Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07472660Recruiting
Web-based prevention program after heart failure hospitalization
This trial tests a web-based prevention program for people recently hospitalized with heart failure (with low pumping ability). The goal is to help you stay healthier and avoid another hospital stay.
BremenAges 18–80 - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT07476859RecruitingPhase 4
Iron for heart attack recovery in older adults
This study tests whether giving iron through a vein can improve quality of life in older adults who recently had a heart attack or unstable angina and also have low iron levels. If you qualify, you would receive either iron or a placebo (inactive substance) to see if iron helps you feel better and recover faster.
El Palmar, MurciaAges 65 years+ - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07479147Recruiting
Stroke prevention in elderly by PFO closure vs blood thinners
This trial compares two treatments for preventing another stroke in older adults who have a PFO (a small hole in the heart). It tests whether closing the hole with a device works better than using blood-thinning medication.
TaichungAges 18–90 - NCT07475611Enrolling by invitation
Screen-based rehab for visual neglect after stroke
This study tests whether an interactive screen helps people with left-sided neglect after a stroke. It includes adults who had a right-sided stroke and have trouble paying attention to the left side of their world.
Buenos Aires, EscobarAges 18–88 - NCT07471919Recruiting
Robot vs. visual feedback balance training after stroke
This study compares two types of therapy—robot-assisted walking training and balance training using visual feedback—to see which helps improve walking and balance after a stroke. You may join if you had an ischemic or hemorrhagic stroke, can walk with some help, and have no major communication or vision problems.
BoluAges 21–85 - NCT07479979RecruitingPhase 1/Phase 2
Study of selinexor with carfilzomib, isatuximab and dexamethasone for relapsed/refractory multiple myeloma
This trial tests a combination of four drugs (selinexor, carfilzomib, isatuximab, and dexamethasone) in patients whose multiple myeloma has come back or stopped responding to prior treatment. The goal is to see if this combination can shrink the cancer and help patients whose disease has high-risk features, like certain chromosome changes.
Madison, WisconsinAges 18 years+ - NCT07476196Recruiting
Poland-Italy Aortic Aneurysm Stent Registry
This study is a registry that tracks how well stent grafts work for people with aortic aneurysms in Italy and Poland. It helps doctors understand which patients do best with this treatment.
Castel VolturnoAges 18 years+ - NCT07478003RecruitingPhase 3
Early steroid for severe heart attacks before reaching the hospital
This study tests whether giving a high dose of a steroid medication (glucocorticoid) early, before reaching the hospital, can help people having a severe type of heart attack called STEMI. If you are having this specific heart attack and meet the criteria, receiving this medication might improve your recovery.
AalborgAges 18 years+ - NCT07476040Recruiting
Better care for new stable chest pain
This trial tests a new way to manage stable chest pain that started recently. It aims to improve diagnosis and treatment for people suspected of having coronary artery disease.
AugsburgAges 30 years+ - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70 - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07478887Recruiting
Corrie Lipids app for better cholesterol management
This study tests a smartphone app called Corrie Lipids to help people with high cholesterol get their LDL levels under control. It may be a good fit if you have high cholesterol that isn't well managed and you have heart disease risk factors like diabetes or a family history.
Baltimore, MarylandAges 18 years+ - NCT07480265Recruiting
Homocysteine and early heart function in new high blood pressure
This study looks at a substance in your blood called homocysteine and how it affects the early filling of your heart's main pumping chamber. It may help doctors understand heart risks in people newly diagnosed with high blood pressure.
Konya, MeramAges 18 years+ - NCT07475949RecruitingPhase 3
Stroke treatment for unknown wake-up time
This trial tests a clot-busting drug for people who had a stroke but don't know when it started, like waking up with symptoms. It may help reduce disability if given soon after noticing symptoms.
Xiamen, FujianAges 18 years+ - NCT07478354Recruiting
Heart Tissue and Blood Study for Pediatric Heart Disease
This study collects samples (blood, tissue, and other specimens) from people of all ages who have or are at risk for pediatric heart disease. The goal is to build a research bank to better understand these conditions and develop new treatments.
Cincinnati, OhioAges Any age - NCT07475936Recruiting
Tenecteplase for very old patients with stroke
This trial tests if a clot-busting drug called tenecteplase is safe and effective for people over 80 who have an ischemic stroke and can get treatment within 4.5 hours of symptoms starting.
Nanning, GuangxiAges 80 years+ - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT07472049Recruiting
Imaging plaque activity in peripheral artery disease
This trial studies plaque activity in leg arteries using a new imaging method to understand artery disease better. It may help people with peripheral artery disease get more targeted treatment.
Edinburgh, MidlothianAges 18 years+ - NCT07479186Recruiting
How aortic disease affects quality of life and work
This study looks at how having an aortic disease (a problem with the main artery from your heart) impacts your daily life and ability to work. It aims to help doctors better understand and support patients like you.
Roma, RMAges 18–70 - NCT07476274Recruiting
Study of pneumonia after heart bypass surgery
This trial looks at pneumonia that happens in the hospital after coronary artery bypass surgery. It aims to understand who is at risk and how to better prevent or treat it.
Tomsk, Tomsk OblastAges 18 years+ - NCT07473102RecruitingEarly Phase 1
PET scan for abdominal aortic aneurysm
This study uses a special PET scan to look for signs of inflammation in abdominal aortic aneurysms (AAA). It may help doctors understand which aneurysms are at risk of growing or rupturing.
St Louis, MissouriAges 18 years+ - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.