Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07526051Recruiting
Stretching techniques for lower back pain and muscle tightness
This study compares two stretching methods to help relieve lower back pain caused by muscle imbalances. You'll be tested to confirm the pattern of muscle tightness, then receive one of two types of stretching therapy to see which works better for your pain.
Islamabad, Punjab ProvinceAges 25–50 - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT07528482Recruiting
Reflexology and cold therapy for chest tube removal pain
This study tests whether foot massage (reflexology) and cold application can reduce pain when chest tubes are removed after heart bypass surgery. Researchers want to see if these complementary techniques help manage discomfort during this procedure.
AnkaraAges 18 years+ - NCT07525453Recruiting
Exercise Programs to Improve Balance in Older Adults
This study tests three different exercise programs designed to help older adults improve their balance and reduce fall risk. You'll participate in one of the programs and have your balance tested before and after to see which approach works best.
Istanbul, AtaşehirAges 65 years+ - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07527039RecruitingPhase 4
Nerve Block for Pain Relief During Breast Reduction Surgery
This study tests a special numbing technique (pectoral block) to help control pain after breast reduction surgery in women with very large breasts causing symptoms like neck, shoulder, or back pain. The goal is to see if this nerve block reduces pain better than standard pain control methods.
Roanoke, VirginiaAges 18–75 - NCT07525219RecruitingPhase 3
Pain Relief During Stereotactic Head Frame Placement
This study compares a new pain medication called suzetrigine with acetaminophen (Tylenol) for patients who need a stereotactic head frame placed as part of their scheduled medical procedure. The frame holds your head still during brain imaging or treatment.
Winston-Salem, North CarolinaAges 21 years+ - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT07525557Recruiting
Understanding Fear and Disability in Long-Term Neck Pain
This study explores how fear of movement, pain, and daily difficulties relate to each other in people with chronic neck pain lasting 3+ months. Understanding these connections may help improve future treatment approaches.
Samsun, SamsunAges 18 years+ - NCT07531537Recruiting
Breathing exercises versus neck muscle training for neck pain
This study compares two types of exercises—breathing exercises and deep neck muscle training—to see which works better for people with long-term neck pain. You'll do one type of exercise program to help relieve your pain and improve function.
ZagazigAges 18–35 - NCT07529392Recruiting
Ear nerve stimulation plus rehabilitation for chronic back pain
This trial tests a non-surgical treatment that stimulates a nerve in your ear while you do rehabilitation exercises to reduce chronic back pain. It may help if you've had pain for more than 6 months and pain medications aren't working well enough.
Baden, Lower AustriaAges 30–65 - NCT07526038Recruiting
Physical therapy for postpartum pelvic joint pain
This study tests whether a hands-on movement technique combined with core exercises helps postpartum mothers with sacroiliac joint pain (a pain in the lower back/buttock area). The research compares this combined approach to see if it reduces pain and improves function.
Islamabad, Punjab ProvinceAges 20–40 - NCT07533669Recruiting
Sensory room visit before kidney transplant surgery
This study tests whether spending time in a calming sensory room before kidney transplant surgery helps reduce pain, anxiety, and sleep problems. You would visit a specially designed room with soothing sights, sounds, and textures before your operation.
SakaryaAges 18 years+ - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+ - NCT07532070Recruiting
Exercise and Therapy for Chronic Pain and Sleep Problems
This study tests whether exercise, talk therapy for sleep problems, or both together can help people with long-term back, hip, or knee pain who also struggle with sleep. You'll attend video appointments and try one of these approaches for several weeks.
San Antonio, NevadaAges 18 years+ - NCT06684275Recruiting
Radiofrequency treatment comparison for trigeminal neuralgia pain
This trial compares two types of radiofrequency treatment (pulsed and thermal) to see which works better for people with trigeminal neuralgia, a condition that causes severe, stabbing facial pain. If you have had facial pain for at least six months that isn't controlled by medicine, this study may help you find relief.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06696300Recruiting
Breathing muscle training for chronic low back pain
This study tests whether training the muscles you use to breathe can help reduce chronic low back pain. You will practice specific breathing exercises and see if they improve your pain and function.
Kırşehir, CenterAges 18–65 - NCT06753487Recruiting
Comparing two gentle therapies for piriformis syndrome in women
This trial tests two hands-on treatments (Facilitated Positional Release and Manual Myofascial Release) to see which works better for women with piriformis syndrome. If you're a woman aged 25–50 with buttock or hip pain for at least 2 months, this study might help you find relief.
Rawalpindi, Punjab ProvinceAges 25–50 - NCT06753019Recruiting
Knee Osteoarthritis: Thoughts, Feelings, and Function
This study looks at how your thoughts and feelings about knee pain (and your daily function) relate to osteoarthritis. It aims to help understand your overall health better.
IspartaAges 40–84 - NCT07519109RecruitingPhase 1
SYH9089 for pain after abdominal surgery
This study tests an injected medicine (SYH9089) to see if it safely controls pain after abdominal surgery. It may help you recover with less discomfort.
Changsha, HunanAges 18–75 - NCT07524270Recruiting
Testing a supplement for period pain and PMS symptoms
This study tests a product called Effera to see if it helps reduce menstrual cramps, pain, and premenstrual symptoms like mood changes and bloating. You'll track your symptoms and complete online surveys over several weeks.
San Francisco, CaliforniaAges 18–40 - NCT06756516Recruiting
Feldenkrais Method for balance and back pain relief
This trial tests if the Feldenkrais Method, a gentle movement therapy, can improve balance and reduce pain in people with long-term mechanical back pain. It may be a good option if you've had back pain for at least 6 months and it doesn't shoot past your knee.
GizaAges 18–45 - NCT06426706Recruiting
Nerve Blocks for Pain After VATS Lung Surgery
This study compares two types of nerve blocks (TPVB and SPSIPB) to see which is better at controlling pain after keyhole lung surgery. If you are having VATS, the trial may help you have less pain and recover more comfortably.
IstanbulAges 18–80 - NCT06409689Recruiting
Oliceridine for pain relief after upper abdominal surgery
This study tests a new pain medicine called oliceridine after laparoscopic upper abdominal surgery. It aims to improve pain control and recovery compared to standard opioids.
Wuhan, HubeiAges 18–70
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.