Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06738992RecruitingPhase 4
Early aspirin after mitral valve repair: safety and effectiveness
This study tests whether starting aspirin early after mitral valve repair is safe and effective compared to standard care. It's for adults who have had this heart surgery and have a low risk of bleeding or stroke.
Guangzhou, GuangdongAges 18–85 - NCT06588452Recruiting
AI vs manual chart review for heart failure studies
This trial tests whether a computer program (AI) can help doctors review patient charts faster than doing it by hand. It looks at people with heart failure to see if AI can correctly identify who might qualify for other studies.
Boston, MassachusettsAges 18–90 - NCT06587854Recruiting
Study on fluid congestion in acute heart failure patients
This study looks at different patterns of fluid buildup in people with acute heart failure. It aims to understand how these patterns relate to treatment with water pills (diuretics) and may help improve care.
GroningenAges 18 years+ - NCT07016022Recruiting
Heart and lung test before chest surgery helps predict risks
This study checks if a simple test of your heart and breathing before chest surgery can help predict problems after the operation. It looks at people having surgery for lung, esophagus, stomach, or chest tumors.
Ottawa, OntarioAges 18 years+ - NCT05993481Enrolling by invitation
Blood pressure measurement and hypotension risk during surgery
This trial tests if noninvasive blood pressure cuff measurements before surgery can help predict low blood pressure during surgery for people having non-cardiac surgery.
Konya, MeramAges 18 years+ - NCT07012668Recruiting
Treatments for heart-brain conditions and post-surgery stroke
This trial is studying different treatments for people who have conditions that affect both the heart and brain, or who have had a stroke or other brain blood vessel problem after heart surgery. The goal is to find out which treatments work best and see what factors affect the results.
BeijingAges 18 years+ - NCT06590532Recruiting
Testing a new X-ray system for vascular surgery
This study compares a new automated X-ray system (mobile hybrid room) with the current standard equipment used during vascular surgery. It aims to see if the new system is more effective and cost-efficient for treating narrowed or widened blood vessels in the belly area.
Besançon, BesançonAges 18 years+ - NCT07010003Recruiting
Ear acupressure for anxiety and pain during heart surgery
This trial tests whether small ear acupressure beads can help reduce anxiety and pain in adults having planned heart surgery. The beads are placed on specific ear points and are easy to use.
StuttgartAges 18 years+ - NCT07009834Recruiting
Solving challenges with conduction system pacing
This trial is testing a special way to pace the heart's natural electrical system, which may help people who need a pacemaker for certain heart-block conditions or for heart failure treatment. It aims to make pacing work better.
LondonAges 18–100 - NCT06866756Recruiting
Comparing two drug-coated balloons for heart artery treatment
This trial is comparing sirolimus and paclitaxel drug-coated balloons to treat new blockages or restenosis (re-blockage) in heart arteries. It aims to see which type of balloon works better for opening arteries without leaving a metal stent behind.
Vigo, PontevedraAges 18 years+ - NCT07006636Recruiting
Watermelon for heart health in postmenopausal women
This study tests whether eating watermelon can improve heart health and blood pressure in postmenopausal women with slightly elevated blood pressure. It lasts about 4 weeks and involves eating watermelon as part of your usual diet.
Los Angeles, CaliforniaAges Any age - NCT07301307Recruiting
Blood pressure and fluid management during surgery
This trial tests a new tool that helps doctors manage fluids and blood pressure during surgery. It uses a special index (HPI) and computer-assisted fluid management to keep your blood pressure stable, which may reduce complications.
Athens, AtticaAges 18 years+ - NCT07005193Recruiting
Cleaner cooking and ventilation for better heart and lung health
This study tests if switching to cleaner LPG gas stoves and adding kitchen fans can reduce indoor air pollution and improve your heart and lung health. You would be asked to use a new stove and fan, and we will check your health over time.
Zhumadian, HenanAges 18–75 - NCT07005050Recruiting
Kidney nerve treatment for high blood pressure pilot study
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
Birmingham, AlabamaAges 21–80 - NCT07004569Recruiting
Angiolite Registry Study for heart artery stents
This study is testing a new type of stent for people with a blockage in the main artery of the heart. It aims to see how well the stent works and if it's safe.
Hong Kong, ShatinAges 19 years+ - NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT06595290Recruiting
Faster medication increase for heart failure with weak pumping
This trial tests a new, faster way to increase heart failure medications during a hospital stay, aiming to get patients on the right doses sooner. It is for people with weak heart pumping (ejection fraction 40% or less) who are currently in the hospital for heart failure and are on low doses of standard medications.
Long Xuyen, An GiangAges 18–75 - NCT07001943Recruiting
Blood flow in stomach and gut injury in ICU patients
This trial checks if changes in blood flow to the stomach and intestines can predict gut injury in critically ill patients who need feeding through a tube. It uses a safe ultrasound test at the bedside.
Beijing, Beijing MunicipalityAges 18–80 - NCT07299227Recruiting
Study on heart and lung effects of BPA in CTEPH
This study uses special heart scans (CMR with 4D flow) to see how a procedure called BPA affects blood flow in the heart and lungs for people with a rare type of high blood pressure in the lungs (CTEPH). It may help doctors understand how well BPA works beyond just symptoms.
Bad Nauheim, HesseAges 18–99 - NCT06997224Recruiting
Breathing exercises after heart valve surgery
This trial tests two breathing exercises (Triflow and deep breathing with cough) to see if they help patients recover lung function after mitral valve replacement surgery. It may help you breathe better after your procedure.
IstanbulAges 18–80 - NCT06715449RecruitingPhase 2/Phase 3
Testing empagliflozin after a stroke with unknown cause
This trial tests if a diabetes drug called empagliflozin can help the heart's left atrium work better in people who have had a stroke with no known cause. You may join if you are getting a heart monitor device implanted to look for hidden irregular heartbeats.
Cambridge, CambridgeshireAges 18 years+ - NCT06742008Recruiting
Can antibodies predict heart damage after viral myocarditis?
This study looks at whether certain antibodies in your blood can predict if viral myocarditis will lead to a weakened heart muscle (dilated cardiomyopathy). It may help doctors understand your risk and plan better care.
Wuhan, HubeiAges 18–75 - NCT06995495Recruiting
Wearable devices to help manage heart attack recovery
This trial tests whether a wearable device can help manage recovery after a heart attack. It might help you track your health and alert your care team if there is a problem.
ShanghaiAges 18–75 - NCT06994221Recruiting
Heart function study after heart attack with aneurysm
This trial looks at how heart scarring after a major heart attack affects the heart's shape and function. It might help people who developed a bulge (aneurysm) in the heart wall after their attack.
ShanghaiAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.