Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07709858Recruiting
Outcomes after TAVR for severe aortic valve disease
This is a registry study that tracks how people do after a TAVR procedure for a severely narrowed aortic heart valve. It helps doctors learn more about long-term outcomes and improve care for future patients.
SeoulAges 18 years+ - NCT07712445Recruiting
Testing a clot-busting drug coated with platelet membranes
This study tests a new way to deliver a clot-dissolving drug called tenecteplase. The drug is coated with platelet membranes to target blood clots in arteries. It may offer a safer, more effective treatment for heart attack patients and is also enrolling healthy volunteers for comparison.
Nanjing, JiangsuAges 18–75 - NCT07712900Recruiting
Nutrition counseling for diabetes and high blood pressure
This trial tests whether nutrition counseling helps people who have both type 2 diabetes and high blood pressure. It aims to improve their heart and metabolic health.
DessieAges 18 years+ - NCT07713537Recruiting
Stroke risk score for AF patients on blood thinners
This study is testing a new scoring system to predict stroke risk in people with atrial fibrillation who are taking DOAC blood thinners. The goal is to help doctors personalize treatment and prevent blood clots.
Barcelona, BarcelonaAges Any age - NCT07707037Recruiting
Helping parents cope after a child's cardiac arrest
This study tests if providing clearer information to parents after their child's cardiac arrest can reduce fear and anxiety. It is for parents of children under 17.5 years old who are expected to leave the hospital soon.
Philadelphia, PennsylvaniaAges birth–17 years - NCT07714746RecruitingPhase 3
Ivabradine for treating cardiogenic shock after heart attack
This trial tests if ivabradine, a drug that lowers heart rate, can help patients in cardiogenic shock after a type of heart attack called STEMI. It is for patients with a fast heart rate (at least 100 beats per minute) who cannot take beta-blockers.
KarachiAges 18–75 - NCT07707427Recruiting
Comparing two guidewires for twisted wrist arteries during heart tests
This trial compares two different types of thin wires (guidewires) used during a coronary angiogram to see which one works better when your wrist artery has a twist or loop. The goal is to make the procedure smoother and safer for people with this common variation.
PátraiAges 18 years+ - NCT07708805Recruiting
Heart blood flow imaging study
This study tests a special heart scan that measures blood flow to the heart muscle. It may help doctors decide if your heart blockages need treatment or if medication is enough.
Orléans, LoiretAges 18 years+ - NCT07711106Recruiting
Comparing expert IVUS to standard IVUS for left main artery stenting
This study compares two ways of using a special ultrasound camera (IVUS) inside your heart's main artery during stenting. The goal is to see if a new 'expert' computer system helps the doctor place the stent better than the standard IVUS method. It may help people with blockages at the Y-shaped split of the left main artery.
Saint PetersburgAges 18 years+ - NCT07711457Recruiting
Extended reality to guide brain bypass surgery
This trial tests whether extended reality (XR) technology can help surgeons more precisely plan and perform bypass surgery for people with moyamoya disease or blocked carotid arteries. It may make the procedure safer and more effective.
TaipeiAges 18–85 - NCT07709780RecruitingPhase 3
Comparing two blood thinners for left ventricle blood clots
This trial compares the blood thinner apixaban to warfarin for treating blood clots in the main pumping chamber of the heart (left ventricle). The goal is to see which medicine is better at preventing strokes and other complications.
Tucson, ArizonaAges 18 years+ - NCT07709208Recruiting
Mitral valve repair for leak that worsens with exercise
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
DüsseldorfAges 18 years+ - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT05826665Recruiting
Study of heart rhythm mapping during AF ablation
This is an observational study that looks at how a special heart mapping system may affect the procedure and outcomes for people having ablation for persistent atrial fibrillation (AF). It may help doctors better understand what works best and how procedures turn out.
Jonesboro, ArkansasAges 18–80 - NCT06055751Recruiting
Heart rhythm monitoring after aortic valve replacement
This trial studies people who had a heart valve procedure called TAVI and later had a heart rhythm problem. You will get a tiny heart monitor placed under your skin to track your heart rhythm over time and help doctors understand how common these problems are.
Kansas City, MissouriAges 18 years+ - NCT05951101Recruiting
Device to close an irregular heartbeat heart pocket safely
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
Parkville, VictoriaAges 18 years+ - NCT06644443RecruitingPhase 1/Phase 2
BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma
This trial tests a new kind of immunotherapy that uses your own immune cells, called CAR-T cells, to target two specific markers (BCMA and GPRC5D) found on myeloma cells. It's for people whose multiple myeloma has come back or stopped responding to earlier treatments.
Shenzhen, GuangdongAges 18–75 - NCT06457217Recruiting
MRSI for minor stroke with large artery blockage
This study uses a special MRI technique (called MRSI) to look at brain chemistry in people who have had a minor stroke due to a blocked large artery. The goal is to see if the scan can help doctors better understand the stroke and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT06632834RecruitingPhase 2
Targeted treatment study for dilated cardiomyopathy
This study tests whether a personalized treatment approach can improve heart function in people with dilated cardiomyopathy (a condition where the heart becomes enlarged and weak). It focuses on patients who still have low heart function despite standard medications.
Taipei County, Zhongzheng DistrictAges birth–99 years - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT06644963Recruiting
Impella heart pump study: safety and complications
This study reviews how well people tolerated the Impella heart pump during cardiogenic shock and what complications occurred. It looks at past cases from 2010 to 2022 to help doctors understand the safety of this device.
MontpellierAges 18 years+ - NCT04981184Recruiting
Testing muscle signals to predict walking recovery after stroke
This study looks at surface muscle electrical signals (from electrodes on the skin) to understand and predict how well your balance and walking may improve after a first stroke. You might benefit by learning more about your recovery and by helping researchers find better ways to track progress.
KaunasAges 18–89 - NCT04410003RecruitingPhase 1
Stool-sample capsules to study gut microbiome in unexplained atherosclerosis
This early-phase study tests whether taking stool-based capsules can change gut bacteria in people with severe atherosclerosis that can’t be explained by usual risk factors. Researchers also measure related metabolic (body chemistry) and microbiome (gut bacteria) changes to see how this approach might help.
London, OntarioAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.