Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT05838508Recruiting
Exercise timing study to improve heart and body health
This trial studies how different exercise patterns affect heart-related and metabolic health (things like blood sugar and cholesterol). You may be asked to follow a specific exercise schedule and related testing if you’re healthy enough to exercise safely.
Boston, MassachusettsAges 18–45 - NCT06984276Recruiting
Nerve blocks for pain relief in children having heart surgery
This study compares two different ultrasound-guided numbing injections (pectoral nerve block vs. transverse thoracic plane block) to see which provides better pain control for children aged 6 months to 7 years undergoing heart surgery through a chest incision with a heart-lung machine.
CairoAges 6 months–7 years - NCT06986967Recruiting
Comparing Blood Flow Methods During Aortic Arch Surgery
This study compares two methods of supplying blood to the brain during surgery on the main artery from the heart (aorta) and the aortic arch. It may help determine the safest way to protect the brain during cooling and surgery.
Durham, North CarolinaAges 18 years+ - NCT05655065Recruiting
Testing higher blood pressure to protect kidneys in shock
This trial studies whether aiming for a higher average blood pressure (using medicines) can better protect kidney function in critically ill adults with shock. You may be asked to have close kidney and heart monitoring while receiving blood-pressure support.
AngersAges 18 years+ - NCT06272045Recruiting
Early heart health support for moms and babies
This study tests a program that helps pregnant women in home visiting take care of their heart health and their baby's health. It is available to women who are pregnant or just had a baby and are in a participating home visiting program.
Birmingham, AlabamaAges 18 years+ - NCT06260579Recruiting
Home exercise program after kidney transplant
This study tests whether a home exercise program, especially with higher intensity, can help people recover better after a kidney transplant. You would exercise on a stationary bike at home, with guidance from a team.
GhentAges 18 years+ - NCT07244809Recruiting
Study on stress history and blood vessel health in young adults
This study tests whether early-life stress affects blood vessel function in young adults by looking at a type of cell stress called oxidative stress. It involves measuring how well your blood vessels work and may help understand why some people have higher heart risks.
Iowa City, IowaAges 18–29 - NCT06228365Recruiting
Minimally invasive vein surgery with sedation
This trial tests a new way to perform minimally invasive surgery for superficial venous insufficiency (a common vein problem) using sedation and local anesthesia. It aims to see if using a virtual reality headset during the procedure helps patients feel more comfortable.
Saint-JeanAges 18 years+ - NCT06197347Recruiting
Web program to help older adults be more active after heart treatment
This study tests a nurse-led website designed to help older adults become more physically active after heart surgery or a stent procedure. If you are interested in getting more active and live in the Montreal area, this program may support your recovery.
Montreal, QuebecAges 65 years+ - NCT04016545Recruiting
Low-profile stent devices for elective TEVAR
This trial studies whether using newer, smaller “low-profile” devices during TEVAR can affect outcomes like complications and survival. If you need an elective TEVAR, this may help doctors compare safety and results with these newer tools.
Roma, RMAges Any age - NCT06208007Recruiting
Predicting heart failure with stiff arteries
This study looks at whether stiffer arteries can help predict a type of heart failure where the heart doesn't relax properly (HFpEF). It's for people who have risk factors like high blood pressure, diabetes, or being older, and who may have early signs of heart trouble.
Göttingen, Lower SaxonyAges 18 years+ - NCT06197724Recruiting
MCG test for chest pain patients scheduled for heart scans
This trial is testing a new magnetic heart scan (MCG) to see if it can better detect blockages in people with chest pain that is not a full heart attack. If you are having chest pain and are already scheduled for a heart catheterization or CT scan, this study might help find the cause more accurately.
Jinan, ShandongAges 18 years+ - NCT07295769Recruiting
Detecting hidden atrial fibrillation after stroke of unknown cause
This study uses a small patch (M.E.M.O. Patch) to continuously monitor your heart rhythm for hidden atrial fibrillation, a treatable cause of stroke. The goal is to see if the patch can find irregular heartbeats that standard tests might miss.
Seoul, Songpa-guAges 19 years+ - NCT07212803RecruitingPhase 4
Energy drinks study for young healthy adults
This study looks at how energy drinks affect your heart. It compares the effects of two different energy drinks on heart rate and other heart measures. You will have several short visits where you drink an energy drink and get your heart checked.
Stockton, CaliforniaAges 18–40 - NCT07478887Recruiting
Corrie Lipids app for better cholesterol management
This study tests a smartphone app called Corrie Lipids to help people with high cholesterol get their LDL levels under control. It may be a good fit if you have high cholesterol that isn't well managed and you have heart disease risk factors like diabetes or a family history.
Baltimore, MarylandAges 18 years+ - NCT06182397Recruiting
Drug-coated balloon for leg artery blockages below the knee
This trial tests a special balloon coated with sirolimus (a drug that helps prevent arteries from re-closing) versus a standard balloon for opening blocked arteries below the knee in people with severe leg pain or foot wounds. The goal is to see if the drug-coated balloon works better to keep the artery open longer.
Scottsdale, ArizonaAges 21 years+ - NCT06172842Recruiting
Heart ultrasound study for electrical rhythm problems
This study uses special ultrasound techniques to look at how the heart works in people who have heart rhythm problems caused by electrical issues, not structural ones. It aims to better understand and treat these conditions.
GuangzhouAges Any age - NCT05874479Recruiting
Lower air pollution exposure to help lower blood pressure
This study tests whether reducing air pollution exposure can lower blood pressure in adults with high blood pressure living in New York City public housing. You may be asked to follow steps to reduce exposure and complete monitoring during the study period.
New York, New YorkAges 18–100 - NCT06175650Recruiting
Female-focused recovery plan after heart surgery
This study looks at how to improve recovery after heart surgery, especially for women. It reviews medical records from people who had heart surgery in the past or will have it in the next few years at two hospitals in Amsterdam.
Amsterdam, North HollandAges 18 years+ - NCT06169540Recruiting
Saliva test for heart failure diagnosis
This study tests whether a simple saliva sample can detect certain molecules (lncRNAs) that might help diagnose heart failure. It looks at two types of heart failure: chronic stable heart failure and acute decompensated heart failure, and compares them to people without heart failure who are having a heart procedure.
Boston, MassachusettsAges 18 years+ - NCT06171061RecruitingPhase 4
Yangxinshi tablets for better exercise in heart disease
This study tests if Yangxinshi tablets can help people with chronic coronary syndrome (a type of heart disease) walk farther or exercise longer. It's for those whose heart condition limits their daily activity.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07003386RecruitingPhase 2/Phase 3
Galantamine for recent ischemic stroke
This trial tests a plant-based medicine called galantamine, given within 3 days of an ischemic stroke, to see if it helps recovery. It combines Western and Traditional Chinese Medicine approaches and aims to understand how the treatment works.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07725185Enrolling by invitation
Can remimazolam protect heart health during surgery?
This study tests whether a sedative called remimazolam can help protect the heart during surgery in older adults. If you are 65 or older and having a longer surgery with general anesthesia, this trial may be for you.
Jiaxing, ZhejiangAges 65 years+ - NCT06165081Recruiting
Emergency care after cardiac arrest and short-term outcomes
This study looks at how care in the emergency room after a cardiac arrest affects short-term recovery. It may help doctors find better ways to treat patients whose hearts have stopped outside the hospital.
Hsinchu, Hsinchu CityAges 20 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.