Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT05468567Recruiting
Sound perception study for people with noise-related ear injury
This study looks at how people who have noise-related ear trauma perceive sounds, using a 3D (three-dimensional) sound setup. The results may help doctors better understand sound processing after acoustic injuries.
LyonAges 18–65 - NCT05469373Recruiting
Testing ESIS for children with hard-to-treat epilepsy
This trial studies ESIS in children and teens (ages 1 to 30) who have epilepsy that has not been controlled by medications. It may help by improving how doctors evaluate and treat seizures, especially when an additional brain-monitoring test is planned.
Cincinnati, OhioAges 1–30 - NCT05471232Recruiting
Genomic testing for youth mental health crises with IDD
This study looks at genetic (DNA) information to understand mental health crises in youth with intellectual and developmental disabilities. It may help doctors learn why these crises happen and improve how future families are supported.
San Diego, CaliforniaAges 7–17 - NCT05472584Recruiting
Spinal stimulation with training for leg movement after injury
This study tests whether spinal cord stimulation combined with training can improve your ability to move your legs and do daily tasks. You may be able to join if you have a traumatic incomplete spinal cord injury (or, in some cases, if you’re a healthy volunteer).
St Louis, MissouriAges 16–65 - NCT05473637Recruiting
Study causes of small vessel brain disease in stroke and memory issues
This trial looks at people who may have “small vessel” problems in the brain, which can cause stroke, memory trouble, walking changes, movement symptoms, or headaches. It may help researchers better understand the genetic and non-genetic causes, which could improve future diagnosis and treatment.
TaipeiAges 18 years+ - NCT05473429Recruiting
Study how pain works in people with intellectual disability
This study measures how you feel pain (nociception) and compares patterns in people with intellectual disability and healthy volunteers. It may help researchers better understand pain differences and improve future pain care.
Bethesda, MarylandAges 8–30 - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT05474066Recruiting
Testing brain function changes before and after deployment
This study looks at how the brain’s attention and information-processing skills change around major military changes. It may help researchers better understand who is affected and how to support performance and recovery.
Ottawa, OntarioAges 18–65 - NCT05474573Recruiting
Laser-guided removal of brain tumors using special light
This study tests a method to help surgeons find and remove brain tumors that show up on MRI with contrast dye (often high-grade gliomas and brain metastases). If you newly have one of these tumors, the trial may help improve how completely tumors can be removed while protecting important brain areas.
MoscowAges 18–79 - NCT05474235Recruiting
ALS and motor neuron disease studies for patients, family, and controls
This study looks at people with amyotrophic lateral sclerosis (ALS), people who might have ALS, and also people related to someone with ALS. It may help researchers better understand ALS and related “motor neuron” conditions, and it involves participation that may include blood tests.
Jacksonville, FloridaAges 18 years+ - NCT05474378RecruitingPhase 1
CAR T cell therapy for recurrent glioblastoma
This early-phase study tests a type of immune-cell treatment (CAR T cells) aimed at a target called B7-H3 in people with glioblastoma or related grade 4 brain tumors that have come back. It’s meant to see if the treatment can shrink the tumor or control the disease and to learn how safe it is.
Palo Alto, CaliforniaAges 18 years+ - NCT05474963Recruiting
Trial for sudden hearing loss within days
This trial is for adults who develop sudden hearing loss over a very short time window, confirmed by a hearing test. It aims to study the sudden hearing loss condition and whether the study approach can help people recover hearing.
Wŏnju, Gangwon-doAges 20–100 - NCT05475262Recruiting
Inpatient sleep study using white noise
This study looks at whether playing white noise helps people sleep better while they are in the hospital. If you’re an adult admitted for several days, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT05476913Recruiting
Preventing blood clots after stroke with a leg device
This study checks whether using a special device on the legs can help prevent dangerous blood clots after an acute stroke. You may be eligible if you recently had a stroke and you’re not able to get up and walk to the toilet without help.
Bury St Edmunds, SuffolkAges 18 years+ - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05477459RecruitingPhase 2
LSD treatment for reducing the burden of cluster headaches
This Phase 2 trial tests LSD to see if it can reduce how much cluster headaches disrupt your life. You may be eligible if your cluster headaches are frequent and steady, and if you meet key safety and mental-health requirements.
LeidenAges 16–75 - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100 - NCT05479006Recruiting
tDCS for arm weakness after stroke
This trial tests whether a targeted, noninvasive brain stimulation (tDCS) can improve arm weakness and movement after stroke. It may help people who have significant trouble moving one arm on the side affected by stroke.
Urbana, IllinoisAges 18–90 - NCT05479448Recruiting
Tracking what predicts response in new PMR or GCA
This study looks at people newly diagnosed with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) and uses their health and treatment information to learn what predicts how well treatment works. It may help your care in the future by improving which patients respond best and how.
BaselAges 18 years+ - NCT05480644Recruiting
Blood biomarker study for brain tumor patients
This study collects blood (and looks at samples) from adults who have a confirmed brain tumor, either one that started in the brain or one that spread to the brain. The goal is to understand biomarkers—signals in the body—that may help improve diagnosis or tracking over time.
Durham, North CarolinaAges 18 years+ - NCT05481879RecruitingPhase 1/Phase 2
Study medicine for DM1 to improve muscle function
This early-stage study tests DYNE-101 to see how safe it is and whether it can improve measurable muscle function in people with myotonic dystrophy type 1 (DM1). You may be asked to do several walking and strength tests and undergo heart and breathing screening measurements.
Stanford, CaliforniaAges 18–65 - NCT05481749Recruiting
Neuropsychology testing for adults 80+ in Garraf
This study checks how older adults think and remember using a set of neuropsychological tests. It mainly looks at people age 80 and up living in the Garraf area who can travel to a study center.
Sant Pere de Ribes, BarcelonaAges 80 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.