Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07537127Recruiting
Lidocaine to reduce shoulder pain after single-port surgery
This trial tests whether lidocaine (a numbing medication) injected during a minimally invasive single-port abdominal surgery can reduce shoulder pain after the procedure. Shoulder pain is a common side effect of this type of surgery, and the study aims to find a simple way to prevent it.
Beijing, Beijing MunicipalityAges 18–65 - NCT07538427Recruiting
Music Therapy for Health in Rural Elder Care
This study explores whether music can improve health and wellbeing in older adults living in rural care facilities. Researchers will work with residents to understand how music might help with mood, memory, and quality of life.
Flagstaff, ArizonaAges Any age - NCT07539623RecruitingPhase 3
Pain relief with suzetrigine after heart or weight-loss surgery
This study tests whether suzetrigine, a new pain medication, can reduce the need for opioids (strong painkillers) after cardiac or bariatric surgery. The goal is to help patients manage pain with fewer opioid-related side effects.
New York, New YorkAges 18–85 - NCT07540663Enrolling by invitation
Stem cells to improve spinal cord stimulation pain relief
This trial tests whether stem cells injected near your spinal cord can improve pain relief from your existing spinal cord stimulator (BurstDR device). You're only eligible if your current stimulator is already helping with at least 50% pain reduction.
Hasselt, LimburgAges 18 years+ - NCT07534956Recruiting
Anesthesia Methods and Waking Up Agitation in Children
This study compares different anesthesia approaches to see which one helps children wake up more calmly after urogenital surgery (surgery on the urinary or reproductive system). Researchers want to find the best way to reduce agitation and confusion as children wake up from anesthesia.
IstanbulAges 3–10 - NCT07542470Enrolling by invitationPhase 4
Cold and compression therapy after spinal surgery
This study compares a new cold and compression device (NICE1) to standard care after spinal surgery to see if it reduces pain and swelling. If you're having spine surgery, this trial tests whether keeping the area cold and compressed helps you recover better.
Sarasota, FloridaAges 18 years+ - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT07540689Recruiting
Pain Relief Method for Children's Minimally Invasive Belly Surgery
This study tests a new pain-relief technique called M-TAPA for children ages 1–7 having small-incision belly surgery. Researchers want to see if this method helps reduce pain better than standard approaches after surgery.
Cairo, ElmanialAges 1–7 - NCT07535047Recruiting
How Placebo and TENS Work Together for Lower Back Pain
This study tests whether the expectation of pain relief (the placebo effect) can make a device called TENS (transcutaneous electrical nerve stimulation) work better for acute lower back pain. TENS uses gentle electrical pulses on your skin to reduce pain.
Giza, Giza GovernorateAges 18–65 - NCT07535697Recruiting
Pain relief methods after lung surgery: two approaches compared
This study compares two ways to reduce pain after minimally invasive lung surgery (VATS). Researchers test whether numbing the chest wall with ultrasound guidance works as well as numbing nerves seen during surgery to help you recover more comfortably.
Offenbach, HesseAges 18 years+ - NCT07535879Enrolling by invitation
Neck Pain Treatment Using Pressure Feedback for Teachers
This study tests whether using pressure feedback (a device that gives you information about muscle tension) while doing neck exercises helps reduce neck pain in teachers. Researchers want to see if this technique strengthens deep neck muscles and improves your symptoms.
Istanbul, KüçükçekmeceAges 22–65 - NCT07536399RecruitingPhase 3
Bone Marrow Treatment for Jaw Joint Pain Relief
This study tests whether injecting your own bone marrow cells into your jaw joint during a minimally invasive procedure can reduce pain and improve jaw function better than arthroscopy alone. It's for people with significant jaw pain that hasn't improved with conservative treatments like NSAIDs, physical therapy, and bite splints.
New York, New YorkAges 18–75 - NCT07542392Recruiting
Birth Affirmation Cards to Support First-Time Labor
This study tests whether special affirmation cards (positive statements) guided by a midwife help first-time mothers feel more confident and positive during labor. The goal is to see if this simple, non-medical tool improves your labor experience and how you cope with contractions.
Mut, Mersi̇nAges 18–40 - NCT07535281Recruiting
Kidney Stone Surgery Technique and Recovery Study
This study tests a technique during kidney stone removal surgery (RIRS) where the surgeon fully drains the kidney system at the end of the procedure. Researchers want to see if this approach improves how quickly patients recover and reduces complications.
Gandong-gu, Outside U.S./CanadaAges 20–80 - NCT07537036Recruiting
Pain Relief Methods for Hip Replacement Surgery
This trial compares two nerve-blocking techniques to reduce pain after hip replacement surgery. Both methods use numbing medication around specific areas near your hip to help you feel more comfortable after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT06750211Recruiting
Muscle techniques for chronic neck pain
This study tests two types of gentle muscle-relaxing techniques for long-term neck pain with forward head posture. It compares one technique alone versus the same technique combined with a specific exercise to see which works better.
LahoreAges 20–50 - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT06320262Recruiting
Wet cupping (Hijama) for fibromyalgia pain
This trial tests whether wet cupping (Hijama) can help reduce pain in women with fibromyalgia. It is for women who have had moderate to severe pain and have not taken certain pain medications in the past year.
CairoAges 18–55 - NCT07533786RecruitingPhase 2
New Pain Medicine After Abdominal Surgery
This study tests a new medication called HSK55718 to treat pain after abdominal surgery. If you're having moderate to severe pain within 4 hours of surgery, this trial may help you get relief and contribute to finding better pain treatments.
Changsha, HunanAges 18 years+ - NCT04843865Recruiting
Chinese herbal add-on for joint pain from letrozole
This trial studies whether Chinese herbs, used alongside letrozole, can reduce ongoing joint and muscle pain or stiffness in postmenopausal women with hormone-receptor positive breast cancer. It’s mainly for people whose pain started or worsened after beginning letrozole and who have completed cancer treatments.
Bukit Bintang, Kuala LumpurAges 18 years+ - NCT07528482Recruiting
Reflexology and cold therapy for chest tube removal pain
This study tests whether foot massage (reflexology) and cold application can reduce pain when chest tubes are removed after heart bypass surgery. Researchers want to see if these complementary techniques help manage discomfort during this procedure.
AnkaraAges 18 years+ - NCT07531537Recruiting
Breathing exercises versus neck muscle training for neck pain
This study compares two types of exercises—breathing exercises and deep neck muscle training—to see which works better for people with long-term neck pain. You'll do one type of exercise program to help relieve your pain and improve function.
ZagazigAges 18–35 - NCT07526831Recruiting
Pain Relief Methods for Knee Surgery: Two Nerve Block Approaches
This study compares two ways of numbing nerves around the knee during surgery to see which method reduces pain better after the operation. Both methods use safe, well-established pain-relief techniques.
Kayseri, TalasAges 18 years+ - NCT07526051Recruiting
Stretching techniques for lower back pain and muscle tightness
This study compares two stretching methods to help relieve lower back pain caused by muscle imbalances. You'll be tested to confirm the pattern of muscle tightness, then receive one of two types of stretching therapy to see which works better for your pain.
Islamabad, Punjab ProvinceAges 25–50
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.