Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07590674Recruiting
Balance training for competitive tennis players
This study compares two types of balance training to see which one better improves tennis players' ability to move quickly and change direction on court. You'll do either reactive balance exercises (responding to sudden movements) or traditional balance exercises over the study period.
IslamabadAges 18–25 - NCT07586462Recruiting
Deep Nerve Block for Abdominal Surgery Pain Relief
This trial tests a nerve block—a targeted numbing injection near abdominal muscles—to help reduce pain after abdominal surgery. Researchers want to see if this technique works well alongside standard anesthesia to help you recover more comfortably.
CrotoneAges Any age - NCT07591233Recruiting
Pain Relief Injection During Laparoscopic Surgery
This trial tests whether injecting a numbing medication mixed with a steroid into the surgical area before making cuts can reduce pain after common laparoscopic procedures like gallbladder removal or hernia repair. The goal is to help patients recover with less pain and fewer pain medications.
Beijing, Beijing MunicipalityAges 18–64 - NCT06718374Recruiting
Chest pain differences in diabetic vs non-diabetic patients
This study compares how chest pain feels in people with and without diabetes after a heart attack. It aims to understand if diabetes changes the symptoms, which could help doctors diagnose faster.
Asyut, Asyut GovernorateAges Any age - NCT06722742RecruitingPhase 3
Preventing shivering after spinal anesthesia for cesarean
This trial tests whether two common medicines, tramadol and ketamine, given through an IV, can prevent shivering that sometimes happens after spinal anesthesia for cesarean section. You may be able to join if you are having a planned cesarean and are generally healthy.
Karachi, SindhAges 18–40 - NCT07578610Recruiting
Registry study of symptom descriptions using OpenGenome platform
This is an observational registry study that collects and analyzes symptom descriptions from patients using the OpenGenome platform. The goal is to better understand and extract health information from how people naturally describe their symptoms.
Friedrichshain, State of BerlinAges 18 years+ - NCT07578545Recruiting
Pain management after minimally invasive chest surgery
This study tests whether combining a specific type of chest surgery (using small cameras) with numbing injections around nerves reduces pain and the need for strong pain medications after surgery. Researchers want to see if this approach helps patients recover better with less opioid use.
Antalya, MuratpaşaAges 18–75 - NCT07577869Recruiting
Nerve blocks for pain relief after knee replacement
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Kayseri, KocasinanAges 18–80 - NCT06715761Recruiting
Myofascial release for chronic low back pain in CrossFit athletes
This trial tests if a hands-on or tool-assisted muscle release technique can reduce long-term low back pain and improve posture in people who do CrossFit. If you have had low back pain for at least 12 weeks and do CrossFit regularly, this study may help you find relief.
Goiânia, GoiásAges 18–59 - NCT07577492Recruiting
Neck Position Sense and Balance in Students With Rounded Shoulders
This study examines how neck position awareness, core strength, and balance are affected in university students with Upper Crossed Syndrome—a posture problem involving forward head position and rounded shoulders. The research may help identify better treatments for chronic neck pain linked to poor posture.
Istanbul, TopkapiAges 18–30 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07578168Enrolling by invitation
Kinesio Tape for Rotator Cuff Shoulder Pain
This study tests whether kinesiology tape (a special stretchy tape applied to the skin) can reduce pain and improve function in people with rotator cuff syndrome, a common shoulder condition. You'll be randomly assigned to receive the tape or a control treatment and tracked over several weeks.
Kırşehir, MerkezAges 18–65 - NCT07581535Recruiting
Neck and Eye Exercises for Chronic Ankle Instability
This study tests whether specific exercises for your neck and eye movements can help improve balance and stability in ankles that frequently give way or feel unstable. The goal is to see if these exercises reduce symptoms and improve your ankle function.
Izmir, ÇiğliAges 18–45 - NCT07578376Recruiting
Pain Relief Program for Cancer Survivors
This study tests an online pain-management program called Empowered Relief® designed specifically for cancer survivors dealing with chronic pain. You'll complete surveys and attend virtual classes to learn techniques that may help reduce your daily pain.
Tulsa, OklahomaAges 18–120 - NCT07579039Recruiting
Stretching and tape for pregnancy back pain
This study tests whether combining stretching exercises with special therapeutic tape can safely reduce lower back pain during pregnancy. If it works, it could offer pregnant women a non-medication option to feel better.
Rahim Yar Khan, Punjab ProvinceAges 18–35 - NCT07578935Recruiting
Stability and Jump Training After ACL Surgery
This study compares two types of exercise programs for people who had ACL (knee ligament) reconstruction surgery 1-3 years ago. The goal is to see which training approach—focusing on balance and stability or on jumping and power—helps restore better knee function and strength.
Lahore, Punjab ProvinceAges 20–40 - NCT07578181Enrolling by invitation
Aromatherapy Massage for Chronic Lower Back Pain
This study tests whether massage combined with essential oils (lavender, orange, and almond oil) can help reduce chronic lower back pain that has lasted at least 6 months. Researchers want to see if aromatherapy massage is a safe and helpful treatment option.
Kırşehir, MerkezAges 18–65 - NCT07578831Recruiting
Neck Pain Relief: Comparing Two Exercise Methods
This study compares two types of therapeutic exercises—Kendall and Feldenkrais—to help reduce neck pain and improve posture in people with upper crossed syndrome (a common postural condition where neck and shoulder muscles become tight and weak). You'll do one type of exercise program to see which helps your neck pain and function better.
Lahore, Punjab ProvinceAges 20–50 - NCT07578324Recruiting
TENS to reduce pain during prostate biopsy
This study tests whether TENS (a gentle electrical stimulation applied to the skin) can help reduce pain when combined with numbing medicine during a prostate biopsy procedure. The goal is to see if this may make the biopsy more comfortable for patients.
Gdansk, Pomeranian VoivodeshipAges 40 years+ - NCT07585721Recruiting
Pain Relief After Root Canal Treatment: Two Different Medications
This study compares two types of medications placed inside a tooth after root canal treatment to see which one reduces pain better. You'll be asked about your pain levels after treatment, and researchers will measure a pain-related substance in your saliva.
CairoAges 18–45 - NCT07581080Recruiting
Biofield therapy to ease fatigue from cancer immunotherapy
This study tests whether Reiki—a hands-on healing practice—can help reduce severe tiredness in cancer patients receiving immunotherapy drugs. If it works, it could offer patients another way to manage fatigue alongside their cancer treatment.
Irvine, CaliforniaAges 18 years+ - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT06723730Recruiting
Mobilization and core strength for rotator cuff pain
This trial tests if adding a specific type of shoulder movement therapy and upper body core exercises can reduce pain and improve function in people with rotator cuff-related shoulder pain. It may help you if you have had shoulder pain for more than 6 weeks and it started after an injury.
Rawalpindi, Punjab ProvinceAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.