Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06937658Recruiting
Better remote care for heart device patients
This study tests a new alert system for people with pacemakers or defibrillators that can send information directly to your care team. The goal is to improve how quickly problems are found and treated.
Boston, MassachusettsAges 18 years+ - NCT06939803Recruiting
AI tool to prevent blood clots in hospitalized patients
This trial tests an AI tool that helps doctors prevent blood clots in hospitalized patients. If you are admitted to a participating Vanderbilt hospital, you may be part of this study.
Nashville, TennesseeAges Any age - NCT05956418RecruitingPhase 4
Testing centhaquine for low-blood-pressure shock patients
This trial studies whether centhaquine is safe and can help treat adults in the emergency room or ICU who have hypovolemic shock (dangerously low blood pressure from low circulating fluid). Participants receive the usual shock care, and the study adds this medicine to see if outcomes improve.
Nellore, Andhra PradeshAges 18 years+ - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT06882733Recruiting
TENS therapy for leg blood flow in healthy adults
This trial tests whether a gentle electrical stimulation (TENS) applied to the leg muscles and nerve clusters can improve blood flow behind the knee. It looks at immediate effects and might help understand better ways to support circulation.
Kaohsiung City, TaiwanAges 18 years+ - NCT03521050Recruiting
Registry study of ICD leads implanted since 2006
This study keeps a long-term record of people who get an ICD (a device that helps treat dangerous heart rhythms) and its lead. It may help doctors learn how ICD leads perform over time.
LucerneAges Any age - NCT06884046Recruiting
Supporting parents of babies with heart conditions
This study offers support to parents whose baby is diagnosed with a heart condition before birth and will need surgery shortly after birth. The goal is to help parents manage stress during this difficult time.
Pessac, FranceAges birth–4 weeks - NCT06013046Recruiting
Wheelchair exercise program for better heart health
This study tests a physical activity training program designed for wheelchair users to improve heart and metabolic health. You will attend weekly exercise sessions and your fitness levels will be monitored throughout the program.
St Louis, MissouriAges 18 years+ - NCT05521399Recruiting
Heart transplant patients get a heart MRI check
This study renews research using heart MRI scans to learn more about heart transplant patients and compare them with healthy control scans. It may help researchers understand heart function after transplant and improve future imaging care.
Chicago, IllinoisAges Any age - NCT06348394Recruiting
Comparing heart imaging methods for a procedure to prevent stroke
This trial is testing two ways to guide a procedure that closes a small pouch in the heart to lower the risk of stroke in people with atrial fibrillation. The goal is to see if one method is as good or better than the other.
Plano, TexasAges 18–90 - NCT06931574Recruiting
Comparing two stent methods for complex heart branch blockages
This trial compares two ways of placing stents in complex blockages in heart artery branches (smaller arteries branching off main ones). It aims to see which technique works better for this specific type of blockage.
IstanbulAges 18 years+ - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+ - NCT06715371Recruiting
Heart chamber measurements during heart surgery
This study compares two types of ultrasound of the heart—one done on the chest and one done through the throat—to see if they give similar measurements. It may help people having planned heart surgery who have normal heart function.
Toronto, OntarioAges 18 years+ - NCT06919562Recruiting
Better stent placement using imaging and newer scaffolds
This trial tests if using advanced imaging (like OCT or IVUS) to guide placement of a newer type of stent (bioresorbable scaffold) can reduce future stent problems. It is for people with stable coronary artery disease who need a stent in a main heart artery.
DordrechtAges 18 years+ - NCT06887699Recruiting
AI ECG for heart attack care in emergency
This trial is testing whether using artificial intelligence to read ECGs in the emergency department helps doctors better manage heart attacks, especially under a new payment system. It may help speed up treatment and improve care.
Kaohsiung City, TaiwanAges 18 years+ - NCT07741383Recruiting
Combined procedure for severe mitral regurgitation and atrial fibrillation
This study tests whether combining a valve repair procedure with a heart rhythm reset procedure is safe and effective for people with severe mitral regurgitation and atrial fibrillation. It may help improve heart function and reduce symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT06912984Recruiting
How exercise affects blood vessels as we age
This study looks at how exercise changes blood vessels differently in older women and men. You'll be randomly assigned to either an exercise program or a no-exercise control group for a few months, and researchers will measure your blood vessel health before and after.
Aurora, ColoradoAges 18 years+ - NCT07680270Enrolling by invitation
Measuring quality of life after heart procedures
This study measures how heart procedures affect quality of life for both patients and their caregivers, using simple questionnaires.
Clermont-FerrandAges Any age - NCT07739667Recruiting
Camera-based blood pressure monitoring study
This study tests a new way to measure blood pressure using a camera, without needing a cuff. It may make checking blood pressure easier and more comfortable.
TampereAges 18 years+ - NCT07680595RecruitingPhase 1/Phase 2
Statins and folic acid for unstable carotid plaque
This trial tests if adding folic acid to a statin can help stabilize plaques in the carotid artery (neck artery) to prevent stroke. You may qualify if you have carotid plaque and are not already on certain supplements.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07229482Recruiting
Potatoes and your health: a 14-week food study
This study tests whether eating potatoes (as part of a provided diet) can improve blood sugar and heart health markers – possibly lowering your risk for type 2 diabetes.
Blacksburg, VirginiaAges 50–70 - NCT07682298Recruiting
Measuring leftover fluid in hospitalized heart failure patients
This study looks at how well we can measure leftover fluid in the body in people hospitalized for heart failure with fluid overload. It aims to help doctors better manage treatment and improve recovery.
AarhusAges 18 years+ - NCT06906250Recruiting
European registry for leg vein blood clots
This trial is a registry (a database study) that tracks people with blood clots in the large veins of their legs or abdomen. It does not test any new drug or treatment, but helps doctors learn more about these conditions.
Marseille, FranceAges 18 years+ - NCT04804124Recruiting
Study links sleep duration to heart health
This study looks at how long you sleep and your sleep patterns relate to cardiovascular (heart and blood vessel) health. You may be asked to complete health and sleep questionnaires and possibly follow a study sleep plan.
Portland, OregonAges 25–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.