Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07320339Recruiting
Blood pressure measurement differences in women of reproductive age
This study compares two ways of measuring blood pressure in women ages 18-40—one done exactly by guidelines and one done as usual in clinics. The goal is to see if the regular way gives different readings, which could affect diagnosis and treatment.
Hadera, IsraelAges 18–40 - NCT07298044RecruitingPhase 4
Switching from tafamidis to acoramidis for heart condition
This study checks how levels of a protein called transthyretin change in your blood when you switch from tafamidis to acoramidis. It is for people with a specific type of heart disease caused by abnormal protein buildup.
Sankt Pölten, Lower AustriaAges 18–90 - NCT05606432Recruiting
Movement-to-music exercise program for people with mobility limits
This study tests whether a movement-to-music exercise program at home can improve cardiometabolic health (health related to heart and blood sugar) for adults who use a wheelchair and are not already exercising regularly. You may benefit if you can exercise using your arms and can do moderate activity safely.
Birmingham, AlabamaAges 18–89 - NCT06988995Recruiting
Compassion support study for LVAD patients and caregivers
This study tests a compassion-based support program for people with a left ventricular assist device (LVAD) and their family caregivers. It aims to improve emotional well-being and reduce distress.
Gainesville, FloridaAges 18–80 - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT06985693Recruiting
AI-assisted stent placement study for heart disease
This trial tests whether a new artificial intelligence tool called Medipixel XA can help doctors place stents more precisely in blocked heart arteries. If you have coronary artery disease and need a stent, this study could be an option.
Gwangmyeong, Gyeonggi-doAges 19 years+ - NCT06984302Recruiting
Predicting outcomes in aortic surgery
This study tests a predictive algorithm for people having planned (non-emergency) aortic surgery. It looks at how well the algorithm can predict risks and help guide care.
Rome, RMAges 18 years+ - NCT06710184RecruitingPhase 4
Aspirin alone vs. aspirin plus fondaparinux before early heart catheterization in NSTEMI
This study tests whether taking aspirin alone works as well as aspirin plus a blood thinner called fondaparinux before a heart procedure in people with a specific type of heart attack (NSTEMI). It aims to find the safest and most effective treatment before an early heart catheterization.
Herning, Region MidtAges 18 years+ - NCT06208904Enrolling by invitation
Gut hormone’s role in post-meal blood pressure drops
This study tests whether a gut hormone called GIP is involved in causing blood pressure drops after eating. It may help find better treatments for people who feel dizzy or faint after meals.
Copenhagen, HellerupAges 18–85 - NCT06972784Recruiting
Heart and lung health study at Xiangya Hospital
This study looks at how heart and lung function are related over time. You may be able to join if you have had both a heart test (like an echo) and a lung test (like a breathing test) within one year of each other, and if your medical records are complete.
Changsha, HunanAges Any age - NCT06875466Recruiting
Can sauna bathing help your heart
This study looks at whether regular sauna bathing can improve health. If you qualify, you would use a sauna several times a week for a set period, and researchers will check your blood pressure and other heart risk factors.
TaurangaAges 18–70 - NCT06961136Recruiting
Herbal medicine for recovery after heart bypass surgery
This trial tests if a traditional Chinese herbal formula (Fuzheng Yangxin Prescription) can help people recover faster after coronary artery bypass surgery. It is for people who have a specific pattern of symptoms (called Qi-Yin deficiency) after their operation.
Beijing, Beijing MunicipalityAges 25–85 - NCT06360380Recruiting
Wearable device for fluid removal in heart failure
This trial tests a wearable device that removes extra fluid from your body without using the kidneys. It may help people with heart failure who still have fluid buildup despite taking high doses of water pills.
La Jolla, CaliforniaAges 21–79 - NCT06961630RecruitingEarly Phase 1
Heart protection after surgery
This trial tests if a personalized approach with blood thinners and statins can reduce heart risks after non-cardiac surgery. It is for adults 45 and older who had a heart injury during or after surgery.
New York, New YorkAges 45 years+ - NCT06957613Recruiting
A Registry for Chronic Total Heart Artery Blockages
This study is collecting information on people who have a complete blockage in a heart artery (a chronic total occlusion) and who are scheduled for a procedure to open it up. The goal is to learn more about the treatment and outcomes for these patients.
Bad Segeberg, Schleswig-HolsteinAges 18–100 - NCT06877195Recruiting
Vein graft support mesh for bypass surgery
This trial tests a mesh wrap that supports the vein grafts used in bypass surgery. It may help those grafts stay open longer, especially for the right side of the heart.
Roma, RomaAges Any age - NCT06814054Recruiting
Predicting low blood pressure after anesthesia in older patients
This study uses ultrasound measurements of the carotid artery and vena cava to predict if older patients might experience low blood pressure after going under general anesthesia for elective surgery. If successful, it could help doctors take preventive steps.
Tanta, El GharbyiaAges 65 years+ - NCT06955663Recruiting
Exercise and support for women after SCAD
This trial tests whether a personalized exercise and support program can help women recover better after a spontaneous coronary artery dissection (SCAD). If you are a woman with SCAD and stable heart function, this program may improve your strength, confidence, and quality of life.
Leicester, LeicestershireAges 18 years+ - NCT07189676Recruiting
Healthy eating study for adults with metabolic issues
This study tests how eating sustainably can improve heart and metabolic health. It looks at whether a diet with more plant-based foods and less red meat can help people with conditions like high blood pressure or prediabetes.
Copenhagen, CopenhagenAges 45–70 - NCT06950775Recruiting
Neighborhood & health study
This study looks at how living in different neighborhoods might affect health. If you recently moved to or plan to move to the Indigo Neighborhood, or currently live in the Elyson Neighborhood, you may be able to join.
Katy, TexasAges 18 years+ - NCT06702501Recruiting
Shunt device to treat heart failure with preserved ejection fraction
This trial tests a tiny tube (shunt) placed in the heart to relieve pressure and ease severe shortness of breath. It's for people with a type of heart failure where the heart pumps well but doesn't relax enough.
Rochester, MinnesotaAges 30 years+ - NCT03331380Recruiting
Low-energy MRI study for people with or without heart disease
This study tests a special MRI method that uses lower energy exposure. It aims to improve how well researchers can scan the heart and other organs while keeping the scan as safe and comfortable as possible.
Bethesda, MarylandAges 18–100 - NCT07288840Enrolling by invitation
Exercise plan for heart recovery monitored by heart rate
This study tests a special exercise program for people with heart disease or heart failure. The goal is to see if the exercises can help improve how your heart responds to activity and daily life.
Leiria, Leiria DistrictAges 18 years+ - NCT07612553Recruiting
Imaging study of calcium buildup on heart valves
This research compares two types of heart imaging scans to better see calcium deposits on the mitral valve (a valve in your heart). Researchers hope this helps doctors plan valve procedures more safely and accurately.
Milan, MilanAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.