Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT03026816Recruiting
Epidural stimulation to improve function after spinal cord injury
This study tests whether stimulating the nerves in your spine (via an epidural device) can improve rehab-related function after a spinal cord injury. It focuses on people with stable, motor-complete paraplegia and long-term injuries, and it compares how you respond to the stimulation during rehabilitation.
Minneapolis, MinnesotaAges 22 years+ - NCT03304314Recruiting
Eye test study for pseudotumor cerebri and healthy volunteers
This study uses detailed eye measurements to compare findings in people with pseudotumor cerebri and in healthy eyes. It may help researchers understand how pupil responses and eye structure change with pseudotumor cerebri.
Tel LitwinskyAges 18–80 - NCT03065231Recruiting
Lumbar vs external brain fluid drain to prevent blood vessel spasm
This study compares two types of drainage tubes used in people with a serious bleeding around the brain, aiming to prevent a complication called blood vessel spasm. If you qualify, it may help doctors learn which drainage method works best for safer recovery.
San Diego, CaliforniaAges 18–110 - NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT02935283Recruiting
MRI brain and thinking tests in urea cycle disorders
This study uses MRI scans and memory/thinking tests to understand brain effects of urea cycle disorders, like ornithine transcarbamylase deficiency (OTCD) and argininosuccinate (ASSD/ASLD). It may help researchers understand how brain function changes during and between metabolic crises.
Washington D.C., District of ColumbiaAges 7–50 - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT03364803Recruiting
Sharing treatment results for people with Cushing’s syndrome
This is a study that collects and reviews information about how people with Cushing’s syndrome (including some mild forms and certain “silent” tumors) are diagnosed and treated, and what outcomes they have. It may help researchers understand which treatments work best in different types of the condition.
Basking Ridge, New JerseyAges 14 years+ - NCT03142022Recruiting
Sleep breathing study after lung transplant
This study checks sleep-related breathing problems (like pauses in breathing during sleep) in people about a year after a lung transplant. It uses a sleep test to understand what’s happening and may help guide better follow-up care.
LeuvenAges 18 years+ - NCT03336008Recruiting
Registry for certain inherited spinocerebellar ataxias
This study is a registry that collects information from adults with certain types of inherited ataxia caused by specific genetic diagnoses. It may help doctors better understand these conditions and support future research.
Hong Kong, ShatinAges 18–90 - NCT03334292Recruiting
Study of the natural course of Wilson disease
This study follows people who already have Wilson disease to understand how the condition changes over time. It may help researchers better predict future symptoms and improve care.
New Haven, ConnecticutAges Any age - NCT03149705Recruiting
Study group of adults with ischemic stroke
This study looks at adults who have had an ischemic stroke confirmed on MRI and a blockage in a major brain artery. Researchers want to understand stroke care in people who can receive standard clot-busting treatment (thrombolysis) and/or clot removal (thrombectomy).
BronAges 18 years+ - NCT03243175RecruitingPhase 3
Avoiding blood thinners after brain bleeding in atrial fibrillation
This Phase 3 trial studies whether it’s safer to avoid long-term blood thinners after a spontaneous brain bleed in people with atrial fibrillation (an irregular heart rhythm). It compares different prevention strategies to lower the risk of stroke or other blood-vessel problems without causing new, serious bleeding.
LilleAges 18 years+ - NCT03143374RecruitingPhase 2/Phase 3
Brain scan study for tau in neurodegenerative diseases
This study uses a special PET/CT brain scan to look at a protein called tau in people with memory/thinking and movement disorders. The results may help researchers understand how these diseases affect the brain and improve future diagnosis or care.
Philadelphia, PennsylvaniaAges 18–100 - NCT02945345Recruiting
Test how skin scores change in cutaneous dermatomyositis
This study looks at how well skin symptoms improve in adults with cutaneous dermatomyositis by using a specific skin-scoring tool. The results may help doctors better measure treatment response and guide care.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03217396Recruiting
Study blood and MRI markers in people with multiple sclerosis
This study looks for signs of “synapse damage” in multiple sclerosis using blood tests and brain imaging (MRI). The goal is to find biomarkers that may help better understand MS and how it changes over time.
Pozzilli, IserniaAges 18–65 - NCT03291392Recruiting
CUHK stroke biobank for blood, fluid, and tissue samples
This study builds a research bank using samples from people with stroke, their family members, and some people without narrowing in their blood vessels. Your samples help researchers study stroke and related brain and vessel changes.
Hong KongAges 18 years+ - NCT03325946Recruiting
Neuromotor research clinic for people with movement problems
This study is looking at people who have difficulties with movement or muscle control (neuromotor impairment). It may help researchers better understand these problems and improve future care.
Roanoke, VirginiaAges 3 months–18 years - NCT02929732Recruiting
Study muscle nerve activity in restless legs
This study looks at how active the nerves are in people with Willis-Ekbom disease (restless legs syndrome) and compares them with people without it. It may help researchers understand what drives symptoms and how the condition works in the body.
MontpellierAges 18–74 - NCT02945501Recruiting
Brain stimulation during sleep to improve slow-wave brain timing
This study tests a non-painful brain stimulation during the first part of sleep to see how it affects slow, deep-sleep brain rhythms. It is mainly for healthy young adults who can follow a strict sleep schedule.
Bethesda, MarylandAges 18–39 - NCT03137472Recruiting
Brain stimulation to treat complex regional pain syndrome
This trial studies whether noninvasive brain stimulation (TMS) can reduce pain in people with complex regional pain syndrome (CRPS). It may help if your CRPS has lasted at least a few months and you can safely undergo the stimulation and study tasks.
Redwood City, CaliforniaAges 18–70 - NCT03320759Recruiting
Improving recovery after non-traumatic spinal cord injury
This study looks at ways to help people recover after spinal cord injury that was not caused by trauma. It may help by testing an approach that is guided by regular MRI scans and repeat therapy visits.
London, OntarioAges 18 years+ - NCT03171012Recruiting
Exercise rehab with added movement retraining after stroke
This trial tests whether adding a specific movement-retraining method (proprioceptive neuromuscular facilitation) to heart-and-lung style exercise improves recovery after stroke. It focuses on people who still have one-sided weakness and can already walk a short distance.
Recife, PernambucoAges 21–65 - NCT03056794Recruiting
Study of genetic and natural history of PDC deficiency
This study looks at how pyruvate dehydrogenase complex (PDC) deficiency affects people over time and what genes are involved. It mainly helps by building genetic and health data, which may improve future care and understanding of the condition.
Pittsburgh, PennsylvaniaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.