Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07653490Recruiting
Two anesthesia methods for gallbladder surgery
This study tests whether a numbing injection in the back (erector spinae plane block) helps reduce anesthesia needs during gallbladder surgery. It compares two anesthesia methods to see which works better for pain control and recovery.
IstanbulAges 18–65 - NCT07655271Recruiting
Pain, arm function, and anxiety after shoulder surgery for brachial plexus palsy
This study examines pain, arm function, and social appearance anxiety in adults who had shoulder tendon transfer surgery as children for brachial plexus birth palsy. It helps understand long-term outcomes after this specific surgery.
Istanbul, IstanbulAges 18–40 - NCT07655323Recruiting
RISS vs. ESP Block for Gallbladder Surgery Pain
This study compares two types of nerve blocks (RISS and ESP) to manage pain after gallbladder removal surgery. It aims to find which block provides better pain relief.
Bursa, NilüferAges 18–75 - NCT07655336Recruiting
Nerve block comparisons for lung-sparing chest surgery
This trial compares two types of nerve blocks to manage pain during and after a type of lung surgery that removes only part of the lung. It aims to find which block provides better pain relief and recovery.
Bursa, NilüferAges 18–75 - NCT07657390RecruitingPhase 1/Phase 2
Acupoint plaster for moderate to severe cancer pain
This study tests a special pain-relief plaster placed on acupoints (body points used in acupuncture) to see if it can help people with moderate to severe cancer pain who are already taking pain medications. The goal is to find a gentler way to improve pain control.
BeijingAges 18 years+ - NCT07657845Recruiting
Long-term safety of a freezing nerve block before pectus surgery
This study checks the long-term safety of a procedure called cryoneurolysis, which uses cold to temporarily numb certain nerves before surgery to fix a sunken chest (pectus excavatum). It may be for people who already had this treatment.
Bergamo, BGAges 14 years+ - NCT07659990Recruiting
Comparing two nerve blocks for mastectomy pain relief
This study compares two types of nerve blocks given before a mastectomy (breast removal surgery) to see which one provides better pain relief. If you are having a mastectomy on one side with lymph node removal, you may be able to join.
Bursa, NilüferAges 18–75 - NCT07662733Recruiting
Acupuncture for better sleep and less pain after lung cancer surgery
This trial tests if acupuncture given before and after surgery can help patients sleep better and have less chronic pain after a lung cancer operation. You may join if you are having a specific type of lung cancer surgery, are in good general health, and do not have severe sleep problems already.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07665593Recruiting
AI breathing training after open heart surgery
This trial tests if an AI-assisted breathing exercise device can reduce pain, fatigue, and improve breathing in patients recovering from open heart surgery.
Kocaeli, İzmitAges 18 years+ - NCT07672145Recruiting
Gallbladder removal: belly button vs. upper belly cut
This trial compares two ways to remove the gallbladder during laparoscopic surgery: through the belly button or through a cut just below the breastbone. It aims to find which method causes less pain and recovers faster.
Lahore, Punjab ProvinceAges 18–60 - NCT07665086Enrolling by invitation
Isometric exercise for rheumatoid arthritis
This study tests whether simple isometric (holding still) exercises can help people with rheumatoid arthritis. The goal is to see if these exercises improve hand function and quality of life.
DenizliAges 18–65 - NCT07663604Enrolling by invitation
Pain experience in fibromyalgia
This study looks at how women with fibromyalgia experience pain. It aims to better understand their pain to help improve care.
Denizli, ŞirnakAges 18 years+ - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT07654192Enrolling by invitation
ShotBlocker and finger puppet for blood draw pain
This study tests two simple distraction methods—a small plastic device called ShotBlocker and a finger puppet—to see if they help reduce pain and fear during blood draws in children. It may help your child feel more comfortable and less scared.
BoluAges 5–10 - NCT07637552Enrolling by invitation
Deep vs. Shallow Needle Treatment for Neck Pain
This study compares two ways of using dry needling (a technique where thin needles are inserted into tight muscles) to treat neck pain caused by muscle knots. Researchers will use ultrasound and electrical testing to see which approach works better and is safer.
Dammam, Eastern ProvinceAges 18–65 - NCT07632729Enrolling by invitation
Knowledge of Results Training for Shoulder Pain
This study tests whether giving you immediate feedback during shoulder exercises helps reduce rotator cuff-related shoulder pain. The rotator cuff is a group of muscles and tendons in your shoulder; this trial focuses on people with impingement, bursitis, tendon inflammation, or small tears.
Ankara, SıhhıyeAges 18–35 - NCT07627425Enrolling by invitation
Staples vs. Sutures for Hernia Repair Mesh
This trial compares two methods of attaching mesh during hernia surgery—staples versus sutures—to see which leads to better healing and fewer problems after surgery. You'd have a 50/50 chance of receiving either method.
KarachiAges 18–75 - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07615595Enrolling by invitationPhase 4
Dexamethasone to reduce side effects from spinal anesthesia during cesarean delivery
This study tests whether giving a steroid medication (dexamethasone) before spinal anesthesia can reduce uncomfortable side effects like nausea, vomiting, and low blood pressure during planned cesarean delivery. The goal is to help you feel better during and after your surgery.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07610044Enrolling by invitation
Pelvic Floor vs. Swiss Ball Exercises for Chronic Low Back Pain
This study tests two exercise approaches—pelvic floor exercises and Swiss ball exercises—to see which better reduces long-term lower back pain in women. Both aim to strengthen core muscles that support your spine.
Lahore, Punjab ProvinceAges 18–35 - NCT07578181Enrolling by invitation
Aromatherapy Massage for Chronic Lower Back Pain
This study tests whether massage combined with essential oils (lavender, orange, and almond oil) can help reduce chronic lower back pain that has lasted at least 6 months. Researchers want to see if aromatherapy massage is a safe and helpful treatment option.
Kırşehir, MerkezAges 18–65 - NCT07578168Enrolling by invitation
Kinesio Tape for Rotator Cuff Shoulder Pain
This study tests whether kinesiology tape (a special stretchy tape applied to the skin) can reduce pain and improve function in people with rotator cuff syndrome, a common shoulder condition. You'll be randomly assigned to receive the tape or a control treatment and tracked over several weeks.
Kırşehir, MerkezAges 18–65 - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07568405Enrolling by invitation
How Remifentanil Affects Pain Sensitivity During Surgery
This study tests how a pain-relief medication called remifentanil changes the way your body responds to pressure pain. Researchers will measure your pain sensitivity before and after receiving this medication to better understand how it works.
Brussels, Brussels CapitalAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.