Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT02804074Recruiting
Treat “hidden” high blood pressure using 24-hour monitoring
This study looks at better treatment for people whose blood pressure looks okay in the clinic, but stays high during daily life or at night. It uses 24-hour blood pressure monitoring (a test that checks readings throughout the day) to guide care and see if it helps control “masked uncontrolled” hypertension.
MilanAges 35–80 - NCT02850588Recruiting
Track outcomes after carotid stent or surgery
This study follows people who need a procedure to treat narrowed carotid arteries, comparing results after either surgery (CEA) or a less invasive procedure (TCAR). It mainly looks at patient safety and outcomes, which can help improve future care.
Chicago, IllinoisAges 18 years+ - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT02884271Recruiting
Study CPR during surgery when the heart stops
This trial looks at cardiopulmonary resuscitation (CPR) provided right in the operating room when a patient’s heart stops. It may help improve how emergency care is delivered during surgery.
IzmirAges Any age - NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Phoenix, ArizonaAges 18 years+ - NCT03004326Recruiting
Biopsy study to test skin inflammation gene signals
This study uses a skin biopsy to look at “gene signals” (transcriptomics) in patients with active vasculitis that shows up on the skin. It may help researchers understand what is happening in your disease and how different types of vasculitis differ.
Los Angeles, CaliforniaAges 5 years+ - NCT03385122Recruiting
Study of environment and heart health in Corinthia
This study looks at how people’s surroundings in the Corinthia region may relate to heart (cardiovascular) health. It will include adults from the region who can consent to participate.
Athens, AtticaAges 40 years+ - NCT03313687Recruiting
Safety and outcomes of modern treatments for shock
This study looks at how safe and effective current treatments are for people who have cardiogenic shock, a serious condition when the heart cannot pump enough blood. It mainly aims to understand outcomes from treatment in a hospital setting, which may help improve care for future patients.
HamburgAges 18 years+ - NCT03383419RecruitingPhase 2
Hepatitis C–safe antiviral plan for heart transplant recipients
This Phase 2 trial tests giving newer hepatitis C medicines in a careful way to people getting a heart transplant who currently do not have hepatitis C in their blood. The goal is to lower hepatitis C infection risk from donated organs while keeping transplant outcomes safe.
Los Angeles, CaliforniaAges 18–90 - NCT03218137RecruitingPhase 4
Adenosine test during heart procedure for frequent PVCs
This trial studies how a drug called adenosine helps doctors understand why premature ventricular contractions (PVCs) are happening. The goal is to guide treatment, including catheter ablation, for people with PVCs.
New York, New YorkAges 18–70 - NCT03065231Recruiting
Lumbar vs external brain fluid drain to prevent blood vessel spasm
This study compares two types of drainage tubes used in people with a serious bleeding around the brain, aiming to prevent a complication called blood vessel spasm. If you qualify, it may help doctors learn which drainage method works best for safer recovery.
San Diego, CaliforniaAges 18–110 - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT03209583Recruiting
Test of fast-pacing therapy for congenital heart rhythm issues
This trial studies whether a device-based fast pacing therapy (called ATP) can better treat certain rapid heart rhythm problems in people born with a heart condition. It may help prevent or reduce episodes of atrial (upper-chamber) arrhythmias that occur despite having a pacing/defibrillator device.
Los Angeles, CaliforniaAges Any age - NCT03149705Recruiting
Study group of adults with ischemic stroke
This study looks at adults who have had an ischemic stroke confirmed on MRI and a blockage in a major brain artery. Researchers want to understand stroke care in people who can receive standard clot-busting treatment (thrombolysis) and/or clot removal (thrombectomy).
BronAges 18 years+ - NCT03243175RecruitingPhase 3
Avoiding blood thinners after brain bleeding in atrial fibrillation
This Phase 3 trial studies whether it’s safer to avoid long-term blood thinners after a spontaneous brain bleed in people with atrial fibrillation (an irregular heart rhythm). It compares different prevention strategies to lower the risk of stroke or other blood-vessel problems without causing new, serious bleeding.
LilleAges 18 years+ - NCT03314974RecruitingPhase 2
Stem cell transplant study for blood cancers
This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT02923440Recruiting
Donate DNA and help build a congenital heart study database
This study creates a DNA bank and a French database for babies and children with certain types of congenital heart defects, to better understand genetic causes. You’ll be asked to have a blood test and share consent, even though care can continue as usual at the study hospital.
MarseilleAges Any age - NCT02925819Recruiting
Study for severe mitral valve disease when surgery isn’t an option
This trial focuses on people with severe mitral valve narrowing or leaking who still have symptoms even after the best usual medications. It may help find better care and measure health outcomes when surgery is judged too risky or not suitable.
LyonAges 18 years+ - NCT03291392Recruiting
CUHK stroke biobank for blood, fluid, and tissue samples
This study builds a research bank using samples from people with stroke, their family members, and some people without narrowing in their blood vessels. Your samples help researchers study stroke and related brain and vessel changes.
Hong KongAges 18 years+ - NCT03375619Recruiting
Long-term follow-up after CAR-T treatment
This study checks in with people who already received CAR-T therapy to learn how they’re doing over time. It may help doctors understand the long-term benefits and side effects of CAR-T for future patients.
Milwaukee, WisconsinAges 18–80 - NCT03197350Recruiting
Study of heart failure with preserved pumping function
This study looks at people who have heart failure symptoms but whose heart pumping strength is not reduced. Researchers aim to better understand this type of heart failure and compare it with people who have no history of heart disease or heart failure.
BrusselsAges 18–99 - NCT03268135Recruiting
Study gene activity in people with heart failure or aortic stenosis
This trial looks at patterns in your blood or heart-related “gene activity” (transcriptome) after heart procedures. It may help doctors understand why some people with heart failure or aortic valve narrowing (stenosis) do better than others.
San Donato Milanese, MilanAges 40–75 - NCT03204357Recruiting
Using your own blood after heart-lung machine surgery
This trial studies giving a “fresh” blood transfusion from your own blood after heart surgery that uses a heart-lung machine. It may help patients avoid needing donated blood, but it only works for people who meet specific safety and timing requirements.
Aurora, ColoradoAges 18–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.