Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07382973Recruiting
NTP safety in thyroid surgery: preventing complications
This trial is testing if a technology called NTP (a type of low-temperature plasma) can help prevent complications and improve cancer control when they remove all or part of the thyroid gland. It's for adults having thyroid surgery.
Ocoyoacac, State of MexicoAges 18 years+ - NCT07386353RecruitingPhase 4
Comparing two ways to give pain medicine after C-section
This trial tests two different ways of giving morphine for pain relief after a planned cesarean section: one is injected into the spinal fluid and the other into the space around the spinal cord. The goal is to see which method works better and is safer.
Funchal, MadeiraAges 18 years+ - NCT07386418Recruiting
Angina thresholds study for patients needing stent treatment
This trial is testing a new way to measure blood flow in the heart during exercise to better understand angina. You may be eligible if you have at least two blocked heart arteries and are scheduled for stent placement.
BasildonAges 18 years+ - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT07391930Recruiting
High intensity exercise for period pain
This study tests if high-intensity interval training (short bursts of intense exercise) can help reduce period pain. It is for people who have not given birth and experience regular period pain.
Alcalá de Henares, MadridAges 18–40 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07393672RecruitingPhase 2
Cannabinoids for menopause symptoms
This trial tests if hemp-derived cannabinoids can help with menopause symptoms like hot flashes and sleep issues. It may be an option if you are between 40 and 60, no longer having monthly periods or starting the transition, and can use a smartphone for virtual visits.
Pullman, WashingtonAges 40–60 - NCT07393958Recruiting
Can food supplements improve quality of life with endometriosis pain?
This study tests if a food supplement (Doliral®) can help reduce pelvic pain and improve daily life in women with endometriosis. It is for those with mild to moderate endometriosis (stages I–III) who have had pain for at least three months but do not need surgery right now.
BarcelonaAges 18 years+ - NCT07394673Recruiting
Nerve block for pain after shoulder surgery
This trial tests a new ultrasound-guided nerve block for pain relief after shoulder surgery. It aims to improve comfort and reduce the need for pain medications.
BursaAges 18–65 - NCT07395934Recruiting
Comparing two epidural methods for labor pain relief
This study compares two ways of giving epidural pain relief during labor: a programmed intermittent bolus (PIEB) versus a continuous infusion (CEI). The goal is to see which method works better for managing pain in vaginal delivery.
Da NangAges 18–40 - NCT07396545Recruiting
Comparing two types of nerve blocks for pain after stomach cancer surgery
This trial looks at two different pain-blocking injections (nerve blocks) to see which one works better for pain after keyhole stomach cancer surgery. If you are having this type of surgery, joining could help us learn which block gives you better pain relief.
Yinchuan, NingxiaAges 18 years+ - NCT07396753Recruiting
Nerve block to reduce opioid use after kidney donor surgery
This study tests a nerve block called Transversalis Fascia Plane Block to see if it lowers the amount of strong pain medicine (opioids) needed after a kidney donor surgery. It may help you have less pain and fewer side effects.
Istanbul, ZeytinburnuAges 18–80 - NCT07397117Recruiting
Ultrasound-guided nerve block for sciatica pain
This trial tests if an ultrasound-guided nerve block can provide better pain relief for sciatica compared to standard care. If you have severe leg pain from sciatica, this study might help you find effective pain control.
San Francisco, CaliforniaAges 18 years+ - NCT07397715Recruiting
Ultrasound signs of adenomyosis and related symptoms
This study uses ultrasound to look for signs of adenomyosis (a condition where the uterine lining grows into the muscle wall) and see how those signs relate to symptoms. It may help doctors better diagnose and treat the condition.
SosnowiecAges 18 years+ - NCT00389142Recruiting
Find genes linked to bladder pain and urinary symptoms
This study looks for genetic (inherited) causes of bladder pain syndrome (IC/BPS), using information from people who have typical urinary symptoms. It may help doctors understand why IC/BPS happens, which could guide better future care.
Boston, MassachusettsAges 1 year+ - NCT00499317Recruiting
Genetic study of chronic pelvic pain and bladder symptoms
This study looks for genetic (inherited) factors behind chronic pelvic pain and related urinary and sexual symptoms. You may be able to help researchers by providing a few samples and answering short questions, which could improve understanding of these conditions.
Boston, MassachusettsAges Any age - NCT00823563Recruiting
Testing heart artery causes of pain without major blockage
This study looks at people who are being checked for possible heart artery–related chest or similar discomfort, but without major artery blockage (non-obstructive arteries). It aims to help doctors understand what might be causing symptoms and guide safer testing.
Stanford, CaliforniaAges 18 years+ - NCT01838148Recruiting
Tests heart signals to detect reduced blood flow during exercise
This study looks at specific blood-flow and heart-rhythm signals during an exercise test to find signs of reduced blood flow to the heart. It may help doctors spot heart problems sooner and decide who needs more care.
BaselAges 18 years+ - NCT01566175Recruiting
Neovasc device trial for hard-to-treat chest pain
This trial tests a device called the Neovasc Coronary Sinus Reducer to help people with long-lasting, hard-to-control chest pain (angina) who cannot have artery-opening procedures. It may improve symptoms by changing blood flow in the heart’s vein system.
Tel AvivAges 18 years+ - NCT01788410Recruiting
MRI-guided freezing treatment for neck, head, and spine pain
This trial studies an MRI-guided procedure that “freezes” targeted nerves or joints to reduce pain in the head, neck, or spine. It may help if your pain comes from a joint problem or a compressed/damaged nerve and you can safely have MRI scans before and after the treatment.
Boston, MassachusettsAges 18 years+ - NCT00515060Recruiting
Study pain testing in cancer patients and healthy volunteers
This trial uses controlled, short-term pain testing (a “pain study”) to better understand how pain works during and after certain cancer treatments. It may help researchers improve how cancer therapy pain is measured and managed.
Houston, TexasAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.