Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT05320926Recruiting
Clopidogrel vs aspirin after heart stent treatment
This trial compares two blood-thinning medicines—clopidogrel and aspirin—after you have finished a short period of dual therapy following a special type of drug-eluting heart stent. It may help find which medicine works better and is safer for preventing future heart problems.
SeoulAges 19–84 - NCT02901184RecruitingPhase 3
Spironolactone start study for heart failure with preserved pumping
This trial tests whether starting spironolactone helps people with heart failure symptoms when the heart pumps “preserved” (not severely reduced). Participants are assigned to start spironolactone or usual care so researchers can see if it improves outcomes.
Alexander City, AlabamaAges 50–99 - NCT03687580Recruiting
At-home laser treatment for diabetic foot ulcers
This trial tests whether an at-home low-level laser can help diabetic foot ulcers heal. You may be able to do treatments yourself or with a caregiver, but you must meet specific wound, circulation, and safety requirements.
Toronto, OntarioAges 18–95 - NCT04800913Recruiting
Imaging tests during left atrial appendage closure
This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.
BudapestAges 18 years+ - NCT07689058RecruitingPhase 2
CAR-T therapy for relapsed or refractory multiple myeloma
This trial tests a CAR-T cell therapy for multiple myeloma that has come back or not responded to at least three prior treatments. It aims to see if this immunotherapy can help control the disease.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT07690436Recruiting
Eye imaging for detecting a type of heart disease
This study uses retinal imaging (pictures of the back of the eye) and OCT scans to look for signs of a specific heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). It may help doctors find this condition with an eye exam instead of more invasive tests.
Palo Alto, CaliforniaAges 18 years+ - NCT07695701RecruitingPhase 4
Heart imaging study for a new ATTR-CM treatment
This trial uses heart scans to see how the drug acoramidis affects heart structure and function in people with a specific type of heart disease called ATTR cardiomyopathy. It may help doctors understand if the treatment is working.
St Louis, MissouriAges 18–80 - NCT07697599RecruitingPhase 3
Blood clot prevention study for people getting a PICC line
This study tests two experimental drugs, REGN7508 and REGN9933, to see if they can safely prevent blood clots in the arm or chest in people who need a PICC line. If you are getting a PICC for treatments like chemotherapy or antibiotics, you may be able to join.
TbilisiAges 15 years+ - NCT07691606RecruitingPhase 1
Testing a new drug for B-cell lymphoma that has come back
This trial tests a new medicine called ARC-02 for people with certain types of B-cell non-Hodgkin lymphoma (a cancer of the immune system) that has not responded well enough to at least two prior treatments. The goal is to see if this drug can help when other options are no longer working.
Los Angeles, CaliforniaAges 18 years+ - NCT06475105RecruitingPhase 4
Acetazolamide and Furosemide for Acute Heart Failure
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Semarang, Central JavaAges 18 years+ - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT07693049Recruiting
Exercise training for heart failure with preserved pumping ability
This trial tests whether high-intensity interval training can improve heart function and fitness in people with a type of heart failure where the heart pumps normally but doesn't fill properly. You will do supervised exercise sessions to see if it helps you feel better and be more active.
BeijingAges 35–70 - NCT07692958Recruiting
Thinking skills training for children with heart defects
This trial tests a program to help children born with heart problems improve their thinking and planning skills (called 'executive function'), which may be affected by their heart condition or surgery. It is for children aged 9 to 13 who had heart surgery before age 1 and show some difficulties with these skills.
Zurich, Canton of ZurichAges 9–13 - NCT07693348Recruiting
Daily stair climbing for heart rehab
This trial tests whether climbing stairs every day helps people with heart problems recover better during cardiac rehab. If you are in a rehab program and can walk without help, you may be able to participate.
ArrasAges 18 years+ - NCT07696884Recruiting
Vascular graft and endograft infection study
This study looks at how the body responds to infections in artificial blood vessels (vascular grafts or endografts). It may help understand why some people get infections and how to better treat them.
AarhusAges 18 years+ - NCT07692191Recruiting
Spinal stimulation to help exercise after spinal cord injury
This study tests whether a non-invasive device that sends mild electrical pulses to the spinal cord can improve your ability to exercise. It is for people who have had a spinal cord injury for at least a year and are medically stable.
Winnipeg, ManitobaAges 18–70 - NCT07688746RecruitingPhase 1
Helping premature babies heal brain injury
This trial tests a treatment for brain injury in premature babies born before 32 weeks. It aims to protect and repair white matter, the part of the brain that helps nerve cells communicate.
San Francisco, CaliforniaAges 3 weeks–5 months - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07691502Recruiting
Using CT scans before angioplasty to plan treatment
This trial tests if using a special heart CT scan (CCTA with FFRCT) before a planned angioplasty can help doctors better plan where to place stents. You may be eligible if you have a narrowing in one or two heart arteries that haven't been treated before.
Minneapolis, MinnesotaAges 22 years+ - NCT07695376Recruiting
Caramel study on women's health with digital devices
This study follows women aged 40–60 to see how smartphones and wearable devices can help monitor health over time. It aims to improve care by using technology that fits easily into daily life.
BogotáAges 40–60 - NCT07693699Recruiting
Helping with home blood pressure monitoring in primary care
This study provides support for getting and using a home blood pressure monitor if you have high blood pressure. It tests a training pathway to help you track your blood pressure at home.
Chicago, IllinoisAges 18 years+ - NCT07691411Recruiting
Smartphone app for stroke recovery support
This study uses a smartphone app to help you manage your recovery after a stroke. It sends you quick questions and tips throughout the day to support your self-care and well-being.
Hong Kong, Hong KongAges 18 years+ - NCT07695883RecruitingPhase 3
Vitamins and minerals for teen girls' health
This study tests whether giving teen girls extra vitamins and minerals improves their growth and health. It may help girls who are still growing and living at home.
Rangpur CityAges 10–18
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.