows people with a genetic form of very high cholesterol (familial hypercholesterolemia) and their close relatives. It aims to better understand this condition in real families and how it affects health over time.
MadridAges 15 years+ - NCT02741349Recruiting
Checking stroke and bleeding risks in atrial fibrillation
This study looks at how to better predict both stroke risk and bleeding risk in people with atrial fibrillation. It may help doctors choose safer blood-thinner treatment and follow-up plans.
ParisAges 18 years+ - NCT02748226Recruiting
Study of artery procedures for leg artery disease outcomes
This study looks at results of a minimally invasive procedure done inside blood vessels (endovascular therapy) for people with painful or worsening leg artery disease. It uses both past (retrospective) and future (prospective) patient information to better understand outcomes.
SeoulAges 20 years+ - NCT02778724Recruiting
Heart catheterization registry for adults who had angioplasty
This study is a national registry that collects information from adults who had a heart catheter test (coronary angiogram) or a procedure to open blocked heart arteries (angioplasty). It helps doctors better understand how these procedures are used and what outcomes patients experience.
Le Coudray, Eure Et LoireAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.