Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07595718Recruiting
Using health data and AI to predict major diseases
This study uses your health information and artificial intelligence to help predict the onset of major diseases. By joining, you could help improve early detection and prevention for conditions like diabetes, heart disease, and cancer.
Seoul, Seoul Special CityAges 30–65 - NCT06167330Recruiting
Titan trial: Reducing phantom limb pain
This trial tests a new method to reduce phantom limb pain (pain felt in a missing limb) using gentle electrical stimulation and simple mental exercises. It is for people with one-sided amputations who have had phantom limb pain for at least three months and still have pain episodes now.
Randwick, New South WalesAges 18 years+ - NCT06569836Recruiting
Study on digital program for chronic knee pain
This trial tests a digital program to help people manage chronic knee pain. If you are 55 or older and have had knee pain recently, this study may be a good fit.
Hong KongAges 55 years+ - NCT02533804Recruiting
Life Project study for adults in Lake Nona
This study is collecting information from adults living or working in the Lake Nona area. It may help researchers understand community needs and improve programs for residents.
Orlando, FloridaAges 18–110 - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT07593313Recruiting
Treatment for pain after stroke using spinal stimulation
This trial tests a treatment called spinal cord stimulation for people who develop chronic pain after a stroke. The pain is caused by the stroke itself and doesn't respond well to regular pain medicines. The treatment uses a small device to send mild electrical signals to your spinal cord to reduce pain.
Nanchong, SichuanAges 18 years+ - NCT07590752RecruitingPhase 2/Phase 3
Pain Relief Comparison for Abdominal Surgery
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
Sahiwal, Punjab ProvinceAges 25–65 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT07591233Recruiting
Pain Relief Injection During Laparoscopic Surgery
This trial tests whether injecting a numbing medication mixed with a steroid into the surgical area before making cuts can reduce pain after common laparoscopic procedures like gallbladder removal or hernia repair. The goal is to help patients recover with less pain and fewer pain medications.
Beijing, Beijing MunicipalityAges 18–64 - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07588165Recruiting
Measuring Pain During Emergency Breathing Tube Placement
This study tests a pain-monitoring device during emergency anesthesia for stomach or abdominal surgery. Researchers want to see how well the device (called ANI) detects pain when doctors quickly put a breathing tube in your airway.
MonacoAges 18 years+ - NCT07590323Recruiting
Blood Flow Restriction Training for Knee Osteoarthritis
This study tests whether a special training method called blood flow restriction (BFR)—which uses a cuff to safely limit blood flow while you exercise—can help reduce knee osteoarthritis pain and improve function. You'll do supervised exercises three times a week for 8 weeks.
Ha'il, Ha'il RegionAges 40–70 - NCT07586462Recruiting
Deep Nerve Block for Abdominal Surgery Pain Relief
This trial tests a nerve block—a targeted numbing injection near abdominal muscles—to help reduce pain after abdominal surgery. Researchers want to see if this technique works well alongside standard anesthesia to help you recover more comfortably.
CrotoneAges Any age - NCT07587970Recruiting
Body Position and Oxygen Levels During Sedated Scope Procedures
This study tests whether your body position during recovery from sedated endoscopy (a camera procedure to examine your stomach and colon) affects your oxygen levels. The researchers want to find the best recovery position to keep your oxygen levels stable and safe.
Yinchuan, NingxiaAges 18 years+ - NCT07591207Recruiting
Pain relief patch after laparoscopic abdominal surgery
This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–64 - NCT07588061Recruiting
Neck Pain Treatment: Mobilization and Posture Exercises
This study tests whether combining two types of physical therapy—manual joint mobilization and specific posture-strengthening exercises—can reduce neck and upper back pain and improve how you hold your body. You may qualify if you have persistent neck pain linked to poor posture.
Peshawar, KPKAges 18–45 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07587190Recruiting
Testing new guidelines for sudden severe stomach pain in Zambia
This study tests whether new medical guidelines help doctors better diagnose and treat sudden severe stomach pain in primary care clinics in Zambia. Researchers will compare how well the new guidelines work by looking at patient outcomes at two different health centers.
Lusaka, Lusaka ProvinceAges 18 years+ - NCT07591324Recruiting
3D-Printed vs. Traditional Space Holders for Kids' Teeth
This study compares two types of dental devices that hold space in a child's mouth after baby molars fall out early. The research tests whether a newer 3D-printed version works as well as or better than the traditional wire-based device.
Ismailia, Ismailia GovernorateAges 7–9 - NCT07588490Recruiting
TENS for sudden severe lower back pain in the emergency room
This trial tests a pain-relief device called TENS (a small machine that sends mild electrical pulses through your skin) for people with sudden, severe lower back pain in the emergency department. Researchers want to see if TENS can help reduce your pain quickly without extra medications.
BrusselsAges 18 years+ - NCT07593235Recruiting
Treating Forward Head Posture with Two Physical Therapy Techniques
This study compares two hands-on treatment methods for forward head posture—a common problem where your head juts forward. Researchers want to see which technique works better at improving your posture and reducing strain on your neck and upper back.
Islamabad, Punjab ProvinceAges 18–40 - NCT07593183Recruiting
Spine exercises and telehealth for postpartum lower back pain
This trial tests whether guided spine-strengthening exercises (done at home via video or in-person) can reduce lower back pain and improve posture in women recovering from childbirth. Researchers measure the curve of your lower spine and track pain relief over time.
Islamabad, Punjab ProvinceAges 20–40 - NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.