Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07402161Recruiting
Finding Alzheimer's earliest signature in memory concerns
This study looks for early signs of Alzheimer's in people who feel their memory is slipping but still function normally. You'll help researchers find a pattern—a 'signature'—in the brain that may signal the earliest stages of the disease.
San Donato Milanese, MilanAges 18 years+ - NCT07404410Recruiting
Robot therapy for apathy in dementia
This study tests whether a friendly robot can help reduce apathy (loss of interest) in people with dementia. You and your caregiver will use the robot at home for several weeks.
Milan, ItalyAges 40 years+ - NCT07402928Recruiting
Dopamine signals in health and Parkinson's
This study uses MRI scans to look at dopamine signals in the brain. The goal is to understand how Parkinson's affects these signals.
HvidovreAges 35 years+ - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07407400RecruitingPhase 4
Sleep medication to prevent confusion in older ICU patients
This study tests whether a sleep medication called lemborexant can help older patients in the ICU sleep better and prevent post-surgery confusion. It may be a good fit if you are over 65 and will be in the ICU for at least two days after surgery.
BangkokAges 65 years+ - NCT07398599Recruiting
Double-dose targeted therapy plus chemo for lung cancer spread to brain lining
This trial tests a stronger dose of an EGFR-targeted drug combined with bevacizumab and chemotherapy into the spinal fluid for patients with non-small cell lung cancer that has spread to the lining of the brain and is no longer responding to standard treatment.
Nanchang, JiangxiAges 18–99 - NCT07403747Recruiting
Using a ride-on toy car to reduce anxiety during surgery prep
This study tests if letting preschool boys ride a toy car to the operating room helps them feel less anxious. It may be a good option if your child is having tonsil or adenoid surgery for the first time.
AnkaraAges 3–7 - NCT07402447Recruiting
Leg strengthening for knee osteoarthritis and walking
This study tests if strengthening your thigh and calf muscles can improve walking in people with knee osteoarthritis. It may help you walk better and feel more stable.
Peshawar, Khyber PakhtunkhwaAges 40–60 - NCT07401147Recruiting
TENS for pain relief during first labor
This trial tests a gentle electrical device (TENS) to help manage pain during labor. It's for women having their first baby, with a healthy, single pregnancy, and no major health issues.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45 - NCT07400484Recruiting
N-CAD levels and brain function in children with autism
This study compares levels of a protein called N-CAD and brain function in children with autism spectrum disorder (ASD) versus typically developing children. It may help researchers understand how the brain works differently in autism.
Chongqing, Chongqing MunicipalityAges 3–5 - NCT07398872Enrolling by invitationPhase 1
Gene therapy trial for children with ML4
This trial tests a gene therapy given by a one-time injection into the spinal fluid for children with Mucolipidosis type IV. It aims to see if the therapy is safe and can help slow or stop the disease.
Hangzhou, ZhejiangAges 1.5 years–8 years - NCT07399496Recruiting
Fast TMS for apathy in Parkinson's disease
This study tests a faster version of TMS (transcranial magnetic stimulation) to see if it can help with apathy—low motivation and lack of interest—in people with Parkinson's disease. You will receive several TMS sessions each day over a short period, and the study team will check if your mood and motivation improve.
Charleston, South CarolinaAges 45–85 - NCT07405450Recruiting
Robotic walking training for better mobility
This study tests a robotic walking trainer (Trexo) to see if it helps improve walking. It is for people who can safely use the robot and stick to the training plan.
Calgary, AlbertaAges Any age - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07399418Recruiting
Tracking risk in integrated Alzheimer's diagnosis
This study is looking for people with or at risk for Alzheimer's disease and their caregivers. It aims to track risk factors and improve diagnosis using a combination of tests and tools.
Montescano, Pavia, ItalyAges 50 years+ - NCT07398508RecruitingPhase 1/Phase 2
Northera for dizziness and diarrhea in Menkes disease survivors
This trial tests if the drug Northera (droxidopa) can help children with Menkes disease who have dizziness when standing or chronic diarrhea. It aims to improve these symptoms by supporting blood pressure and bowel function.
New York, New YorkAges 7–17 - NCT07404384Enrolling by invitation
Slow breathing and resistance exercise for fibromyalgia
This study tests whether combining slow breathing exercises with light weightlifting (biceps curls) can help women with fibromyalgia feel better. It focuses on improving symptoms through a simple home-based routine.
Málaga, MálagaAges 18 years+ - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07401186Recruiting
Stimulation to Improve Sensory Pathways in the Brain and Spine
This study tests whether using electrical stimulation during neck surgery can help improve how the brain and spinal cord process sensory information. It may offer new ways to help people with stroke-related weakness.
Pittsburgh, PennsylvaniaAges 21–75 - NCT07405775Recruiting
SleepFix for Youth: app-based insomnia therapy with psychologist support
This study tests a smartphone app that helps young people with insomnia develop better sleep habits, with guidance from an e-psychologist. It may help you sleep better without needing in-person therapy.
Sydney, New South WalesAges 16–24 - NCT07405762Recruiting
Stroke recovery after blood clot removal: brain blood flow study
This trial looks at how blood flow and brain activity change in the first days after a stroke caused by a large blockage in the front part of the brain. It tests if certain patterns can help predict recovery after a procedure to remove the clot.
Xi'an, Shan'xiAges 18–85 - NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke
This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.
St Louis, MissouriAges 18–99 - NCT07398352Recruiting
Regional anesthesia effects on brain oxygen in shoulder surgery
This trial studies how regional anesthesia affects oxygen levels in the brain and a key artery during shoulder surgery. It aims to find which anesthesia method works best for oxygen supply.
SanliurfaAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.