Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT05783245Recruiting
Cooling therapy to reduce pain after open carpal tunnel surgery
This trial studies whether cooling (cold therapy) can lessen pain after open carpal tunnel release surgery. If you’re having this surgery, your answers to questionnaires and your current pain-medication status will determine whether you can join.
Chicago, IllinoisAges 18 years+ - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05786313Recruiting
Open-door neck surgery plan for cervical spinal narrowing
This study looks at a more tailored and standardized surgical approach for people with neck spinal narrowing and spinal cord symptoms. It may help doctors compare and improve how well surgery works for different patients.
Xi'an, Shannxi ProvinceAges 28–85 - NCT05805774Recruiting
Compare fixing versus replacing a fractured thigh bone
This study looks at the best surgical option for an acute (new) fracture of the lower thigh bone near a stable knee replacement. It compares surgery that “fixes” the bone versus surgery that “replaces” part of the bone to help you walk again safely.
Toronto, OntarioAges 65 years+ - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05317390Recruiting
Tests an AI tool to diagnose isolated dystonia
This trial checks whether an AI (software) called DystoniaNet can accurately identify isolated dystonia using information from your evaluation, and compares its results to standard diagnosis. If you have focal, segmental, or generalized dystonia, this study may help improve faster and more accurate diagnosis in the future.
Boston, MassachusettsAges Any age - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT05776030Recruiting
Test of different-speed ergonomic wheelchairs for daily users
This study tests a wheelchair design that can better match how you move and sit while using a manual wheelchair every day. You may be able to try different wheelchair setups if you meet the safety, seating, and body-size requirements.
Minneapolis, MinnesotaAges 18 years+ - NCT05752695Enrolling by invitation
Rehab program for athletes with an ACL injury
This study looks at a rehab program (“Operation Korsband”) for athletes who have an ACL injury. It may help improve recovery and return to sport.
KalmarAges 12–55 - NCT05768802Recruiting
Testing a forearm implant that records muscle signals for prosthetic use
This study tests a small implant that records signals from your forearm muscles in people with a specific type of arm amputation. It aims to help improve how well prosthetic hands can be controlled using muscle activity.
Pittsburgh, PennsylvaniaAges 22–70 - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05769114Recruiting
Surgery vs non-surgery for a specific back fracture
This study compares surgery and non-surgical care for an acute burst fracture in the middle-to-lower back. The goal is to see which approach works better for healing and recovery.
BernAges 18–70 - NCT05766670RecruitingPhase 3
Calcium and antibiotic placed inside tibia nail for open fractures
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05772468Enrolling by invitation
Virtual pain care for people getting wound treatment
This trial tests a virtual (VR) pain-care approach during wound care procedures. It may help reduce how painful the treatments feel, especially for people who have had very painful wound care before.
Amsterdam, North HollandAges 18 years+ - NCT05732870Recruiting
Study looks for blood and gene signals that affect bone health
This study collects information and samples around the time of certain bone or joint surgeries (like joint replacement or fracture repair) to learn what factors help or harm bone healing. The results may help find better targets to improve long-term bone health and recovery.
London, Greater LondonAges 18–110 - NCT05744024Enrolling by invitation
VR-based comfort care during complex wound procedures
This trial studies a non-medicine way to reduce pain during complex wound care, possibly using VR or similar distraction tools. You may be able to join if you have painful wound procedures and can safely use the VR setup.
Amsterdam, North HollandAges 18 years+ - NCT05723614Recruiting
Housing help to reduce exposure to violence in New Haven
This study offers housing-related assistance to help families affected by incarceration live more safely in high-violence neighborhoods. It looks at whether this support reduces how much violence people are exposed to.
New Haven, ConnecticutAges Any age - NCT05713630RecruitingPhase 3
Tranexamic acid for symptomatic subdural blood clots
This trial studies whether tranexamic acid (a medicine that helps slow blood breakdown) can improve outcomes for people with symptomatic subdural hematoma—blood collecting between the brain and its outer covering. You may be able to join if you’re older, have bleeding seen on CT, symptoms linked to the bleed, and meet several safety and timing rules.
Toronto, OntarioAges 45 years+ - NCT05719844Recruiting
Computer tests to assess concussion recovery in young rugby players
This study checks whether a set of computer-based attention and thinking tests can help manage concussion (a brain injury) in young rugby players. It compares players who had a concussion with similarly aged players who haven’t had one.
Clermont-FerrandAges 11–25 - NCT05714293Enrolling by invitation
CT measurements after surgical aortic valve replacement
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
RomaAges 18–80 - NCT05741788Recruiting
Telefitting spinal cord stimulation for chronic pain
This study checks a “remote fitting” process to set up spinal cord stimulation for people with high levels of pain. You may be a fit if you are planning a stimulation trial and have severe pain right now.
Minneapolis, MinnesotaAges 22 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT05742776Recruiting
Ultrasound and sleep quality check in carpal tunnel
This trial studies whether ultrasound exam findings match how well you sleep if you have carpal tunnel syndrome. It may help doctors better understand which ultrasound results go along with worse sleep and symptoms.
Afyonkarahisar, Afyonkarahi̇sarAges 20–80
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.