Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,874 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,178
- Phase 1584
- Phase 3466
- Phase 1/Phase 2389
- Phase 4235
- Phase 2/Phase 3113
Top conditions
- Colorectal Cancer495
- Gastric Cancer297
- Pancreatic Cancer294
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer174
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer113
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)103
- Liver Cancer99
- Lung Cancer98
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University89
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California465
- Arizona175
- Texas146
- Florida134
- Massachusetts128
- New York123
- Alabama121
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,874 total
- NCT07708545RecruitingPhase 2
Comparing two drugs for bleeding ulcers
This trial tests whether a newer drug, tegoprazan, works as well as the standard drug lansoprazole for healing bleeding ulcers in the stomach or small intestine. You will get one of these drugs for 14 days and have a follow-up endoscopy to check healing.
Tangerang, BantenAges 18 years+ - NCT07298421RecruitingPhase 3
Testing afimkibart for children with Crohn's disease
This trial tests a medicine called afimkibart for children with moderately to severely active Crohn's disease. It aims to see how well the drug works and how safe it is when used for both starting and ongoing treatment.
New York, New YorkAges 2–17 - NCT07406633RecruitingPhase 2
KQB198 plus imatinib for advanced GIST
This trial tests a new drug called KQB198 combined with imatinib for people with advanced or metastatic gastrointestinal stromal tumor (GIST) that has a specific KIT or PDGFRA mutation. The goal is to see if this combination works better than imatinib alone as a first treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07686679RecruitingPhase 4
A study of DA-9701 for functional dyspepsia
This trial tests a drug called DA-9701 to see if it can help people with functional dyspepsia, a condition where you have stomach pain or discomfort without a clear physical cause. It aims to improve your digestive symptoms.
SeoulAges 19–75 - NCT05042544Recruiting
Testing program for people at risk of hepatitis C
This trial studies point-of-care (on-site) testing to find hepatitis C in adults who are at higher risk. If hepatitis C is found, earlier detection can help you get connected to care sooner.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT07416552RecruitingPhase 1
Study of CEA-PRIT 2.0 for advanced colorectal cancer
This trial tests an experimental drug called CEA-PRIT 2.0 in people whose colorectal cancer has spread and is no longer responding to standard treatments. The goal is to see if it can help shrink tumors or slow the cancer's growth.
Omaha, NebraskaAges 18 years+ - NCT00001184Recruiting
Studying the immune system in Crohn's and colitis
This study collects blood and tissue samples to better understand how the immune system behaves in people with inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis. It aims to advance research rather than test a specific new treatment, and it also enrolls healthy volunteers for comparison.
Bethesda, MarylandAges 1 day–75 years - NCT03481829Recruiting
Long-term study tracking health factors from pregnancy
This study follows pregnant mothers and their babies for years to understand how early life factors can affect health later. If you qualify, you and your child(ren) will be asked to stay in the research study for at least 3 years after delivery.
Phoenix, ArizonaAges 1 day–99 years - NCT05731141Recruiting
Study of lymphatic birthmarks and related genetic conditions
This study follows people who have lymphatic anomalies (lymphatic birthmarks) and sometimes related vascular or genetic conditions. It aims to better understand how these problems develop and what genetic causes may be involved.
Bethesda, MarylandAges 1 day–100 years - NCT06817031Enrolling by invitationPhase 2
Probiotics for gut health in pregnancy – Bangladesh study
This study tests whether a daily probiotic capsule during pregnancy can improve the health of a mother's gut, especially if she is exposed to unclean water or poor sanitation. Pregnant women early in their second trimester who live in the Matlab area of Bangladesh may join.
ChāndpurAges 18 years+ - NCT06808945Recruiting
Prehabilitation program for liver transplant patients
This study tests a pre-surgery exercise and nutrition program (prehabilitation) for people waiting for a liver transplant. It aims to see if getting stronger before surgery can help you recover better after the transplant.
