Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06719063Recruiting
Virtual reality therapy for left-side neglect after stroke
This study tests whether immersive virtual reality with added sensations (like sounds and touch) can help people who have trouble noticing their left side after a right-sided stroke. If you had a first right-sided stroke within the past 3 months and have left neglect, this might help you regain function.
Saint-Sébastien-de-MorsentAges 18 years+ - NCT06719245Recruiting
Preventing post-amputation pain with targeted nerve surgery
This trial tests a surgical procedure called targeted muscle reinnervation (TMR) to prevent pain after a leg amputation. The goal is to see if rerouting nerves during amputation can reduce phantom limb pain or stump pain.
Amsterdam, North HollandAges 18–75 - NCT06719583Recruiting
Black and African Americans Connections to Parkinson's Disease
This study is building a research registry to learn more about how Parkinson's disease affects Black and African American communities. If you have Parkinson's or are a healthy volunteer, you can join by giving a saliva sample for genetic research.
Birmingham, AlabamaAges 18 years+ - NCT06719791RecruitingEarly Phase 1
Sirolimus for hard-to-treat focal epilepsy
This trial tests if the drug sirolimus can help people with focal seizures (starting in one part of the brain) that don't improve with at least two other medications. It aims to reduce seizure frequency in adults aged 18 to 60.
BeijingAges 18–60 - NCT06720571Recruiting
Nerve stimulation for emotion and thinking in Prader-Willi syndrome
This trial tests whether a gentle, non-invasive nerve stimulation (like a small device on the neck) can help people with Prader-Willi syndrome regulate emotions and improve planning and focus. It may be a new option if you have trouble with emotional control or daily organization.
BordeauxAges 18 years+ - NCT06720545Recruiting
Short break from nerve stimulation therapy and heart health
This study looks at what happens to your heart health and metabolism when you stop using a nerve stimulator for sleep apnea for a short time. It may help understand the risks and benefits of taking a break from this therapy.
New York, New YorkAges 18 years+ - NCT06720922Recruiting
Laser surgery for drug-resistant epilepsy
This trial tests a new, less invasive surgery called MRI-guided laser ablation (MRgLITT) for people with drug-resistant mesial temporal lobe epilepsy. It aims to stop or reduce seizures by using a laser to destroy the tiny area of the brain causing them.
Beijing, Beijing MunicipalityAges Any age - NCT06721299RecruitingPhase 1
Testing clenbuterol for muscle health in FSHD
This study tests a medication called clenbuterol to see if it can reduce activity of the DUX4 gene, which is believed to cause muscle damage in FSHD. If you have FSHD type 1 or 2, you may be able to join and help researchers understand if this drug can improve muscle health.
Kansas City, KansasAges 18–75 - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06722170Recruiting
Gene therapy study for hearing loss caused by OTOF gene mutation
This trial tests a gene therapy called EH002 for people with severe or profound hearing loss due to changes in the OTOF gene. The treatment aims to help the ear hear better by replacing the faulty gene.
Zhengzhou, HenanAges 6 months+ - NCT06722222Recruiting
New surgery for carotid artery narrowing
This trial tests a specific surgical technique called Gao's Triple Eversion Carotid Endarterectomy for people with significant narrowing of the carotid artery. The goal is to prevent strokes by removing the blockage.
Hangzhou, ZhejiangAges Any age - NCT06722352Recruiting
Palliative care education for dementia in assisted living
This study trains staff in assisted living facilities to better support residents with dementia and their families in planning future care. It focuses on helping families talk about advance care planning (decisions about future medical care) with the care team.
Tampa, FloridaAges 21 years+ - NCT06722768Recruiting
Smart insole to detect walking changes from a spinal tap in NPH
This study checks if a special smart insole can detect changes in walking after a spinal tap test for people with suspected Normal Pressure Hydrocephalus (NPH). If you have walking problems and are considering a spinal tap, this trial might help find better ways to measure your response.
Yongin-si, Gyeonggi-doAges Any age - NCT06722755Recruiting
CPAP for Sleep Apnea After Stroke
This study tests whether using a CPAP machine (a device that helps you breathe while sleeping) can improve recovery after a recent stroke or brain bleed. You may join if you had a stroke in the past month and are not already using CPAP.
Downey, CaliforniaAges 18 years+ - NCT06723262Recruiting
Testing a new sound tuning for cochlear implant users
This trial studies a new way to adjust a cochlear implant's sound settings based on how the ear naturally processes pitches. It may help improve speech understanding over 6 months compared to standard settings.
LimogesAges 18 years+ - NCT06723353Recruiting
Combined therapy for belly separation in new mothers
This trial tests if a gentle hands-on treatment (visceral manipulation) plus special tape (kinesio taping) can help close the gap in your belly muscles, reduce pain, stop bladder leaks, and improve your pelvic floor strength and overall well-being after childbirth.
Karachi, SindhAges 35–45 - NCT06723444Recruiting
Improving Memory in Portuguese Patients with Multiple Sclerosis
This study tests a new method to improve memory and learning in people with multiple sclerosis who have mild memory problems. You'll undergo memory training and assessments to see if it helps.
PortoAges 18–70 - NCT06723717RecruitingPhase 2
Daily dornase alfa after aneurysm bleed for better recovery
This trial tests whether giving dornase alfa daily for up to 14 days after a subarachnoid hemorrhage (a type of bleeding around the brain from a burst aneurysm) helps people be more independent 6 months later. It is for people whose bleeding started less than 48 hours ago and whose aneurysm has already been treated.
Grenoble, GrenobleAges 18 years+ - NCT06723743Recruiting
Nerve stimulation for attention and memory
This study tests if a gentle, non-invasive nerve stimulation device can help improve attention and memory in veterans with PTSD, depression, or mild brain injury. It uses a small device on the ear to stimulate a nerve that may influence brain function.
Houston, TexasAges 25–64 - NCT06723951Recruiting
Quality of life questionnaire for spina bifida patients
This study tests a new questionnaire QUALAS to see how well it measures quality of life in Dutch people with and without spina bifida. If you have spina bifida or are a healthy volunteer, you may help validate this tool.
GroningenAges 8 years+ - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06725108Recruiting
Hemodynamic monitor for brain injury patients
This trial tests a new monitor that tracks blood flow in patients with severe traumatic brain injury or bleeding in the brain. The device may help doctors better manage care for these critically ill patients.
Chicago, IllinoisAges 18–80 - NCT06725784Recruiting
Robot-assisted arm rehab with different levels of supervision
This study tests a robot called ReHandyBot that helps people exercise their arm and hand. Researchers want to see if it works well when a therapist is nearby or far away, and how much it costs.
BrissagoAges 18–90 - NCT06725836Recruiting
Spinal cord stimulation study for spinal cord injury
This study tests how spinal cord stimulation affects brain activity in people with spinal cord injuries. It aims to understand the physiological effects using EEG (a brainwave test).
Vladivostok, Primorskiy (Maritime) KrayAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.