Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT03858231RecruitingPhase 4
Opioid vs non-opioid pain relief after knee arthroscopy
This study compares opioid pain medicine with non-opioid pain medicine after arthroscopic (keyhole) knee surgery. It aims to see which approach controls pain well while keeping side effects and risks lower.
Fargo, North DakotaAges 18–80 - NCT03741023Enrolling by invitation
Blood tests after trauma or surgery to study body stress response
This study looks at how your body’s inflammation and “stress response” changes after major injury or certain surgeries. Doctors may use the results to better understand who is at risk for complications and how to respond sooner.
Nashville, TennesseeAges 2 months+ - NCT03790943Recruiting
Health study of heart problems in childhood cancer survivors
This study follows people who had cancer as children to learn about heart-related changes years after treatment. It may help doctors better understand who is at risk and how to monitor the heart in long-term survivors.
Basel, Canton of Basel-CityAges 18 years+ - NCT03803787RecruitingPhase 2
Inhaled steroid to prevent lung inflammation during cancer treatment
This trial tests whether breathing in steroid medicine before and during radiation can lower how often and how badly “radiation lung inflammation” (radiation pneumonitis) happens in people with lung cancer. If you qualify, it may help protect your lungs while you receive radiation with chemotherapy or targeted therapy.
Mexico CityAges 18–75 - NCT03765567RecruitingPhase 4
Antibiotic powder placed in certain emergency open fractures
This study tests whether putting antibiotic powder directly into an open fracture wound in the emergency room can improve care outcomes. It focuses on adults treated shortly after injury.
San Antonio, TexasAges 18–89 - NCT03796572RecruitingPhase 4
Nerve-block pain relief after a specific elbow bone fracture
This trial studies whether a pain-relief “nerve block” with medicine helps control pain after surgery for a particular type of elbow (humerus) fracture. It may help you feel more comfortable during recovery, compared with standard pain control.
Los Angeles, CaliforniaAges 4–12 - NCT03867539RecruitingPhase 4
Numbing shot and education to reduce opioids after carpal tunnel surgery
This study tests whether giving a long-lasting numbing injection (Exparel) plus education about pain management can help people avoid taking opioid pain pills after carpal tunnel release surgery. It may help reduce opioid use while still supporting comfort during recovery.
Dayton, OhioAges 18 years+ - NCT03857945Recruiting
Training to prevent falls after foot or ankle surgery
This trial studies whether teaching people to use mobility devices before surgery can lower the chance of falling afterward. It’s for adults having planned (elective) one-sided foot or ankle surgery and who will need limited walking after surgery.
Birmingham, AlabamaAges 18 years+ - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT03617562Recruiting
Compare two surgeries for large rotator cuff tears
This trial compares two different operations to treat large, hard-to-repair rotator cuff tears. If your tear is too damaged to be repaired in the usual way, the study tests whether one surgical approach may work better than a partial repair.
Toronto, OntarioAges 18–65 - NCT03680872Recruiting
Brain-to-nerve study to improve hand movement after spinal injury
This trial tests a “neural bypass” approach to help restore hand movement and feeling in people with tetraplegia from a spinal cord injury. You would have repeated visits for brain/nerve testing and may receive study procedures to see if function improves.
Manhasset, New YorkAges 22–65 - NCT03652753RecruitingPhase 4
NAC injection during staged surgery for pilon fractures
This study looks at whether injecting N-acetylcysteine (NAC) into the joint during staged surgery can improve care for certain high-energy pilon fractures. It may help support healing where the joint is involved.
Columbia, MissouriAges 18 years+ - NCT03561376RecruitingEarly Phase 1
Zinc ointment versus petroleum jelly after skin surgery
This early-phase trial compares zinc oxide ointment versus petroleum jelly to help healing and scar appearance after certain skin surgeries. You might be able to join if you are having a suitable, uninfected, non-scalp skin incision and can use the study ointment.
Pittsburgh, PA, PennsylvaniaAges 18 years+ - NCT03696199RecruitingPhase 4
Test better pain control after ankle fracture surgery
This trial studies a pain-control approach (a kind of nerve block) to see if it can reduce pain after surgery for certain ankle fractures. It may help you feel more comfortable while your ankle heals after an operation.
Burlington, MassachusettsAges 18–89 - NCT03695887RecruitingEarly Phase 1
Disposable nitrous oxide for pain during burn dressing changes
This early-stage study tests whether using disposable nitrous oxide canisters can better control pain when you need burn dressing changes. It may help by making dressing changes more comfortable, but eligibility depends on your burn size, health, and breathing ability.
Winnipeg, ManitobaAges 18 years+ - NCT03713853Recruiting
Compare hip surgery methods for new pelvic bone fractures
This study compares two ways of fixing a recently broken acetabulum (the hip socket): one method keeps/repairs the socket (ORIF) and the other replaces it (THA). It aims to find which surgery approach leads to better outcomes for people who can have surgery soon after the injury.
Toronto, OntarioAges 60 years+ - NCT03698149Recruiting
Brain-signal training for hand and speech control after disability
This study tests whether recording brain signals can help people regain better control of movements in the arms and help with speech. It may be an option for people with significant disability from certain nerve and brain conditions who can safely take part in brain-monitoring procedures.
San Francisco, CaliforniaAges 21 years+ - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT02225301Recruiting
Online training for childcare staff to spot child abuse
This study tests an online learning program (“module”) for people who work in childcare. It aims to help early childcare providers recognize signs of possible child abuse and respond appropriately.
Hershey, PennsylvaniaAges 18 years+ - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT03441659Recruiting
ACL reconstruction recovery study using clinical outcome tracking
This study looks at outcomes after surgery to repair the ACL (a knee ligament that helps stabilize the joint). If you’re having ACL reconstruction, the trial may help doctors understand what factors lead to better recovery.
Bologna, ItaliaAges 18–60 - NCT03400345Recruiting
Follow-up for transplanted arm patients
This study follows people who received a transplanted arm (or both arms) to learn from their ongoing care. You may be asked for small tissue samples (biopsies) and to continue an immunotherapy plan to help protect the transplant.
Baltimore, MarylandAges 18–100 - NCT03368092RecruitingPhase 3
Inhaled medication to prevent lung failure after severe trauma
This trial tests whether inhaled dornase alfa can reduce the risk of respiratory (lung) failure in adults with severe trauma who are on a breathing machine in the ICU. If it works, it may help patients spend less time with dangerous breathing complications.
StrasbourgAges 18 years+
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.