Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,984 recruiting studies in this area right now.
By phase
- Not applicable7,964
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,981 total
- NCT04310098Recruiting
CADASIL registry for confirmed patients and mutation carriers
This study builds a group “registry” of people affected by CADASIL (a genetic brain blood-vessel condition) and people who carry the NOTCH3 mutation, even if they have no symptoms. It helps researchers learn more about the condition over time and compare experiences between patients, carriers, and healthy relatives or controls.
Fuzhou, FujianAges 18–85 - NCT04307992Recruiting
Preventing a common leak after AAA endovascular repair
This trial looks at adding a protective “fill” during surgery for an aneurysm in the lower part of the aorta, to prevent a specific type of leak called type II. It may help reduce the need for additional follow-up treatments if leaks are less likely to happen.
Amsterdam, North HollandAges 18 years+ - NCT04312269Recruiting
Brain stimulation plus memory practice to improve stroke arm recovery
This trial tests whether a combined therapy—MyoCI plus memory “reactivation”—can improve arm movement recovery after stroke. It’s meant for people with ongoing arm weakness at least 6 months after their first stroke.
Chicago, IllinoisAges 21–100 - NCT04312451Recruiting
Study of severe leg blood-flow problems after a procedure
This study follows adults with very poor blood flow to the foot or leg (with wounds or severe pain) who are having a revascularization procedure to improve circulation. It may help doctors understand outcomes after treatment and improve care for people with critical limb ischemia.
ParisAges 18 years+ - NCT04314752Recruiting
Study on multiple myeloma disparities in California patients
This study builds research tools to better understand and address differences in multiple myeloma outcomes for different groups. You may be able to help if you were diagnosed recently and live in California.
Sacramento, CaliforniaAges 21 years+ - NCT04318119Recruiting
Brain scan registry for small blood vessel disease
This study is a registry that collects information and brain scan findings from adults with possible small vessel disease. It may help doctors better understand how this condition looks on scans and what it is linked to.
Fuzhou, FujianAges 18–100 - NCT04319627RecruitingPhase 3
Statins to prevent new blood clots after leg clot or lung clot
This trial tests whether taking a statin (rosuvastatin) after a recent leg blood clot (DVT) and/or lung blood clot (PE) can lower the chance of future venous clots. You might benefit if you’re at risk for more clotting and can take the study medication safely.
Calgary, AlbertaAges 18 years+ - NCT04321512Recruiting
Blood test study for people with heart or stroke problems
This study looks at a type of white blood cell (monocytes) in blood to understand differences in people with certain heart attacks, stable heart disease, or ischemic stroke. It may help researchers learn why these conditions happen and how the immune system may be involved.
Farmington, ConnecticutAges 18 years+ - NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT04330287Recruiting
Study of heart health in adults aging with HIV
This study looks at how aging affects heart health in people who have HIV. It may help researchers find better ways to prevent or monitor heart problems over time.
Essen, NordrheinwestfalenAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT04330729Recruiting
Aspirin effect on blood clotting in kidney disease
This study checks how aspirin (also called salicylate) affects how platelets work, which helps blood clot. It involves people with advanced chronic kidney disease who are treated with Aranesp, and it may help guide safer care.
RoskildeAges 18–85 - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT04334031Recruiting
Hospital follow-up study for immune-related disease
This is a study that follows people with an immune-related illness at Lille University Hospital to better understand their care needs over time. By collecting information regularly, the study may help improve how future patients are monitored and treated.
LilleAges 18 years+ - NCT04336644Recruiting
Checks heart rhythm continuously or intermittently during treatment
This study compares two ways of monitoring your heart rhythm while you start certain cancer treatments. It may help doctors detect heart rhythm changes earlier and decide which monitoring approach is better.
St Louis, MissouriAges 18 years+ - NCT04339699Recruiting
PFO closure comparison trial for cryptogenic stroke
This trial studies ways to close a patent foramen ovale (PFO) to help prevent another stroke in people whose prior stroke had an unknown cause. If you qualify, you may receive one of the PFO closure approaches the study is comparing.
Tucson, ArizonaAges 18–60 - NCT04343313Recruiting
Transcatheter repair for leaky mitral valve in high-risk adults
This pilot study tests a newer catheter-based way to reduce leakage of the mitral valve in people who feel sick from mitral regurgitation but are considered too high-risk for standard surgery. If you fit the valve and heart anatomy needs, the study may help improve symptoms and valve function without open-heart surgery.
New York, New YorkAges 21–95 - NCT04344912Recruiting
Study of COVID-19 effects on heart emergency care
This study looks at how the COVID-19 outbreak affected care for people admitted to the cardiac intensive care unit. It may help hospitals improve how they plan and respond during major outbreaks.
ParisAges 18 years+ - NCT04347655Recruiting
Studies blood flow and heart pumping in adults with heart failure
This study looks at how well blood moves through the body and how strongly the left side of the heart pumps in adults. It compares people who have heart failure to people who do not, to better understand differences and possible causes.
Calgary, AlbertaAges 18 years+ - NCT04347200Recruiting
Long-term blood-thinner therapy registry for heart disease
This study follows people with known coronary artery disease to understand how long-term “blood thinner” treatments are used and how they affect health over time. You may be asked to share medical information and come in for follow-up to help researchers compare outcomes.
MoscowAges 18 years+ - NCT04345627Recruiting
Japanese registry for patients having lead removal from veins
This study collects information about people in Japan who need a procedure to remove heart device wires (leads) through a vein. It helps doctors understand outcomes and improve care for future patients.
Suita, OsakaAges Any age - NCT04347187Recruiting
Long-term blood-thinner study for atrial fibrillation patients
This trial follows people with atrial fibrillation to see how long-term blood-thinning treatment affects outcomes over time. It may help determine which long-term approach best lowers stroke and clot risks for patients like you.
MoscowAges 18 years+ - NCT04347434RecruitingPhase 4
Long-term cholesterol medicines after heart attack
This trial studies how well long-term cholesterol-lowering treatment works in people who recently had a heart attack (STEMI or NSTEMI). It may help your care team understand which patients benefit most and how treatment should be continued safely.
PenzaAges 30–70 - NCT04347785Recruiting
Study nerve effects after carotid surgery done with local anesthesia
This trial looks at what factors predict new or worsening nerve symptoms after a carotid endarterectomy (a surgery to clear plaque in the neck artery) when done with regional anesthesia. It may help doctors better anticipate and prevent neurologic problems during this procedure.
PortoAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,984 recruiting cardiology studies from the U.S. registry right now, out of 15,291 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.