RotterdamAges 18 years+ - NCT06784336RecruitingPhase 2
Testing starch and a drug after stem cell transplant
This trial tests if adding a special starch and a drug called deferasirox can improve recovery for people who have a stem cell transplant for blood disorders. The starch may help with gut health and the drug reduces iron, which might help prevent complications.
Ann Arbor, MichiganAges 18 years+ - NCT06781502Recruiting
Liver Disease and Transplant Study
This study is creating a database of people with severe liver problems or who have had a liver transplant. The goal is to learn more about these conditions and improve care.
Bologna, BolognaAges 18 years+ - NCT06778174Recruiting
Treating progressive familial intrahepatic cholestasis
This study tracks treatments and outcomes for people with a confirmed genetic form of PFIC, a rare liver disease. It helps doctors learn which treatments work best for each type.
GroningenAges Any age - NCT06767449Recruiting
Zolbetuximab for Claudin18.2 positive stomach cancer
This trial is for people with advanced stomach cancer that has a specific protein called Claudin18.2 and is HER2-negative. It tests whether continuing zolbetuximab—a drug that targets this protein—can help control the cancer.
SeoulAges 19 years+ - NCT06761287Recruiting
Choosing surgery after chemo for advanced rectal cancer
This study looks at patients with advanced rectal cancer who had treatment (chemotherapy or radiation) before surgery. They want to see if it's safe to avoid surgery in those who had a good response to initial treatment.
BrusselsAges 18 years+ - NCT06652906RecruitingPhase 2
A bowel prep study for people aged 50 to 70
This study tests a sodium phosphate powder for cleaning the bowel before a colonoscopy. It looks at how safe and effective it is for people in this age group.
Shanghai, Shanghai MunicipalityAges 50–70 - NCT06648083Recruiting
How very premature babies learn to eat by mouth
This study looks at how very premature babies (born at 28 weeks or earlier) learn to eat by mouth and whether they develop any feeding or mouth problems later. Researchers will review medical records from past years to see what helped or hindered their progress.
LyonAges Up to 6 months - NCT06543615Enrolling by invitation
Ultrasound stomach check before surgery in sleeve gastrectomy patients
This study uses ultrasound to measure how much stomach content remains after fasting in people who have had sleeve gastrectomy surgery. It aims to understand if the standard 8-hour fasting period is enough for this group before other surgeries.
Cairo, Cairo GovernorateAges 21–45 - NCT06530420Recruiting
New classification for first-time umbilical hernia repair
This study looks at a new way to classify first-time umbilical hernias to help doctors choose the best surgical approach. It may help improve recovery and results for people having their first hernia repair.
KrakowAges Any age - NCT06474234RecruitingPhase 2
Probiotic for Gut Health in Young Children
This study tests whether a probiotic (a 'good bacteria' supplement) can help balance the gut bacteria in young children. Your child may be able to join if they are healthy, under 7, and haven't taken probiotics or antibiotics recently.
Cheras, Kuala LumpurAges 1 month–7 years - NCT06467929Recruiting
Collecting images from endoscopy procedures in adults
This study collects videos and images from endoscopy procedures to help doctors better understand what they see. It is open to most adults undergoing a routine endoscopy, regardless of gender, race, or whether they are pregnant.
Ghent, East FlandersAges 18 years+ - NCT06452303Recruiting
Bariatric surgery patient registry study
This study follows people who have weight-loss surgery (bariatric surgery) to see how it affects their health. It may be an option if you have obesity or type 2 diabetes and meet certain weight and health criteria.
Beijing, Beijing MunicipalityAges 16–65 - NCT06342557Recruiting
App-Based Health Diary for Young Liver Transplant Patients
This study uses an app (ePRO Diary) to track your health after a liver transplant or while waiting for one. It’s designed for young people between 14 and 20 years old who are moving from pediatric to adult care.
Bergamo, MILANOAges 14–20
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,874 recruiting gastroenterology studies from the U.S. registry right now, out of 12,294 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.