Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT04210089Recruiting
Soft cast bandage for diabetic foot ulcers
This study tests whether a “total contact” soft cast bandage helps people heal diabetic foot ulcers. You may be asked to get your leg wrapped and have regular follow-up visits so the ulcer can be checked closely.
Minneapolis, MinnesotaAges 18 years+ - NCT04212494Recruiting
Aspirating clot during heart procedure for certain heart attacks
This trial studies whether removing (“aspirating”) a blood clot during an emergency heart procedure works better for people having a specific type of heart attack with a large clot burden. It may help improve blood flow after treatment, but it is only for patients who meet several timing and safety conditions.
Fuzhou, FujianAges 18 years+ - NCT04211259RecruitingEarly Phase 1
Loratadine to reduce bone pain during stem cell collection
This early trial studies whether loratadine (an allergy medicine) can reduce bone pain caused by G-CSF, which is used to help your body collect stem cells. If you have multiple myeloma and are preparing for stem cell mobilization, this may make treatment-related bone pain more tolerable.
New Brunswick, New JerseyAges 18 years+ - NCT04212455Recruiting
Study of blood tests linked to high blood pressure
This study looks at whether certain blood markers can help explain or predict high blood pressure in adults. It may help researchers understand hypertension better, which could support future prevention or treatment.
Guangzhou, GuangdongAges 18 years+ - NCT04215679Recruiting
Virtual reality plus mental practice for stroke hand recovery
This trial tests whether “motor imagery” done with virtual reality can improve hand function after a stroke. You may benefit if you have readable Turkish and enough thinking ability to follow the program.
Bolu, MerkezAges 18–80 - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT04218344Recruiting
Heart attack and chest pain study at Harefield hospital
This study follows people who come to Harefield for urgent heart-related chest pain and planned heart-vessel imaging (coronary angiography). It aims to better understand these conditions and what doctors see during the procedure, which may improve care for future patients.
Harefield, MiddlesexAges Any age - NCT04219670Recruiting
Using sensors to study stroke recovery in hospital and community
This study uses sensor recordings to learn how stroke recovery happens over time, including for people in the hospital and those living in the community. Your results may help improve future monitoring and rehabilitation after stroke.
Chicago, IllinoisAges 18 years+ - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT04225975Recruiting
Study brain activity in babies right after birth
This study measures a newborn’s brain activity immediately after delivery. It may help doctors better understand early brain function in healthy full-term babies.
AmiensAges 1 minute–15 minutes - NCT04227002Recruiting
Study for people with aortic valve problems
This trial is for people with aortic valve disease (aortic valve narrowing, leakage, or a worn-out valve). It tests what the doctors learn from following these patients, and it may help improve future care.
HamburgAges 18 years+ - NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT04229056Recruiting
Computer training to improve thinking and planning after stroke or Parkinson’s
This trial tests computer-based “self-training” to improve executive function, such as working memory—your ability to hold and use information in mind. It’s for adults with a prior stroke, cardiac arrest, or Parkinson’s disease who have trouble on a specific working-memory task.
CopenhagenAges 18–100 - NCT04230785Recruiting
Blood RNA test during clot-busting treatment for stroke
This trial studies special molecules in the blood (non-coding RNA) in people having an acute ischemic stroke treated with a procedure to remove clots. It may help doctors better understand how the body responds and potentially improve future stroke care.
Nanjing, JiangsuAges 18–90 - NCT04232631Recruiting
Noninvasive tests to help wounds heal in diabetes
This study uses noninvasive (no major procedures) tests to better understand how diabetic foot ulcers or infections are healing. It may help doctors choose better ways to support wound healing in people with diabetes.
Dallas, TexasAges 18–89 - NCT04234022Recruiting
Test a drug approach for multiple myeloma and leukemia
This trial studies a treatment aimed at a specific disease pathway in people with multiple myeloma or acute leukemia. It may help shrink or control cancer cells by targeting how they respond to low-oxygen conditions.
WolverhamptonAges 18 years+ - NCT04237701Recruiting
Tracking heart failure in real time at Yale
This trial looks at how people with heart failure are doing using real-time monitoring across the Yale New Haven Health System. It may help improve care by spotting problems sooner and tracking treatment effects.
New Haven, ConnecticutAges 18 years+ - NCT04240054RecruitingPhase 2
Study drugs before transplant for myeloma with kidney problems
This Phase 2 trial tests whether a combination of anti-myeloma medicines given before stem cell transplant works well and is safe for people with multiple myeloma who also have kidney problems. It may help control the myeloma and prepare you for the transplant.
Milwaukee, WisconsinAges 18 years+ - NCT04241328Recruiting
Cardiac surgery registry for patients who used a Medtronic device
This study tracks patients who had cardiac surgery using a specific Medtronic heart-surgery device. It mainly collects real-world data to help understand outcomes, and you may be included if you give consent and are not in another device/drug study that could affect the results.
ViennaAges Any age - NCT04240652Recruiting
Diabetes eye screening and prevention program for eye disease
This program aims to screen people for diabetic eye problems early and help prevent vision loss over time. It may help you if you have type 2 diabetes (or you’ve been invited as a diabetes/non-diabetes participant) and can safely take part in the study activities.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04240834RecruitingPhase 4
Low-dose ticagrelor vs aspirin after heart stent placement
This study compares ticagrelor taken at a lower dose versus regular aspirin to help prevent future heart attacks in people who recently had a stent placed after acute coronary syndrome. You may qualify if you’re considered “high risk” for new blockages or clots and can take dual anti-platelet therapy for 12 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04246463Recruiting
Aortic stent graft patient registry to track outcomes
This study is a registry that follows people who receive an aortic endovascular (through-the-blood-vessel) stent graft. It helps doctors understand how well these grafts work and what outcomes happen over time.
Long Beach, CaliforniaAges 18 years+ - NCT04247685Recruiting
MRI-safe heart rhythm test in people with atrial fibrillation
This trial checks whether a specific MRI-safe 12-lead heart recording (ECG) works correctly during MRI scans. It may help improve how doctors monitor heart rhythm while imaging, especially for people with atrial fibrillation.
Toronto, OntarioAges 18–90 - NCT04248205RecruitingPhase 4
Ketamine to reduce pain after hemorrhoid surgery
This trial tests whether ketamine can lessen pain after hemorrhoidectomy (surgery for severe hemorrhoids). It may help reduce how much pain medicine you need during recovery.
Oklahoma City, OklahomaAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.