Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT05386342Recruiting
Study of a catheter used to remove blood clots
This study looks at whether a specific over-the-wire catheter (TufTex) is safe and works well when doctors remove blood clots (embolus/thrombus) during surgery. You might join if you’re having a planned clot-removal procedure and other clot-dissolving medicines have not worked or can’t be used.
BrandenburgAges 18 years+ - NCT06498089RecruitingPhase 4
Comparing tailored vs. standard treatment for active Takayasu's arteritis.
This trial compares a personalized treatment plan based on your specific disease markers to standard care, aiming to find which is more effective and safer for active Takayasu's arteritis. It may help researchers learn how to better control inflammation and prevent flares.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06023888Recruiting
Heart rhythm analysis for persistent atrial fibrillation
This study tests a new way to analyze heart signals in people with long-standing atrial fibrillation that hasn't gotten better with medication. It may help doctors understand your heart rhythm better and guide future treatments.
TaipeiAges 20–80 - NCT06538831Recruiting
Ultra-processed foods and heart health
This study looks at how eating ultra-processed foods (like packaged snacks and sugary drinks) affects heart health markers such as cholesterol and blood pressure. If you are generally healthy and have a stable weight, you may be able to join.
Québec, QuebecAges 18–75 - NCT07701590Recruiting
New wound dressings for hard-to-heal leg and foot ulcers
This study tests a special amniotic membrane wound dressing compared to a synthetic wound matrix for stubborn diabetic foot ulcers or venous leg ulcers. It may help if your wound has not been healing well for over a month.
San Diego, CaliforniaAges 18 years+ - NCT07701798Recruiting
AI-written information for hemorrhoid care
This study tests whether AI-written educational information helps people with hemorrhoids who are getting first-line (non-surgical) care. It aims to see if this information improves your understanding and symptoms.
Sanliurfa, ŞanlıurfaAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT07705607RecruitingPhase 3
Comparing MK-8748 to standard treatment for diabetic eye swelling
This trial tests a new medicine (MK-8748) against an existing treatment (aflibercept) for people with diabetic macular edema, which causes vision loss due to swelling in the back of the eye. The goal is to see which works better to improve or protect vision.
Winter Haven, FloridaAges 18 years+ - NCT07697950Recruiting
Blood pressure cuff accuracy study for adults
This study tests how well a new blood pressure cuff measures blood pressure compared to a standard arterial line. If you already have an arterial line as part of your care, you may be able to help us see if the cuff is accurate.
HelsinkiAges 18 years+ - NCT07705555RecruitingPhase 3
Comparing a new eye injection to standard treatment for diabetic eye swelling
This trial tests if a new medicine (MK-8748) works as well as or better than the usual treatment (aflibercept) for people with diabetic macular edema, a condition that causes vision loss from diabetes-related swelling in the back of the eye.
Glendale, CaliforniaAges 18 years+ - NCT07704424Recruiting
Testing a heart pump for severe right heart failure
This trial is evaluating a new temporary heart pump called CorVad for people who develop severe right heart failure shortly after heart surgery, a heart attack, or a heart transplant. The pump is designed to help the right side of the heart pump blood when medications are not enough.
Hefei, AnhuiAges 18 years+ - NCT07698951Recruiting
Testing a new device to close PFO after stroke
This trial tests a new device to close a PFO (a small hole in the heart) in people who have had a stroke caused by a blood clot passing through that hole. The goal is to see if the device can prevent another stroke.
BelgradeAges 18–65 - NCT06645990Recruiting
Comparing Heart Pumps for Shock With ECMO
This study compares two support devices (Impella vs. IABP) for people with cardiogenic shock who are already on ECMO. It looks at how well the left side of the heart recovers when one of these devices is added.
MontpellierAges 18 years+ - NCT06647251Recruiting
Comparing different radiofrequency modes for atrial fibrillation ablation
This trial tests three different ways of delivering radiofrequency energy using a specific catheter (QDOT) during a first-time procedure to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to find which method works best for patients with recent or short-lasting AF episodes.
Paris, ParisAges 18 years+ - NCT07701512RecruitingPhase 2
Febuxostat for brain bleed patients managed without surgery
This trial tests if febuxostat, a medicine used for gout, can help people recover from a brain bleed (intracranial hemorrhage) when surgery is not needed. It may reduce inflammation and improve outcomes.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07702760Recruiting
Improving heart failure care with reduced pumping ability
This study evaluates how well doctors follow guidelines for treating heart failure with reduced ejection fraction (HFrEF). It aims to improve the quality of care you receive during your regular clinic visits over the next year.
RotterdamAges 18 years+ - NCT07702123Recruiting
Physical activity study for women with Behcet's and metabolic syndrome
This study tests if a physical activity program helps women who have both Behcet's disease and metabolic syndrome. It aims to improve their health and well-being.
Giza, DokkiAges 40–50 - NCT07704918Recruiting
Study: Lowering cholesterol during melanoma immunotherapy
This study tests whether giving aggressive cholesterol-lowering medication to people starting immunotherapy for melanoma can improve heart health. It may help reduce the risk of heart problems during cancer treatment.
Aurora, ColoradoAges 55 years+ - NCT07702643Recruiting
Walking practice at home after stroke
This study tests a home-based walking program for people who have recently had a stroke. It combines behavioral coaching with guided stepping exercises to help improve mobility and confidence when walking after returning home from the hospital.
Calgary, AlbertaAges 50 years+ - NCT07703618Recruiting
Does arm massage and tapping prevent IV irritation?
This study tests whether gentle massage and tapping on your arm near the IV site can lower the chance of irritation (phlebitis) from the IV. If you qualify, you would do simple hand and arm motions for a short time each day while you have the IV.
Bogotá, Bogota D.C.Ages 18–110 - NCT07704671Recruiting
Analyzing past results for iliac branch device
This trial re-analyzes data from past studies of people who had a procedure using a special fabric tube (Gore Iliac Branch Endoprosthesis) to treat aneurysms in the main belly or hip arteries. It aims to gather all available information to better understand how well the device works.
Arnhem, GelderlandAges Any age - NCT07698964Recruiting
CARE: A program to build resilience and heart health
This study tests a program called CARE designed to help women manage stress and reduce heart disease risk. Participants will learn skills to build resilience and improve their overall well-being.
Edinburg, TexasAges 18–49 - NCT07704840RecruitingPhase 2
Testing a new pill for post-stroke arm stiffness
This study tests an experimental pill (BMS-986368) that targets two brain chemicals to reduce muscle stiffness after a stroke. It's for people who had a stroke in the last 4 to 18 months and have moderate tightness in their elbow and wrist.
Elkins Park, PennsylvaniaAges 18–80 - NCT07705906Recruiting
Robot-assisted leg training for mobility recovery
This trial tests a robot device to help people with leg weakness from stroke, spinal cord injury, or joint surgery improve their walking. It may be a good option if you are medically stable and can work with the robot safely.
Dhaka, Dhaka DivisionAges 18–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.