Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07484009Recruiting
ReDS-guided fluid removal for heart failure patients
This trial tests if using a wearable monitor (ReDS) to guide fluid removal helps people hospitalized for heart failure. The goal is to find the right amount of fluid to remove so patients feel better and stay out of the hospital.
Madrid, MadridAges 18 years+ - NCT07489547RecruitingPhase 2/Phase 3
Can stable heart failure patients stop some medications?
This trial is testing whether people whose heart failure has improved (with better pumping strength) can safely stop taking some of their heart medications. It is for stable patients who have had significant improvement in their heart function from a low point.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07482501Recruiting
Magnetic brain stimulation for heart health after stroke
This study uses repetitive transcranial magnetic stimulation (a non-invasive brain treatment using magnetic pulses) to improve heart rate control in people who have had a stroke. It may help your body better manage stress and blood pressure.
AfyonkarahisarAges 35–80 - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT07486271Recruiting
AI in Aortic Regurgitation trial
This trial uses artificial intelligence to help measure aortic regurgitation, a heart valve problem. It aims to improve how doctors assess and treat this condition.
Hong Kong, New TerritoriesAges 18 years+ - NCT07483203Recruiting
Lung blood vessel health in people getting heart valve procedures
This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.
Rochester, MinnesotaAges 18 years+ - NCT07488247RecruitingPhase 3
Light-Activated Gel for Diabetic Foot Ulcers
This trial tests a gel containing a light-activated drug (chlorin E6) for diabetic foot ulcers. The gel is applied to the ulcer and then activated with a special light to help the wound heal. It may be a good option if you have a foot ulcer that hasn't healed in 6 weeks or more.
Karachi, SindhAges 18 years+ - NCT07485088Recruiting
Video to reduce anxiety before heart stent procedure
This trial tests if watching a video before a planned heart stent procedure can lower anxiety. If you are scheduled for this procedure and speak English, you may be eligible.
SingaporeAges 21 years+ - NCT07487961Recruiting
Checking abdominal aorta size in women
This study measures the diameter of the abdominal aorta in women aged 50 and older using an ultrasound. It aims to understand normal sizes and identify any enlargements that may need monitoring.
MilanAges 50 years+ - NCT07485647RecruitingPhase 2
Finding the best dose of daratumumab for multiple myeloma patients after transplant
This trial tests different dosing schedules of daratumumab to find a more cost-effective option for patients with multiple myeloma who have already had a stem cell transplant and achieved at least a partial response. It aims to see if a lower dose can work just as well.
Nashville, TennesseeAges 18–70 - NCT07489352Enrolling by invitation
Heart failure medication adjustment study
This study tests a personalized approach to safely increase the dose of your heart failure medication (beta-blocker). It aims to improve your symptoms and overall heart function by tailoring the dose to your specific needs.
New York, New YorkAges 50 years+ - NCT07488052Recruiting
Home ECG test to check heart health
This trial tests whether a simple home electrocardiogram (ECG) can be used to check your heart function. It may help find people who have a weak heart pump without needing a full heart ultrasound right away.
TaipeiAges 20–90 - NCT07485738Recruiting
Blood flow during bypass surgery and graft recovery
This study looks at how blood flow readings during coronary artery bypass surgery relate to whether the new grafts stay open and how well patients recover. It aims to help improve long-term results for people needing bypass surgery.
New York, New YorkAges 18 years+ - NCT07484477Recruiting
Sitting less to improve heart and lung function after heart surgery
This study tests whether helping people sit less and move more after heart surgery can improve their breathing, heart function, and quality of life. If you're between 50 and 80 and have had heart surgery, this may help you recover better.
Peshawar, KPKAges 50–80 - NCT07489534RecruitingPhase 2
CAR-T therapy for multiple myeloma with kidney problems
This trial tests a new type of cell therapy (CAR-T cells) for people with multiple myeloma who also have kidney problems. It aims to see if this treatment can help keep the cancer in remission after initial therapy.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07486570Recruiting
Stenting to prevent leaks after colon surgery
This trial tests if placing a small mesh tube (stent) in a major artery can prevent leaks where the colon is reconnected during surgery. It may help people who have a blockage in that artery but no symptoms from it.
Emmen, DrentheAges 40 years+ - NCT07484854Recruiting
FES-assisted arm bike training for recent stroke recovery
This study tests whether adding Functional Electrical Stimulation (FES) to arm bike exercises can help improve arm movement in people who had a stroke within the last six months. It is designed for those with weakness on one side of the body.
Ankara, ÇankayaAges 18–85 - NCT07481396Recruiting
Studying brain injury after cardiac arrest through spinal fluid
This trial is looking at the spinal fluid of people who survived a cardiac arrest outside the hospital and are being treated for brain injury. The goal is to learn more about brain damage and find new ways to help patients recover.
Daejeon, Jung-guAges 18 years+ - NCT07482462Recruiting
Blood pressure and heart rate study in healthy and hypertensive adults
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
LjubljanaAges 18 years+ - NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06775457Recruiting
Genetic study of HERVs in children with new inflammation
This study looks at certain genes (called HERVs) in children with new inflammatory conditions like Kawasaki disease, COVID-19, or other infections. It aims to learn more about how these genes might be involved in the body's response to illness.
Carpi, ModenaAges Up to 18 years - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT06776458Recruiting
Aromatase inhibitor effects on heart and brain health in breast cancer
This study looks at how aromatase inhibitors (a type of hormone therapy for breast cancer) affect your heart and brain health over time. It compares women with breast cancer who have taken these drugs to healthy women of similar age.
Toronto, OntarioAges Any age - NCT06776133Recruiting
Predicting heart pressure from vein size in children
This study looks at a possible link between the size of a large vein (the inferior vena cava) and the pressure in the right side of the heart in children. If the link is strong, doctors might one day use vein size to estimate heart pressure without more invasive tests.
Bologna, BolognaAges Up to 18 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.