Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT05848622Recruiting
Gait retraining after ACL surgery for fast knee recovery
This trial tests a walking (gait) rehabilitation program to improve how you move after ACL reconstruction. It may help if you are still having walking mechanics issues in the months to years after surgery.
Chapel Hill, North CarolinaAges 16–35 - NCT05877014RecruitingPhase 3
Compare two fixation methods for adult arm shaft fractures
This trial tests whether one surgical technique (for stabilizing the upper-arm bone using a rod placed inside the bone) works better than another for adult humeral shaft fractures. It may help find the approach that leads to better healing and recovery.
DijonAges 18 years+ - NCT05863754Recruiting
Networked device that helps assess hand muscle movement
This trial tests a networked neuroprosthesis device designed to interact with nerves in the arm/hand to help assess grasp and release movements. It may help people with certain long-term spinal cord injuries regain more controlled hand function and researchers measure how well the system works.
Cleveland, OhioAges 16 years+ - NCT05848778Enrolling by invitation
Noninvasive treatment aimed at nerve regrowth in the hand
This trial tests a non-surgical therapy to help regrow damaged hand nerves and improve symptoms like numbness, pain, and hand weakness. It may be most helpful if your nerve damage affects sleep and hand dexterity.
Edmonton, AlbertaAges 18–60 - NCT05851898RecruitingPhase 4
Tested medicine to prevent depression after hip or leg fractures
This trial studies whether a type of antidepressant medicine (a serotonin–norepinephrine reuptake inhibitor) can prevent depression after a lower-extremity fragility fracture that was treated with surgery. It’s mainly for older adults, and aims to see if starting this medicine early reduces later depression symptoms.
Winston-Salem, North CarolinaAges 65 years+ - NCT05866029Recruiting
Prevention and treatment study for new brittle bone fractures
This study looks at ways to prevent and treat “brittle bone” refractures after a recent fracture in people with osteoporosis. If you’ve had a new hip, spine, or other bone fracture, the trial may test strategies to lower the chance of another fracture.
BeijingAges 45–90 - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT05820893RecruitingPhase 2
Resistant potato starch for Gulf War gut and fatigue
This Phase 2 study tests whether resistant potato starch can improve Gulf War illness (GWI), especially gut symptoms and fatigue, in older adults. You may be asked to follow a study plan and provide stool samples, while avoiding certain medications and recent infections.
Madison, WisconsinAges 50–85 - NCT05818241Recruiting
Recovery and satisfaction after a wrist bone fracture
This trial studies how satisfied patients are with recovery after a specific type of wrist fracture (distal radius) and how well recovery goes. It may help improve care and rehabilitation for people healing from this injury.
Mölndal, Region Västra GötalandAges 18 years+ - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
San Francisco, CaliforniaAges 18–65 - NCT05825027Recruiting
Sorting out risk in children with a recent concussion
This study looks at how to identify which children are at higher risk after a concussion and how they should be monitored. It may help doctors choose safer, more personalized follow-up care after a recent head injury.
Durham, North CarolinaAges 11–17 - NCT05843786RecruitingPhase 3
Interferon gamma for ventilator pneumonia in ICU
This trial tests whether a medicine called interferon gamma can improve outcomes in adults with a first episode of pneumonia that develops after being on a ventilator in the ICU. It is designed for specific ICU timing, infection severity, and immune marker levels, and it compares treatment on top of standard care.
LimogesAges 18 years+ - NCT05822466Recruiting
Virtual Tai Chi program to help prevent falls
This study tests whether a virtual (online) Tai Chi–style exercise program can reduce falls in older adults. You may be eligible if you’ve fallen recently or have a mobility test result that suggests a higher fall risk.
Springfield, OregonAges 65–90 - NCT05821517RecruitingPhase 4
Breathing or virtual reality to treat shoulder dislocation pain
This trial compares two ways to help control pain after an anterior (front) shoulder dislocation: methoxyflurane breathing and a virtual reality headset, versus usual pain treatment. It may help some people by making pain control easier during treatment.
NiceAges 18 years+ - NCT05837286Recruiting
Conservative care for trigger finger after steroid shots
This study looks at non-surgical (conservative) treatment options for trigger finger after you’ve already had a cortisone shot in the affected finger(s). It may help determine what approach works best to reduce symptoms without more invasive procedures.
Los Angeles, CaliforniaAges 18–100 - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05785182Recruiting
Scans with eye imaging for open and infected broken bones
This trial studies a special scan technique (using light from an eye camera) to look at healing in open fractures that are infected. It may help doctors better monitor how these difficult injuries respond to treatment.
Lebanon, New HampshireAges 18 years+ - NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT05805683Recruiting
Calcitonin for nerve pain after spinal cord injury
This study tests whether calcitonin can prevent or lessen nerve pain after a spinal cord injury. It may help reduce how often neuropathic (nerve-type) pain happens and how severe it becomes.
Tanta, Gharbia GovernorateAges 18 years+ - NCT05792189Recruiting
Knee fracture surgery: plates vs knee replacement for older adults
This trial compares two ways to treat certain lower-thigh (distal femur) fractures near the knee: using plates/screws or doing a knee replacement. It aims to see which option works better for recovery and long-term outcomes.
Gainesville, FloridaAges 55–100 - NCT05794165Enrolling by invitationPhase 2
Antithrombin to prevent blood clots after serious trauma
This Phase 2 trial studies whether giving antithrombin can better prevent harmful blood clots (venous thromboembolism) after serious injuries. The goal is to reduce clot risk while you’re in the trauma ICU or step-down unit.
Aurora, ColoradoAges 18 years+
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.