Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07361809Recruiting
Desvenlafaxine for shingles pain relief
This trial tests if desvenlafaxine (an antidepressant also used for nerve pain) can safely reduce pain from shingles. It may be an option if your shingles pain is moderate to severe and started within the last 3 months.
BeijingAges 18 years+ - NCT07363395RecruitingPhase 1
A study of ASCT-83 in healthy adults
This trial tests a new medication called ASCT-83 in healthy adults to see how safe it is and how the body processes it. It may help researchers understand the right dose for future studies.
Saint Paul, MinnesotaAges 18–64 - NCT07365566Recruiting
Pain and sleep behavior disorder study
This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.
ToulouseAges 18 years+ - NCT07366684Recruiting
Heart attack study for adults 75 and older
This study looks at how frailty and other health factors affect recovery in people 75 and older who have had a heart attack or unstable chest pain. It may help doctors better understand who is at higher risk and how to improve care for older adults.
NišAges 75 years+ - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07370389Recruiting
Testing a new pain drug for shingles pain
This trial tests a new pain medication called tulodesvenlafaxine for people with shingles-related pain. It may help if you have moderate to severe pain that started within the last 90 days.
BeijingAges 18 years+ - NCT07370402Recruiting
Flurbiprofen patch for shingles pain relief
This trial tests if a flurbiprofen skin patch can reduce pain from shingles (herpes zoster). It may help people with moderate to severe pain who have had the rash for less than 90 days.
BeijingAges 18 years+ - NCT07370428Recruiting
Numbing injection for pain relief after lower back surgery
This study tests whether an ultrasound-guided numbing injection near the hip area can provide better pain relief after lower back surgery. If you qualify, you may receive this injection to help control pain after your operation.
BursaAges 18–65 - NCT07370974Recruiting
Hypnosis for anxiety before abdominal surgery
This study tests if a short hypnosis session before abdominal surgery can help reduce anxiety. It may be an option if you are scheduled for such a surgery and have no major psychological conditions.
Kenitra, ProvinceAges 18–80 - NCT07372547Recruiting
Does Shower Standing Help Women Empty Bladder After Catheter Removal?
This trial compares standing in the shower versus sitting on a toilet to see which position helps women empty their bladder more completely after a urinary catheter is removed following vaginal surgery.
AshdodAges 18–99 - NCT07373808Recruiting
Nerve stimulation and exercise for sciatica leg pain
This study tests whether combining a mild electrical stimulation of the sciatic nerve with specific exercises can reduce leg pain from sciatica. It is for people whose nerve-related leg pain has lasted over 6 months and is at least a 3 out of 10 in intensity.
Madrid, MadridAges 18–70 - NCT07374354Recruiting
Pain and anxiety control for kids with MIH
This study tests a pain-relieving medicine given before dental treatment to see if it helps reduce pain and anxiety in children with molar incisor hypomineralization (MIH), a condition that causes weak enamel on molars and front teeth.
GizaAges 6–12 - NCT07375576Recruiting
Comparing partial nerve removal to root canal for severe tooth pain
This study compares two ways to treat severe tooth pain from advanced decay: a partial nerve removal (pulpotomy) versus a full root canal treatment. It aims to find which approach works better for saving the tooth.
Hatay, AntakyaAges 18–45 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07377370Recruiting
Pain after gum graft surgery study
This study looks at factors that affect pain after a gum graft procedure. If you need gum surgery to cover exposed tooth roots or add gum tissue, you may be able to join.
Barcelona, Sant Cugat Del VallesAges 18 years+ - NCT07378046Recruiting
Baclofen for shingles pain: a safety and effectiveness study
This study tests whether the muscle relaxant baclofen can safely reduce shingles pain. It is for adults with moderate to severe pain who have not tried this drug before.
BeijingAges 18 years+ - NCT07378059Recruiting
Loxoprofen patch for shingles pain
This trial tests if a loxoprofen skin patch (a non-steroidal anti-inflammatory drug) can safely relieve moderate to severe pain from shingles. It may be an option for people who have had shingles rash for less than 90 days.
BeijingAges 18 years+ - NCT07378865RecruitingPhase 1
How suzetrigine passes into breast milk
This study looks at how much of the study drug, suzetrigine, gets into breast milk. It helps us understand if it's safe for breastfeeding mothers and their infants.
Salt Lake City, UtahAges 18 years+ - NCT07378995Recruiting
Can play before a shot help children?
This study tests whether a fun, play-based activity given just before an antibiotic shot helps children feel less pain and fear. If your child is 4–6 years old and needs this specific shot, they may be eligible.
ErzurumAges 4–6 - NCT07380789Recruiting
Managing acute chest pain after battle injuries
This study is testing better ways to manage severe chest pain after combat injuries in Ukraine. If you have chest pain from battle and are 18 or older, it may help find a treatment that works for you.
RivneAges 18–60 - NCT07381621Recruiting
Comparing sugar water vs. numbing shots for knee arthritis
This study compares two different types of knee injections for people with knee osteoarthritis. One injection uses a simple sugar solution (dextrose), and the other uses a standard numbing medication (local anesthetic). The goal is to see which works better for reducing pain and improving knee function.
Ankara, AltindagAges 40–65 - NCT07382297Recruiting
Knee tumor pain study with extra nerve block
This study tests if adding an ultrasound-guided nerve block (IPACK) behind the knee to a standard nerve block (adductor canal block) can better control pain after knee tumor surgery. If you are having knee tumor removal and are in fair to poor health, this may help improve your recovery.
CairoAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.