Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT06775821Recruiting
Lung cancer and abdominal aneurysm screening study
This study looks at how common abdominal aortic aneurysms (bulges in the belly's main artery) are in people with primary lung cancer. It involves a simple imaging test to check for this condition.
Kunming, YunnanAges 20–90 - NCT05786131Recruiting
Stent treatment: fix all blocked arteries vs culprit only
This trial compares two ways of doing a stent procedure in people who had an NSTEMI heart attack: fixing all significant blockages versus fixing only the “culprit” blockage. It may help find which approach is safer and more effective for preventing complications.
GrazAges 18 years+ - NCT05373498Recruiting
Registry for children’s heart emergencies after resuscitation
This trial is a registry that collects information about children (under 18) who have congenital heart problems and need resuscitation with chest compressions. It helps doctors understand these emergencies and may improve future care for similar patients.
Leipzig, SaxonyAges Up to 18 years - NCT06115135RecruitingPhase 2
Venetoclax with isatuximab and dexamethasone for myeloma
This trial tests a combination of three drugs (venetoclax, isatuximab, and dexamethasone) for people with multiple myeloma that has come back or stopped responding to earlier treatments. It is for patients whose cancer cells have a specific genetic change, called t(11;14).
West Hollywood, CaliforniaAges Any age - NCT06009718Recruiting
Heart sound and heartbeat analysis study
This study uses artificial intelligence to analyze your heart sounds and heartbeat together to see if this can help understand heart health better. It might lead to easier heart checkups in the future.
ShanghaiAges 18–100 - NCT06225310RecruitingPhase 1
New combo for relapsed/refractory multiple myeloma
This trial tests a three-drug combination (selinexor, ruxolitinib, and methylprednisolone) for people with multiple myeloma that has come back or stopped responding after at least three prior treatments. The goal is to see if this new combination can help control the cancer.
West Hollywood, CaliforniaAges Any age - NCT06611319RecruitingPhase 3
Shorter blood thinner after hip replacement: a recovery study
This study tests a shorter course of blood thinner medication (rivaroxaban) after hip replacement surgery, following an enhanced recovery plan. It aims to see if a shorter treatment can safely prevent blood clots and help you recover faster.
Linz, Upper AustriaAges 18–85 - NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT06779513Recruiting
New EKG score to detect heart stiffness in high blood pressure
This study tests a new scoring method using your heart's electrical signals (EKG) and imaging to detect early stiffness of the heart's main pumping chamber, which often goes unnoticed in people with high blood pressure. If you have high blood pressure and no other major heart or kidney problems, you may be able to join.
Semarang, Central of JavaAges 18–70 - NCT06779110Recruiting
OCT vs. X-ray guidance for treating re-blocked stents
This study compares the standard X-ray guidance (angiography) with a more detailed imaging test (OCT) to guide treatment for a re-blocked stent. It aims to see which method leads to better outcomes for patients with in-stent renarrowing.
Aosta, AostaAges 18–99 - NCT06552299Recruiting
Testing how well people measure CPR depth and length
This study compares how accurately laypeople and healthcare providers estimate the depth and length of CPR chest compressions. It helps researchers understand if training or experience affects measurement accuracy.
SeoulAges 18 years+ - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Atlantic City, New JerseyAges 18–80 - NCT06477042Recruiting
Act on quality of life in patients with aortic stenosis
This trial studies how a TAVI procedure affects the quality of life of people with aortic stenosis, especially those with multiple health conditions. It may help doctors understand how this treatment improves daily living for patients like you.
Clermont-FerrandAges 18 years+ - NCT07477912RecruitingPhase 1/Phase 2
BCMA-targeting CAR-T for relapsed/refractory multiple myeloma
This trial tests a new kind of immunotherapy called CAR-T that targets BCMA on myeloma cells. It is for people whose multiple myeloma has come back after or not responded to at least two previous treatments.
MinskAges 18 years+ - NCT07474935Recruiting
Real-world stroke treatment device registry
This trial collects information about the use of a specific stroke treatment device in real-world medical practice. It helps researchers see how well this device works for a wide range of patients, not just those in strict study conditions.
BrestAges Any age - NCT07479433Recruiting
New approach to plan stent placement using CT scans
This study tests if using a special CT scan analysis can help doctors plan where to place stents for blocked arteries. It might make the procedure safer and more effective for people who are scheduled for a planned stent procedure.
Marietta, GeorgiaAges 18 years+ - NCT07477587RecruitingPhase 1
Comparing two myeloma treatments for new patients
This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.
Springdale, ArkansasAges 18 years+ - NCT07473700RecruitingPhase 2
Study of TX000045 for lung scarring and high blood pressure in the lungs
This trial tests a new medicine called TX000045 for people who have both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug can help improve breathing and daily function.
Phoenix, ArizonaAges 18–80 - NCT07479992Recruiting
Using AI to detect aortic stenosis from ECG
This study tests a new AI tool that can spot aortic stenosis (a narrowed heart valve) by analyzing your ECG. It may help find the condition earlier, when treatment is more effective.
BonnAges 18 years+ - NCT06758271Recruiting
Long-term study of avacopan for vasculitis
This study looks at the long-term safety and effectiveness of avacopan in people with certain types of vasculitis (GPA or MPA). It may help doctors understand how well the medicine works over time.
Multiple LocationsAges Any age - NCT06780514Recruiting
Exercise testing for girls with Turner syndrome
This study will have girls with Turner syndrome do a cardiopulmonary exercise test (a special bike or treadmill test) to check how their heart and lungs work during exercise. It may help doctors better understand fitness and health in Turner syndrome.
GhentAges 8–18 - NCT07476040Recruiting
Better care for new stable chest pain
This trial tests a new way to manage stable chest pain that started recently. It aims to improve diagnosis and treatment for people suspected of having coronary artery disease.
AugsburgAges 30 years+ - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.