Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07449806Recruiting
Comparing two bone graft materials for front tooth implants
This trial looks at two different types of bone graft material used when placing a dental implant right after removing a front tooth. It aims to see which one better maintains the thickness of the bone on the lip side of the implant.
AlexandriaAges Any age - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT07452640Recruiting
Comparing two non-surgical gum treatments for advanced periodontitis
This study compares two methods for treating advanced gum disease (periodontitis) without surgery: one uses a special ultrasound device (Vector® system) and the other uses small hand tools (Mini-Five curettes). The goal is to see which cleans deeper pockets better and helps gums heal.
AnkaraAges 18–65 - NCT07453147Recruiting
Gum graft surgery for multiple teeth with recession
This study compares two ways of doing a gum graft surgery to cover exposed tooth roots. It may help patients who have gum recession on multiple teeth and want a less invasive treatment.
Liège, LiègeAges 18 years+ - NCT07455656Recruiting
Vitamin D3 or gum massage for faster canine movement with braces
This study tests whether applying vitamin D3 or a special gum massage (corticision) next to the teeth can help move your eye teeth (canines) faster after your upper first premolars are removed for braces. It is for teenagers or young adults who already need that extraction as part of their orthodontic plan.
Cairo, Cairo GovernorateAges 13–20 - NCT07459049RecruitingPhase 4
Ibuprofen for gum inflammation after deep cleaning
This trial tests whether ibuprofen can help calm gum inflammation after a deep cleaning for periodontitis. It is for adults with moderate-to-severe gum disease who are otherwise healthy.
BaghdadAges 18 years+ - NCT07459296RecruitingPhase 3
Becotatug vedotin plus sintilimab for advanced nasopharyngeal cancer
This trial tests a combination of two drugs, becotatug vedotin and sintilimab, for patients with a type of nasopharyngeal cancer that has spread to nearby lymph nodes but not to distant organs. It aims to see if this treatment can help control the disease.
Nanning, GuangxiAges 18–70 - NCT07460076Recruiting
Immediate tooth implant with bone graft from the upper jaw
This trial tests placing a dental implant right after removing a tooth, using a small piece of bone from the back of your upper jaw to rebuild the gum area. It may help people who need a front tooth replaced and have a bone defect that requires this type of graft.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07463859Recruiting
Treating gum disease and bad breath in diabetes patients
This trial tests whether combining standard gum treatment with a light-activated therapy can reduce bad breath in people with type 2 diabetes and advanced gum disease.
Bauru, São PauloAges 18–70 - NCT07464197Recruiting
Tooth whitening with custom 3D-printed trays
This study tests if 3D-printed whitening trays work as well as regular custom trays. You'll use a whitening gel at home for a short time to see how white your teeth get.
Sant Cugat del Vallès, BARCELONAAges 18 years+ - NCT07465978Recruiting
Testing printed hybrid resin for dental overlays
This trial tests a special printed material used for tooth overlays (caps that cover the entire top of a back tooth). If you need a full overlay on a molar that has had root canal treatment, this study may be a good fit.
Sant Cugat del Vallès, BarcelonaAges 18 years+ - NCT07466641Recruiting
Low-level laser or Piezocision to speed up canine tooth movement
This trial compares two treatments to see if they can safely speed up a specific tooth movement during braces. It tests a low-level laser or a minor surgical procedure called Piezocision against standard care.
Cairo, Cairo GovernorateAges 18–25 - NCT07466966Recruiting
Non-surgical treatment for implant infection
This study tests a less invasive way to treat peri-implantitis (infection around a dental implant) without removing the implant crown or using antibiotics. It may help people with infected implants who have not smoked or used antibiotics recently.
BrnoAges 18 years+ - NCT07471386Recruiting
Gum graft for implant infection
This trial tests whether adding gum tissue around a dental implant helps treat an infection around the implant. It may be a good fit if you have a dental implant with inflammation and very little attached gum.
AnkaraAges 18–75 - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT07479290RecruitingPhase 1
Vitamin D gel to speed up tooth movement after extraction
This trial tests whether applying vitamin D near the extraction site can speed up how quickly your canine teeth move into the gap after premolars are removed. It might help shorten your orthodontic treatment.
Islamabad, FederalAges 13 years+ - NCT07483086Recruiting
Implant position for thin gum patients
This study tests whether the vertical position of a dental implant affects bone loss around it, specifically for people with thin gums. If you are missing a single upper front tooth or premolar, you may be a candidate.
CairoAges 18 years+ - NCT07484685Recruiting
Earlier implant placement after tooth preservation
This study tests if placing a dental implant sooner (about 6-8 weeks after tooth removal and socket preservation) works well with a specific implant type. It is for people who need to replace a single front tooth, canine, or premolar and have good bone and gum health.
Guayaquil, GuayasAges 18 years+ - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT07167771Recruiting
Saliva markers for gum disease: a follow-up study
This study follows up with people who already took part in a previous saliva and gum health study. Researchers want to see if certain substances in saliva can predict gum disease progression over time.
MadridAges 18 years+ - NCT07672873Recruiting
Steroid injection for tooth nerve pain during root canal
This trial tests whether a single injection of dexamethasone (a steroid) near the nerve of a painful lower molar can improve pain relief during a root canal. It's for people with severe tooth nerve pain who haven't taken pain meds recently.
IstanbulAges 18–65 - NCT07493941Enrolling by invitation
Bleaching teeth with different light methods
This study compares different ways of activating a teeth-whitening gel to see which works best, feels best, and causes the least tooth pain. If you want whiter teeth and are in good oral health, this may be for you.
Tanta, TantaAges 20–35 - NCT06648564Enrolling by invitation
20-25 Year Follow-Up on Bone Grafts for Gum Disease Around Implants
This study follows up on patients who had a bone graft procedure to treat gum disease around dental implants 20 to 25 years ago. It aims to see how well the treatment worked over the long term.
KristianstadAges Any age - NCT07487272Recruiting
Cell mapping in gum disease tissues
This study looks at the cells in gum tissue from people with different types of periodontitis (aggressive or chronic) and healthy gums. By understanding which cells are active and how they interact, researchers hope to find better ways to diagnose or treat gum disease.
Hangzhou, ZhejiangAges 20–40
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.