Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07562737Enrolling by invitation
Neck Pain Management for Office Workers
This study looks at ways to help office workers who spend long hours at a desk manage or prevent neck pain. Researchers want to understand what works best for people whose neck pain comes from sitting and working, not from a specific injury or condition.
Kaunas, Lt-44221Ages 18–65 - NCT07561489Enrolling by invitation
Study of OsteoPearl Implants for Spine Fractures
This study observes how a biological implant called OsteoPearl helps people recover from recent spine fractures in the mid or lower back. Researchers will track your pain relief and ability to function over time after a minimally invasive procedure to stabilize the fracture.
Williamsville, New YorkAges 50 years+ - NCT07553533Enrolling by invitation
Temporary Nerve Stimulation for Headache Relief
This trial studies a temporary nerve-stimulation device placed near the back of your head to treat chronic headaches. The device sends mild electrical pulses to help reduce headache pain over 60 days, and your doctor has already decided this treatment is right for you as part of your regular care.
New Haven, ConnecticutAges 18 years+ - NCT07549685Enrolling by invitation
Music Therapy to Help Breast Cancer Patients During Chemotherapy
This study tests whether music therapy can help women with breast cancer feel better during chemotherapy after surgery. Researchers will see if listening to or participating in music sessions improves quality of life and reduces stress during treatment.
AlessandriaAges 25–75 - NCT07545850Enrolling by invitation
Virtual Reality Glasses to Reduce Pain During IUD Insertion
This study tests whether wearing virtual reality glasses during an IUD insertion procedure can help reduce pain and anxiety. You would wear the glasses during the procedure to see if they help you feel calmer and experience less discomfort.
MalatyaAges 18–49 - NCT07540663Enrolling by invitation
Stem cells to improve spinal cord stimulation pain relief
This trial tests whether stem cells injected near your spinal cord can improve pain relief from your existing spinal cord stimulator (BurstDR device). You're only eligible if your current stimulator is already helping with at least 50% pain reduction.
Hasselt, LimburgAges 18 years+ - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT07535879Enrolling by invitation
Neck Pain Treatment Using Pressure Feedback for Teachers
This study tests whether using pressure feedback (a device that gives you information about muscle tension) while doing neck exercises helps reduce neck pain in teachers. Researchers want to see if this technique strengthens deep neck muscles and improves your symptoms.
Istanbul, KüçükçekmeceAges 22–65 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07524010Enrolling by invitation
Electrolysis Treatment for Lower Back Pain in Active Men
This study tests a needle-based treatment called percutaneous electrolysis on the muscles in your lower back to reduce pain. Researchers will analyze how your body responds to understand why it might help with back pain.
VercelliAges 18 years+ - NCT07518732Enrolling by invitation
Thoracic Spine Treatment: Massage and Manipulation Study
This study tests whether hands-on treatments—spinal manipulation and massage—can reduce back pain, improve flexibility, and help with sleep in older adults with long-standing mid-back problems. You would receive these treatments over time and answer questions about your pain and sleep.
IstanbulAges 18–65 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT07502573Enrolling by invitation
Comparing two exercise programs for piriformis syndrome
This trial compares a home exercise program with a telerehabilitation program for people with piriformis syndrome. Researchers want to see which approach helps reduce pain and improve function better.
Ankara, KeciorenAges 18–45 - NCT07489014Enrolling by invitation
Therapy techniques for neck pain relief
This trial tests two hands-on treatments—gentle joint movement and soft tissue release—to see which better helps long-lasting neck pain. It could offer pain relief without surgery or strong medications.
IstanbulAges 18–65 - NCT07485426Enrolling by invitation
Activity and pain management for teens with chronic pain
This study tests an online program to help teens manage chronic pain and improve daily functioning. It uses acceptance and commitment therapy (ACT) to build coping skills and reduce suffering.
Linköping, Östergötland CountyAges 13–19 - NCT07477847Enrolling by invitation
Custom exercise for back pain, posture, and quality of life
This study tests a personalized exercise program to see if it reduces back pain, improves posture (kyphosis angle), and boosts quality of life. It may help if you have nonspecific back pain and haven't been exercising regularly.
IstanbulAges 18–45 - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07450781Enrolling by invitation
How saline temperature and local anesthetics affect shoulder pain after gallbladder surgery
This trial tests whether warming the saline used during surgery or adding a numbing medicine can reduce shoulder pain after laparoscopic gallbladder removal. It also checks how these affect inflammation markers in the blood.
AlexandriaAges 18–65 - NCT07432685Enrolling by invitation
Can movement predict chronic pain after combat limb injuries?
This study is looking for people with combat-related arm or leg injuries to see if how they move can predict long-term pain. Researchers hope to better understand who might develop chronic pain and help improve treatment.
LvivAges 18–50 - NCT07432074Enrolling by invitation
Acupressure and massage after cesarean section
This study tests whether acupressure (gentle pressure on specific points) or massage can help women recover after a planned cesarean. It aims to reduce pain and improve comfort without using extra medicine.
IstanbulAges 18–45 - NCT07404813Enrolling by invitation
Do family voices affect brain chemistry and pain in ICU patients?
This study tests whether hearing a family member's voice can change natural brain chemicals (dopamine and serotonin) and reduce pain for people in the intensive care unit who are in a coma but can still react. It may help improve comfort during recovery.
Malatya, MalatyaAges 18–65 - NCT07393503Enrolling by invitationPhase 4
Pain relief for new muscle and joint injuries
This trial compares two common treatments for new muscle or joint pain: an over-the-counter pain reliever (Tylenol and ibuprofen) versus an oral steroid (a stronger anti-inflammatory medication). The goal is to see which option works better for short-term pain and recovery.
Buffalo, New YorkAges 18 years+ - NCT07380139Enrolling by invitationPhase 1
Comparing two medications for nose surgery pain relief
This trial tests if two different medicines, dexamethasone and dexmedetomidine, given as a nerve block in your nose during rhinoplasty can better control pain after surgery.
CairoAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.