Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07695883RecruitingPhase 3
Vitamins and minerals for teen girls' health
This study tests whether giving teen girls extra vitamins and minerals improves their growth and health. It may help girls who are still growing and living at home.
Rangpur CityAges 10–18 - NCT07693348Recruiting
Daily stair climbing for heart rehab
This trial tests whether climbing stairs every day helps people with heart problems recover better during cardiac rehab. If you are in a rehab program and can walk without help, you may be able to participate.
ArrasAges 18 years+ - NCT07693049Recruiting
Exercise training for heart failure with preserved pumping ability
This trial tests whether high-intensity interval training can improve heart function and fitness in people with a type of heart failure where the heart pumps normally but doesn't fill properly. You will do supervised exercise sessions to see if it helps you feel better and be more active.
BeijingAges 35–70 - NCT07696884Recruiting
Vascular graft and endograft infection study
This study looks at how the body responds to infections in artificial blood vessels (vascular grafts or endografts). It may help understand why some people get infections and how to better treat them.
AarhusAges 18 years+ - NCT07693816Recruiting
Finding stroke caused by small artery disease
This study looks at whether your stroke was caused by branch atheromatous disease (BAD), a type of small artery blockage. Knowing this may help choose the best treatment and prevention plan.
BeijingAges 18–80 - NCT07695545Recruiting
Lipid metabolism study in ascending aortic aneurysm
This study looks at how fat metabolism and cell energy centers (mitochondria) work in patients having surgery for an ascending aortic aneurysm. It aims to understand differences between people with bicuspid or tricuspid aortic valves.
DijonAges 18 years+ - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07688746RecruitingPhase 1
Helping premature babies heal brain injury
This trial tests a treatment for brain injury in premature babies born before 32 weeks. It aims to protect and repair white matter, the part of the brain that helps nerve cells communicate.
San Francisco, CaliforniaAges 3 weeks–5 months - NCT07691502Recruiting
Using CT scans before angioplasty to plan treatment
This trial tests if using a special heart CT scan (CCTA with FFRCT) before a planned angioplasty can help doctors better plan where to place stents. You may be eligible if you have a narrowing in one or two heart arteries that haven't been treated before.
Minneapolis, MinnesotaAges 22 years+ - NCT07689591Recruiting
Non-invasive blood flow boost for heart attack patients
This trial tests a non-invasive method to improve blood flow in the arm during a heart attack. It may help reduce heart muscle damage before the standard artery-opening procedure.
Elâzığ, ElaziğAges 18–80 - NCT07692958Recruiting
Thinking skills training for children with heart defects
This trial tests a program to help children born with heart problems improve their thinking and planning skills (called 'executive function'), which may be affected by their heart condition or surgery. It is for children aged 9 to 13 who had heart surgery before age 1 and show some difficulties with these skills.
Zurich, Canton of ZurichAges 9–13 - NCT03692598Recruiting
Transcatheter repair for leaky tricuspid valve during heart surgery
This trial studies a catheter-based repair to help fix a leaky tricuspid valve (regurgitation), especially when you’re also having another heart surgery. It aims to improve valve function and symptoms while tracking safety and outcomes.
AarhusAges 18–85 - NCT05488665Recruiting
Two-stent approach comparison for new bifurcation heart blockages
This study compares two different ways of placing two drug-eluting stents for new (de novo) coronary artery blockages that split into two branches. It may help doctors choose the safest, most effective technique for patients with specific coronary anatomy.
SeoulAges 19 years+ - NCT06596304Recruiting
How blood vessels respond to exercise with and without blood flow restriction
This study looks at how your blood vessels respond to resistance exercise (like weight lifting) with and without a technique called blood flow restriction. It compares younger and older adults to understand how aging affects these responses.
Almada, Monte Da CaparicaAges 18 years+ - NCT06655389Recruiting
Link between PLA levels and sepsis heart failure severity
This study looks at how levels of a substance called PLA relate to how severe sepsis-related heart failure is. It may help doctors understand your condition better and guide treatment.
Beijing, Beijing MunicipalityAges 50–90 - NCT06654375Recruiting
Late stroke treatment with clot removal or medication
This trial compares a procedure to remove a large blood clot from the brain (thrombectomy) with standard medical care for people who had a stroke 24 to 72 hours ago but still have some blood flow around the clot. It aims to see if the procedure can help improve recovery even when started later than usual.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05812963Recruiting
IVUS vs FFR to guide stents after heart attacks
This trial compares two ways of measuring blood flow inside the heart arteries (IVUS vs FFR) to help decide which non–culprit artery narrowings need a stent after a recent heart attack. It may help doctors choose the best targets for PCI and avoid unnecessary procedures.
GwangjuAges 19 years+ - NCT04641286Recruiting
Tracking changes in quick recovery after acute stroke
This study looks at how stroke symptoms and recovery change over time soon after an acute stroke. It may help doctors better predict outcomes and improve care planning for stroke patients.
LondonAges 18 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06262828Recruiting
Heart health study for Chinese with past CVD event
This study looks at heart health in Chinese patients who have had a past cardiovascular event. If you qualify, you'll help researchers learn more about heart disease and how to improve care.
Hong KongAges 18–80 - NCT06655922Recruiting
FAPI scan to assess chronic total heart artery blockages
This study is testing whether a special type of PET scan (called FAPI) can better see and understand fully blocked heart arteries (chronic total occlusions). If you're scheduled to have angioplasty to open such a blockage, this imaging might help guide the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.