Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06632743Recruiting
Austrian sarcopenia biobank study
This study collects blood and tissue samples from people with sarcopenia (muscle loss). It uses CT or MRI scans you already have planned to see how muscle changes over time. Your samples help researchers understand why muscle loss happens and how to treat it.
GrazAges 18 years+ - NCT06632860RecruitingEarly Phase 1
Testing a new PET tracer for cancer imaging
This trial tests a new imaging tracer called TATE-RGD to see if it can better spot certain tumors when used with a standard PET/CT scan. If you have cancer, you may be able to help by getting two scans a week apart.
Beijing, Beijing MunicipalityAges 18–90 - NCT06633003Recruiting
Testing an oral extract for spinocerebellar ataxia
This trial tests whether an oral extract from a mushroom called Antrodia cinnamomea can help improve symptoms in people with spinocerebellar ataxia (a condition that affects coordination and balance). Participants must be able to communicate in Chinese.
TaipeiAges 30–70 - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90 - NCT06634108RecruitingPhase 1/Phase 2
Genistein for heart failure from ATTR amyloid cardiomyopathy
This trial tests whether genistein, a plant-based supplement, can help people with a specific type of heart disease called ATTR amyloid cardiomyopathy. You might join if you have heart failure with reduced pumping function and this rare protein condition.
London, OntarioAges 40–80 - NCT06634264Recruiting
Comparing two therapies for children with sleep apnea after surgery
This study compares two different exercises (called oral reeducation) to see which works better for children who still have breathing problems during sleep even after getting their tonsils or adenoids removed. It helps kids breathe easier at night.
Montreal, QuebecAges 4–14 - NCT06634615Recruiting
Virtual reality family visits for gallbladder surgery
This study tests if using virtual reality to talk with your family before and during surgery helps reduce stress and improve recovery after gallbladder removal. Your family member will join a video call with you while you wear a VR headset.
IstanbulAges 18 years+ - NCT06634628RecruitingEarly Phase 1
Testing a new brain scan tracer for Huntington's disease
This trial tests a new radioactive tracer called [11C]CHDI-00491009 that may show mutant huntingtin protein in the brain using a PET scan. It aims to find out if the tracer is safe and helps see Huntington's disease changes. If you have early-stage Huntington's or are a healthy volunteer, you may be able to join.
LeuvenAges 18–64 - NCT06635187Recruiting
Oral-motor assessment and rehab app study
This study tests a mobile app that helps assess and train the muscles used for speaking and swallowing. It is for Cantonese-speaking adults who are either healthy or have had a stroke.
Hong Kong, Hong KongAges 20–85 - NCT06635213Recruiting
Desensitisation and pain education for carpal tunnel syndrome
This study tests whether desensitisation therapy and pain neuroscience education help people with carpal tunnel syndrome who have a type of pain called 'nociplastic' (pain without clear tissue damage). It aims to reduce pain and improve function.
KütahyaAges 18–65 - NCT06635291Recruiting
Better Diagnosis for Children with Brain Injury
This study tests new ways to evaluate children with severe brain injuries who are in a vegetative or minimally conscious state. The goal is to improve diagnosis and care for children with serious disorders of consciousness after a brain injury.
Bosisio Parini, LeccoAges 2 months–25 years - NCT06635967Recruiting
TMS for chronic tinnitus
This study tests whether repeated magnetic pulses (TMS) can help people with ongoing tinnitus. If you have had tinnitus for at least 3 months and it bothers you enough to score 38 or more on the Tinnitus Handicap Inventory (THI), you may be eligible.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06636006Recruiting
Exercise vs. digital therapy for better sleep
This study compares two treatments for insomnia: aerobic exercise and a smartphone-based cognitive behavioral therapy program. It aims to find which approach works better for people who have trouble sleeping.
Jatai, GoiásAges 18 years+ - NCT06636162RecruitingEarly Phase 1
Testing DSP-0390 before surgery for gliomas
This trial tests a drug called DSP-0390 in people with gliomas (a type of brain tumor). You take the drug for a short time before your scheduled surgery to see how it affects the tumor. It might help doctors find new ways to treat these tumors.
St Louis, MissouriAges 18 years+ - NCT06636201Recruiting
Cerebrospinal fluid study for surgery patients
This study collects and analyzes spinal fluid from patients having surgery with spinal anesthesia. It aims to learn more about the fluid's composition to help understand neurological conditions.
Hangzhou, ZhejiangAges birth–90 years - NCT06636318Recruiting
Immune changes during 24-hour surgery call
This study looks at how being on call for 24 hours affects the immune system of surgery residents. The goal is to see if these long shifts change how the body fights infection.
Chicago, IllinoisAges 18 years+ - NCT06636578RecruitingPhase 4
Adding dexmedetomidine to pain block for heart surgery
This study tests adding a medicine called dexmedetomidine to a standard pain-blocking injection (ropivacaine) used during heart surgery. The goal is to see if it reduces pain and speeds recovery better than the injection alone.
Al FayyumAges 20–65 - NCT06638385Recruiting
Space-expanding shield in stroke surgery
This trial tests a shield placed in the skull after removing a bone flap to treat swelling after a major stroke. The shield creates extra space for the brain to expand safely.
AarauAges 18–70 - NCT06638931RecruitingPhase 2
Nivolumab for rare solid tumors with high PD-L1
This trial is testing a drug called Nivolumab (an immunotherapy) for people with rare solid tumors that have high levels of PD-L1. It might be an option if you have tried other treatments and they stopped working or caused too many side effects.
Fortaleza, CearáAges 18 years+ - NCT06639009Recruiting
Laser treatment for better mouth opening in oral fibrosis
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
New Delhi, National Capital Territory of DelhiAges 18–99 - NCT06639022Recruiting
Pain relief after cervical spine surgery
This study compares two types of nerve blocks to see which provides better pain relief after neck surgery. It looks for patients scheduled for a specific neck procedure called anterior cervical discectomy.
Altındağ, AnkaraAges 18–80 - NCT06639282RecruitingPhase 2
Testing siponimod for mild Alzheimer's dementia
This study tests if a medicine called siponimod, already used for multiple sclerosis, can help people with mild Alzheimer's dementia. You will take a pill daily and be monitored closely for safety and cognitive changes.
Phoenix, ArizonaAges 50–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.