Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT02201589Recruiting
Endovascular repair for certain ascending aorta problems
This trial studies whether a minimally invasive (endovascular) procedure can safely treat specific serious problems of the ascending aorta. It may help people who are too high-risk for standard open-heart surgery, but only if their anatomy fits and certain risks are ruled out.
Long Beach, CaliforniaAges 18 years+ - NCT02910180Recruiting
Biobank study of genetic and metabolic data in brain blood vessel disease
This study collects genetic and other health information from people with brain blood vessel (cerebrovascular) problems. It aims to help researchers understand causes and patterns that could lead to better care in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT02824822Recruiting
Genetic test study for heart rhythm risk in people with seizures
This study checks whether genetic markers are linked to heart rhythm problems in people with epilepsy or seizure-related events, and in some close relatives. It may help doctors better spot who is at risk for dangerous heart rhythm issues.
Rochester, MinnesotaAges 18–50 - NCT02638389RecruitingPhase 3
Sirolimus for hard-to-treat vascular birthmarks
This Phase 3 study tests whether sirolimus helps control complex vascular anomalies that have not responded to standard treatments. It also checks safety by monitoring blood tests, organ function, and overall health during treatment.
Brussels, Brussels CapitalAges 3 months–70 years - NCT02445534Recruiting
Registry for cell therapy in non-ischemic dilated heart muscle disease
This is a research registry that follows people with non-ischemic dilated cardiomyopathy (a weakened heart muscle) who are already on the right medications. It helps doctors better understand how cell-based therapy and related care affect heart function over time.
LjubljanaAges 18–65 - NCT02770066Recruiting
Registry study of PTRA in difficult-to-control blood pressure
This study keeps track of people with renovascular hypertension (high blood pressure likely linked to blocked kidney arteries) who may receive a procedure called PTRA. It aims to understand who benefits and how kidney and heart outcomes change over time.
AalborgAges Any age - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT02781922RecruitingPhase 3
Stem cell infusion for single-ventricle heart failure during surgery
This trial tests whether an infusion of heart stem/progenitor cells can improve outcomes for children with a single working heart chamber (single ventricle) who are scheduled for the next surgical stage (Glenn or Fontan). It may help the heart function after surgery, but participation depends on several heart, lung, brain, and overall health safety criteria.
KanagawaAges birth–6 years - NCT02896348Recruiting
Home therapy training for hand function after stroke
This trial tests a physio-and-neuro “platform” to help retrain hand movement at home in people who are at least 6 months out from a stroke. It may help improve hand function and confidence doing daily tasks using an at-home retraining program.
Boston, MassachusettsAges 21–80 - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT02608996RecruitingPhase 1/Phase 2
Nesiritide test for hard-to-control blood pressure
This Phase 1/2 study tests nesiritide, a medicine that affects blood vessels and heart strain, to see if it can improve blood pressure control in people with hypertension. It’s mainly for people whose blood pressure stays high even during the day despite medication.
OsloAges 18–79 - NCT02219984Recruiting
Survey of adults taking blood thinners in a patient registry
This study builds a registry by asking adults who take blood thinners (anticoagulants) about their experiences. It may help improve care by learning how these medicines are used in real life.
Bologna, BOAges 18 years+ - NCT02245763Recruiting
Mitral valve procedure registry for patients who can take blood thinners
This is a study that collects medical information about people having a mitral valve procedure, to better understand outcomes. It may help because it improves how doctors choose and manage care for mitral valve problems.
Washington D.C., District of ColumbiaAges 1 year+ - NCT02240862Recruiting
Carotid artery disease registry for symptom and risk groups
This is a registry that enrolls adults with narrowed carotid arteries (with symptoms or no symptoms). It collects health and treatment information to better understand which patients benefit from procedures and when.
Baltimore, MarylandAges 18–80 - NCT02792075Recruiting
Study heart artery narrowing seen on special imaging
This study follows people who already have a heart artery imaging test to understand what the imaging means for future heart outcomes. It may help doctors predict prognosis and guide treatment for coronary narrowing.
Seoul, Songpa-guAges 19 years+ - NCT02333604Recruiting
Cancer experience registry for patients and caregivers
This registry collects information about the experiences of people with cancer and the people who care for them. Joining could help researchers better understand needs and improve support, without requiring cancer treatment changes.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT02900521Recruiting
Brest stroke and clot registry for local adults
This study is a population registry that records information from people in a specific area of Brest who had certain types of brain blood vessel events. It helps researchers understand how these conditions happen in the real world and may improve future care planning.
BrestAges 15 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT02662751Recruiting
Low-dose whole-body scan after stroke or TIA
This study looks at whether a low-dose whole-body imaging scan soon after a stroke or TIA (sometimes called a “mini-stroke”) can help doctors evaluate you. It also includes long follow-up to see how patients do over time.
MontpellierAges 18–89 - NCT02369770Recruiting
Rehab training for ankle and leg function after a stroke
This study tests a sensory-motor rehabilitation program to improve movement of the ankle and affected leg after a first stroke. It may help people regain safer, more controlled walking and leg movement.
Baltimore, MarylandAges 18–80 - NCT02845531RecruitingPhase 4
Defibrillator device vs medicines for a rare heart spasm after arrest
This trial compares an implantable defibrillator device plus best care versus best medicines alone in people who survived a cardiac arrest caused by a specific abnormal heart rhythm. It focuses on variant angina, where a heart-spasm problem can trigger dangerous rhythm events, to see which approach prevents future events.
Bucheon-siAges 18 years+ - NCT02420067Recruiting
Screening for inner-ear tumors in people with Von Hippel-Lindau
This trial focuses on checking whether a specific inner-ear tumor (called an endolymphatic sac tumor) can be found earlier in people with Von Hippel-Lindau (vHL) disease. It may help doctors detect problems sooner so you can discuss treatment options earlier, if needed.
Copenhagen, Copenhagen NAges 15 years+ - NCT02621216Recruiting
Emotional stress check during heart stent procedure
This study looks at how emotional stress affects people during and around a heart stent procedure. It may help improve support for patients who feel anxious or stressed during coronary interventions.
Tilburg, North BrabantAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
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- Immune system & allergy
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.