Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07074847Enrolling by invitation
Heart artery microcirculation and metabolism study
This trial looks at the tiny blood vessels in the heart and how they work in people who have no major blockages. It may help understand chest pain that isn't caused by large artery narrowing.
Xi'an, ShaanxiAges 18–80 - NCT07306949RecruitingPhase 4
Acoramidis for transthyretin cardiac amyloidosis
This trial tests a new medicine called acoramidis for people with a heart condition caused by a protein called transthyretin. It includes people who are newly diagnosed or who are already taking another drug (tafamidis) and may benefit from switching. The goal is to see how well acoramidis works and how it affects heart-related measures.
Bunkyō CityAges 18–100 - NCT07065760Recruiting
Modified stent grafts for certain aortic aneurysms near the kidneys
This trial tests a modified stent graft for treating aneurysms that are located near the kidneys (juxtarenal). It aims to see if this doctor-customized approach works well for patients who have certain sizes or symptoms, including emergency cases.
Salt Lake City, UtahAges 18 years+ - NCT06572943Recruiting
Moderate exercise during pregnancy and heart health
This study looks at whether doing moderate exercise during pregnancy is safe and helpful for both mom and baby's heart health. If you are in your first trimester and do not have any high-risk conditions, you might be able to join.
IoanninaAges 18 years+ - NCT07208006Recruiting
Early cholesterol-lowering drug after heart attack
This trial tests whether giving a powerful cholesterol-lowering drug (PCSK9 inhibitor) very early after a heart attack can help prevent further heart problems. It is for people who have had a recent heart attack and have blockages in more than one heart artery.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT07059793Recruiting
Study of a new mitral valve replacement for heart patients
This trial is testing a replacement valve (called MITRIS) for people whose own mitral valve or a previous artificial valve is not working well. The goal is to see how well the valve works over time after it is implanted.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06574113Recruiting
Testing a new blood pressure patch without a cuff
This study tests a wearable patch that measures blood pressure without needing an inflatable arm cuff. It could make monitoring easier and more comfortable.
Woodland Hills, CaliforniaAges 18 years+ - NCT06861153Recruiting
Study on eating more beans and lentils for heart health
This trial looks at whether eating more beans, lentils, chickpeas, and peas (called pulses) over 12 weeks can improve your heart and metabolic health. It is for people who currently eat less than 1.5 cups of these foods per week and are willing to add more to their diet.
Tucson, ArizonaAges 18–75 - NCT07045064Recruiting
Exercise during dialysis for heart health
This study compares two types of exercise (aerobic vs. resistance training) done during hemodialysis sessions, and looks at how they affect a blood test related to heart disease risk.
Cairo, Select StateAges 40–60 - NCT06800781Recruiting
Chest tube duration to prevent afib after heart surgery
This trial tests if leaving a chest tube in a little longer after heart surgery can lower the chance of developing atrial fibrillation (an irregular heart rhythm). It's for people having certain planned heart surgeries who have not had this rhythm problem before.
LundAges 18 years+ - NCT06813989Recruiting
Carotid Blood Flow in Pregnant Women
This study measures blood flow in the carotid artery (a major neck artery) during pregnancy and cesarean delivery. It aims to understand how pregnancy affects blood flow, which may help improve care for mothers.
IstanbulAges 20–40 - NCT05826444Recruiting
Study of heart transplant micro-vessel disease using special tests
This trial is for people who have had a heart transplant and are having symptoms or need routine invasive check-ups. It tests an approach aimed at better understanding and monitoring “micro-vessel” problems in the transplanted heart.
BerlinAges Any age - NCT07036926Recruiting
AI video instructions for mitral valve surgery
This study tests a video-based, AI-generated tool that gives you simple instructions before and after your mitral valve repair surgery. It’s designed to help you feel prepared and recover well at home.
Los Angeles, CaliforniaAges 18 years+ - NCT07037043RecruitingPhase 3
Steroid medicines for high-risk heart surgery patients
This trial tests whether adding two common medicines, hydrocortisone and fludrocortisone, to standard care can help people who are at higher risk during planned heart surgery. It aims to see if this combination can reduce serious complications after surgery.
AmiensAges 18 years+ - NCT06862427Recruiting
Healthy lifestyle app for firefighters
This study tests a smartphone app that helps firefighters adopt healthier habits like better eating, exercise, and stress management. It aims to see if using the app can improve your overall health and well-being.
TaipeiAges 20 years+ - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years - NCT07035795Recruiting
Heart and body signal recording study
This study records heart and other body signals from people with medical conditions. It aims to better understand how these signals relate to health.
Hong KongAges 18 years+ - NCT07033715Recruiting
Exercise for hereditary ATTR amyloidosis in Portugal
This trial tests whether a structured exercise program can help people with hereditary ATTR amyloidosis (a condition that affects nerves and organs). It is for people in Portugal with early to moderate disease who can safely exercise.
Maia, Porto DistrictAges 18 years+ - NCT07253688RecruitingPhase 3
Rifampin for staph infections on artificial heart valves
This trial tests adding the antibiotic rifampin to standard treatment for staph infections on prosthetic heart valves. It aims to see if this combination improves outcomes.
Montreal, QuebecAges 18 years+ - NCT07029841Recruiting
Catheter therapy study for acute pulmonary embolism patients
This study follows patients in Hong Kong who are treated with catheter-based therapy for acute pulmonary embolism. It aims to understand how well this treatment works.
Hong Kong, Hong KongAges 18 years+ - NCT07518524Recruiting
Fast Recovery After Heart Valve Surgery
This trial compares two recovery approaches after heart valve surgery: one that wakes you up very quickly in the operating room, and one that's slightly less aggressive. Both use techniques that avoid large chest incisions. The goal is to see which approach gets you breathing on your own sooner and helps you recover faster.
Legnano, ItalyAges 18 years+ - NCT07617259Recruiting
Ultrasound guidance for heart catheterization through wrist artery
This study compares two ways of accessing the heart's blood vessels through the wrist artery during a heart imaging procedure. Researchers will test whether using ultrasound to guide the needle improves the success and safety of the procedure.
PátraiAges 18 years+ - NCT07221045Recruiting
Food as medicine for food-insecure families in rural North Carolina
This study tests whether providing fresh produce boxes and nutrition classes helps families in rural North Carolina who struggle with food access. If you are a parent or caregiver of an 8–14-year-old and live in a participating county, you may qualify.
Raleigh, North CarolinaAges 8–64 - NCT07019454Recruiting
Custom stent graft for aneurysms near the kidneys
This study tests a doctor-modified stent graft to treat a type of abdominal aortic aneurysm (just above the kidneys). It may be an option if your aneurysm is large, growing, or causing symptoms, and standard devices aren't suitable.
Springfield, MassachusettsAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.