Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07606781Recruiting
Nerve Blocks for Pain Relief During Hysterectomy Surgery
This study tests two types of nerve-blocking injections given during abdominal hysterectomy (removal of the uterus) to reduce pain and opioid use after surgery. The goal is to help you recover more comfortably with fewer strong pain medications.
Tanta, El-GharbiaAges 18 years+ - NCT07605754Recruiting
Nerve Surgery Results for Pain After Amputation
This study evaluates how well nerve surgery works for patients with severe, persistent pain in the area where a limb was amputated. Researchers will review outcomes to understand if this surgical approach helps reduce pain that hasn't responded to other treatments.
Leiden, South HollandAges 18 years+ - NCT07603960Recruiting
Cold therapy to ease endometriosis pelvic pain
This study tests whether exposing your whole body to very cold air (below freezing) can reduce chronic pelvic pain from endometriosis and improve your quality of life. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain.
Edinburgh, ScotlandAges 16 years+ - NCT07604376Recruiting
Nerve Block Pain Relief After Cesarean Delivery
This study tests whether a nerve-numbing injection in the abdomen helps reduce pain after a cesarean (C-section) delivery. The injection uses a local anesthetic to numb the area around your surgical wound, potentially reducing pain and the need for stronger pain medicines after surgery.
Târgu Mureş, Mureș CountyAges 18 years+ - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT07603609Recruiting
Balance Platform Training for Chronic Low Back Pain
This study tests whether training on a special moving balance platform can help reduce chronic low back pain. You'll practice exercises designed to improve your balance and core stability over several weeks.
AnkaraAges 18–55 - NCT07604948Recruiting
Blood Flow Restriction Training for Basketball Recovery
This study tests whether briefly restricting blood flow to the legs (using an arm cuff on the thigh) can help male basketball players recover faster and improve leg strength after games. Researchers want to see if this technique, called ischemic preconditioning, reduces fatigue and speeds healing.
Guangzhou, GuangdongAges 18–25 - NCT07604506Enrolling by invitation
Ultrasound nerve block training for junior emergency doctors
This study teaches junior doctors in emergency medicine how to use ultrasound to safely perform nerve blocks—a pain-relief technique. Researchers will compare learning with a low-cost practice model to see if it works as well as expensive alternatives.
Kubang Kerian, KelantanAges Any age - NCT06713044Recruiting
Quran recitation or music for pain after leg surgery
This trial tests whether listening to Quranic recitation or classical music can reduce pain and inflammation after lower-leg orthopedic surgery. It may help Muslim patients manage pain without extra medication.
Purwokerto, Central JavaAges 18–60 - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT06519136Recruiting
Second level Reiki for pain and quality of life in dialysis
This study tests whether a second level of Reiki (a gentle energy healing practice) can help reduce pain and improve quality of life for people on dialysis. If you already received Reiki level 1 in a previous round of this study, you may be able to join.
ÇorumAges 28–84 - NCT06690307RecruitingPhase 4
Comparing two pain medicines after laparoscopic hysterectomy
This study compares two pain medicines, oxycodone and sufentanil, given through a pump you control after a laparoscopic hysterectomy. The goal is to see which one provides better pain relief with fewer side effects.
Nantong, JiangsuAges 18–65 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07602452Recruiting
Pain Relief Methods After Colorectal Surgery
This study compares two different numbing techniques (nerve blocks) to help manage pain after open colorectal surgery. Both methods are injected near muscles in your abdomen to reduce the need for strong painkillers after surgery.
CairoAges 18–75 - NCT07600892Enrolling by invitation
Pain-at-Work Toolkit for managing chronic pain at work
This study tests a toolkit designed to help working adults manage chronic pain while on the job. The toolkit aims to make work more manageable and enjoyable for people living with ongoing pain.
Nottingham, NottinghamshireAges 18 years+ - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07596823Recruiting
Blood counts and nerve pain relief after a nerve block
This study looks at how blood cell counts change when you receive a nerve-blocking injection for neuropathic pain (nerve damage pain). Researchers want to understand if these blood changes can predict how well the injection will help your pain.
Ankara, CankayaAges 18 years+ - NCT07603154Enrolling by invitation
Massage therapy for superior cluneal nerve pinching
This trial tests a specific massage technique called 'Fenjin Tuina' for treating superior cluneal nerve entrapment syndrome, a condition where a nerve in the lower back and hip area becomes pinched or compressed. The study aims to see if this traditional Chinese massage approach can reduce pain and improve function.
Guangzhou, GuangdongAges 18–70 - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07600437Recruiting
Muscle and Joint Problems in Musicians Study
This research study examines how common muscle, joint, and bone problems are among people who play musical instruments. Researchers will ask you questions and may do physical assessments to understand which musicians are most affected and why.
Multiple LocationsAges 18 years+ - NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT07597343Recruiting
Helping You Stick With Hip Pain Exercise Treatment
This study tests new ways to help people with lateral hip pain (pain on the outer side of the hip) stay motivated and consistent with their exercise program. The goal is to understand what helps patients do their exercises regularly so they can feel better.
Leicester, LeictershaireAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.